TOP TEN perturbations for P91891 (Drosophila melanogaster)

Organism: Drosophila melanogaster
Gene: P91891
Selected probe(set): 1628281_at
Platform: Affymetrix Drosophila Genome 2.0 Array

Expression of P91891 (1628281_at) across 211 perturbations tested by GENEVESTIGATOR:

Lsm1 depletion study 1 (RNAi) / control RNAi transfected S2 cell sample

Relative Expression (log2-ratio):-1.358182
Number of Samples:2 / 2
Experimental Lsm1 depletion study 1 (RNAi)
Drosophila melanogaster S2 cells treated 9 days with Lsm1 specific RNAi.
Control control RNAi transfected S2 cell sample
Drosophila melanogaster S2 cells treated 9 days with GFP specific RNAi.

Nup153 depletion study 2 (RNAi) / control RNAi transfected S2 cell sample

Relative Expression (log2-ratio):-1.0060425
Number of Samples:3 / 3
Experimental Nup153 depletion study 2 (RNAi)
Drosophila melanogaster S2 cells treated 7 days with Nup153 (nuclear pore component 153) specific RNAi.
Control control RNAi transfected S2 cell sample
Drosophila melanogaster S2 cells treated 7 days with GFP specific RNAi.

S2 cell line / Kc167 cell line

Relative Expression (log2-ratio):-0.9885483
Number of Samples:6 / 6
Experimental S2 cell line
Schneider line 2 cells derived from a primary culture of late stage (20-24 hours old) Drosophila melanogaster Oregon-R embryos by Schneider in 1972. The S2 cell line is commonly used for heterologous protein expression in the Drosophila Expression System
Control Kc167 cell line
Cell line derived from a dorsal closure stage (6-12 hours old) Drosophila melanogaster embryo. Clone 167 isolated in Goldschmitt-Clermont laboratory, selected for growth in high-pH medium by Bourouis and Jarry and restored to normal medium in Cherbas laboratory.

Pat1 depletion study 1 (RNAi) / control RNAi transfected S2 cell sample

Relative Expression (log2-ratio):-0.97634697
Number of Samples:2 / 2
Experimental Pat1 depletion study 1 (RNAi)
Drosophila melanogaster S2 cells treated 9 days with Pat1 specific RNAi.
Control control RNAi transfected S2 cell sample
Drosophila melanogaster S2 cells treated 9 days with GFP specific RNAi.

dietary study 1 (low) / dietary study 1 (high)

Relative Expression (log2-ratio):-0.755702
Number of Samples:3 / 3
Experimental dietary study 1 (low)
Adult male Drosophila melanogaster w[1118] flies cultured in 0.25% YE (yeast extract) and sucrose as a constant carbon source for 6 days. RNA samples were taken from the whole fly as follows: RNA was separated using a sucrose gradient and prepared from low (1 to 4 ribosmes bound) translation fractions.
Control dietary study 1 (high)
Adult male Drosophila melanogaster w[1118] flies cultured in 0.25% YE (yeast extract) and sucrose as a constant carbon source for 6 days. RNA samples were taken from the whole fly as follows: RNA was separated using a sucrose gradient and prepared from high (5 or more ribosmes bound) translation fractions.

wt x UAS-Inr / wt x UAS-Inr

Relative Expression (log2-ratio):-0.6149063
Number of Samples:3 / 3
Experimental wt x UAS-Inr
Drosophila melanogaster UAS-Inr Insulin-like receptor responder line in a not specified wild type genetic background. Expression of UAS-Inr is induced by the hs-Flp; tub>CD2>UAS-Gal4, UAS-GFP system.
Control wt x UAS-Inr
Drosophila melanogaster UAS-Inr Insulin-like receptor responder line in a not specified wild type genetic background.

starvation study 2 (precise excision) / normal feed

Relative Expression (log2-ratio):-0.53162
Number of Samples:3 / 3
Experimental starvation study 2 (precise excision)
Mid-L3 stage larvae of transheterozygous Drosophila melanogaster "precision excision" line starved for 24 hours before taking samples of the whole larvae.
Control normal feed
Mid-L3 stage larvae of transheterozygous Drosophila melanogaster "precision excision" line fed with normal food for 24 hours before taking samples of the whole larvae.

delg613/Df(3R)ro80b / +/Df(3R)ro80b

Relative Expression (log2-ratio):-0.52189636
Number of Samples:3 / 3
Experimental delg613/Df(3R)ro80b
Control +/Df(3R)ro80b

yw; egg235/CyO / yw; +/CyO

Relative Expression (log2-ratio):0.49690056
Number of Samples:3 / 4
Experimental yw; egg235/CyO
Control yw; +/CyO

Dsec / sim6

Relative Expression (log2-ratio):0.44920158
Number of Samples:2 / 2
Experimental Dsec
Drosophila sechellia
Control sim6
Drosophila simulans isofemale line from Winters, Ca.