TOP TEN perturbations for 1108_s_at (Homo sapiens)
Organism: Homo sapiens
Gene: 1108_s_at
Selected probe(set): 205977_s_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 1108_s_at (205977_s_at) across 6674 perturbations tested by GENEVESTIGATOR:
stem cell differentiation study 59 (iDRG; 9d) / normal embryonic stem cell sample (WA09)
Relative Expression (log2-ratio):-4.3589735Number of Samples:4 / 4
Experimental | stem cell differentiation study 59 (iDRG; 9d) |
Immature dorsal root ganglia neurons (iDRGs) obtained by differentiation of WA09 embryonic stem cells. WA09 cells were differentiated for 8 days and subsequently cryopreserved. After thawing, cells were further differentiated for 1 day. Further details are described in the paper. | |
Control | normal embryonic stem cell sample (WA09) |
Undifferentiated WA09 embryonic stem cell samples. |
stem cell differentiation study 59 (iDRG; 15d) / normal embryonic stem cell sample (WA09)
Relative Expression (log2-ratio):-4.3588057Number of Samples:4 / 4
Experimental | stem cell differentiation study 59 (iDRG; 15d) |
Immature dorsal root ganglia neurons (iDRGs) obtained by differentiation of WA09 embryonic stem cells. WA09 cells were differentiated for 8 days and subsequently cryopreserved. After thawing, cells were further differentiated for 7 days. Further details are described in the paper. | |
Control | normal embryonic stem cell sample (WA09) |
Undifferentiated WA09 embryonic stem cell samples. |
stem cell differentiation study 59 (iDRG; 12d) / normal embryonic stem cell sample (WA09)
Relative Expression (log2