TOP TEN perturbations for 1002_f_at (Homo sapiens)

Organism: Homo sapiens
Gene: 1002_f_at
Selected probe(set): 216058_s_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 1002_f_at (216058_s_at) across 6672 perturbations tested by GENEVESTIGATOR:

hepatoblastoma study 1 (embryonal) / normal liver tissue

Relative Expression (log2-ratio):-5.9050503
Number of Samples:7 / 5
Experimental hepatoblastoma study 1 (embryonal)
Liver tumor tissue samples from children with hepatoblastoma (epithelial type (E-HB); embryonal subtype). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group.
Control normal liver tissue
Normal liver tissue samples.

hepatoblastoma study 1 (NOS) / normal liver tissue

Relative Expression (log2-ratio):-5.862378
Number of Samples:5 / 5
Experimental hepatoblastoma study 1 (NOS)
Liver tumor tissue samples from children with hepatoblastoma (NOS). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group.
Control normal liver tissue
Normal liver tissue samples.

hepatoblastoma study 1 (mixed epithelial and mesenchymal) / normal liver tissue

Relative Expression (log2-ratio):-5.6530275
Number of Samples:4 / 5
Experimental hepatoblastoma study 1 (mixed epithelial and mesenchymal)
Liver tumor tissue samples from children with hepatoblastoma (mesenchymal type (MEM-HB); mixed epithelial and mesenchymal subtype). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group.
Control normal liver tissue
Normal liver tissue samples.

hepatoblastoma study 1 (epithelial mixed) / normal liver tissue

Relative Expression (log2-ratio):-5.6484013
Number of Samples:12 / 5
Experimental hepatoblastoma study 1 (epithelial mixed)
Liver tumor tissue samples from children with hepatoblastoma (epithelial type (E-HB); epithelial mixed subtype). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group.
Control normal liver tissue
Normal liver tissue samples.

Hep-G2 / HepaRG

Relative Expression (log2-ratio):-5.5245485
Number of Samples:9 / 12
Experimental Hep-G2
Human primary cancer cell line derived from the liver of a patient with hepatocellular carcinoma. Synonyms:HEP-G2; Hep G2; HEP G2; HepG2; HEPG2 Cellosaurus code:
Control HepaRG
Immortalized cancer cell line derived from female patient with hepatocellular carcinoma. Cells can be induced to differentiate into hepatocyte-like cells by exposure to DMSO. Synonyms:Hepa-RG Cellosaurus code:

hepatocyte (ESC) / HepaRG

Relative Expression (log2-ratio):-5.482259
Number of Samples:8 / 12
Experimental hepatocyte (ESC)
Hepatocyte-like cells differentiated from embryonic stem cells (ESC)
Control HepaRG
Immortalized cancer cell line derived from female patient with hepatocellular carcinoma. Cells can be induced to differentiate into hepatocyte-like cells by exposure to DMSO. Synonyms:Hepa-RG Cellosaurus code:

HCC study 9 (HBV; HCV) / normal liver tissue

Relative Expression (log2-ratio):-4.9555063
Number of Samples:2 / 10
Experimental HCC study 9 (HBV; HCV)
Liver tissue biopsy sample from patients with Hepatitis B and C infection related hepatocellular carcinoma (HCC) after resection.
Control normal liver tissue
Normal, non-tumor liver tissue.

HCC study 9 (HCV) / normal liver tissue

Relative Expression (log2-ratio):-4.682233
Number of Samples:9 / 10
Experimental HCC study 9 (HCV)
Liver tissue biopsy sample from patients with Hepatitis C infection related hepatocellular carcinoma (HCC) after resection.
Control normal liver tissue
Normal, non-tumor liver tissue.

HCC study 9 (alcohol) / normal liver tissue

Relative Expression (log2-ratio):-4.6799307
Number of Samples:24 / 10
Experimental HCC study 9 (alcohol)
Liver tissue biopsy sample from patients with alcohol abuse related hepatocellular carcinoma (HCC) after resection.
Control normal liver tissue
Normal, non-tumor liver tissue.

HCC study 9 (HBV) / normal liver tissue

Relative Expression (log2-ratio):-4.578867
Number of Samples:10 / 10
Experimental HCC study 9 (HBV)
Liver tissue biopsy sample from patients with Hepatitis B infection related hepatocellular carcinoma (HCC) after resection.
Control normal liver tissue
Normal, non-tumor liver tissue.

Organism: Homo sapiens
Gene: 1002_f_at
Selected probe(set): 216058_s_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 1002_f_at (216058_s_at) across 6672 perturbations tested by GENEVESTIGATOR:

hepatoblastoma study 1 (embryonal) / normal liver tissue

Relative Expression (log2-ratio):-5.9050503
Number of Samples:7 / 5
Experimental hepatoblastoma study 1 (embryonal)
Liver tumor tissue samples from children with hepatoblastoma (epithelial type (E-HB); embryonal subtype). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group.
Control normal liver tissue
Normal liver tissue samples.

hepatoblastoma study 1 (NOS) / normal liver tissue

Relative Expression (log2-ratio):-5.862378
Number of Samples:5 / 5
Experimental hepatoblastoma study 1 (NOS)
Liver tumor tissue samples from children with hepatoblastoma (NOS). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group.
Control normal liver tissue
Normal liver tissue samples.

hepatoblastoma study 1 (mixed epithelial and mesenchymal) / normal liver tissue

Relative Expression (log2-ratio):-5.6530275
Number of Samples:4 / 5
Experimental hepatoblastoma study 1 (mixed epithelial and mesenchymal)
Liver tumor tissue samples from children with hepatoblastoma (mesenchymal type (MEM-HB); mixed epithelial and mesenchymal subtype). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group.
Control normal liver tissue
Normal liver tissue samples.

hepatoblastoma study 1 (epithelial mixed) / normal liver tissue

Relative Expression (log2-ratio):-5.6484013
Number of Samples:12 / 5
Experimental hepatoblastoma study 1 (epithelial mixed)
Liver tumor tissue samples from children with hepatoblastoma (epithelial type (E-HB); epithelial mixed subtype). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group.
Control normal liver tissue
Normal liver tissue samples.

Hep-G2 / HepaRG

Relative Expression (log2-ratio):-5.5245485
Number of Samples:9 / 12
Experimental Hep-G2
Human primary cancer cell line derived from the liver of a patient with hepatocellular carcinoma. Synonyms:HEP-G2; Hep G2; HEP G2; HepG2; HEPG2 Cellosaurus code:
Control HepaRG
Immortalized cancer cell line derived from female patient with hepatocellular carcinoma. Cells can be induced to differentiate into hepatocyte-like cells by exposure to DMSO. Synonyms:Hepa-RG Cellosaurus code:

hepatocyte (ESC) / HepaRG

Relative Expression (log2-ratio):-5.482259
Number of Samples:8 / 12
Experimental hepatocyte (ESC)
Hepatocyte-like cells differentiated from embryonic stem cells (ESC)
Control HepaRG
Immortalized cancer cell line derived from female patient with hepatocellular carcinoma. Cells can be induced to differentiate into hepatocyte-like cells by exposure to DMSO. Synonyms:Hepa-RG Cellosaurus code:

HCC study 9 (HBV; HCV) / normal liver tissue

Relative Expression (log2-ratio):-4.9555063
Number of Samples:2 / 10
Experimental HCC study 9 (HBV; HCV)
Liver tissue biopsy sample from patients with Hepatitis B and C infection related hepatocellular carcinoma (HCC) after resection.
Control normal liver tissue
Normal, non-tumor liver tissue.

HCC study 9 (HCV) / normal liver tissue

Relative Expression (log2-ratio):-4.682233
Number of Samples:9 / 10
Experimental HCC study 9 (HCV)
Liver tissue biopsy sample from patients with Hepatitis C infection related hepatocellular carcinoma (HCC) after resection.
Control normal liver tissue
Normal, non-tumor liver tissue.

HCC study 9 (alcohol) / normal liver tissue

Relative Expression (log2-ratio):-4.6799307
Number of Samples:24 / 10
Experimental HCC study 9 (alcohol)
Liver tissue biopsy sample from patients with alcohol abuse related hepatocellular carcinoma (HCC) after resection.
Control normal liver tissue
Normal, non-tumor liver tissue.

HCC study 9 (HBV) / normal liver tissue

Relative Expression (log2-ratio):-4.578867
Number of Samples:10 / 10
Experimental HCC study 9 (HBV)
Liver tissue biopsy sample from patients with Hepatitis B infection related hepatocellular carcinoma (HCC) after resection.
Control normal liver tissue
Normal, non-tumor liver tissue.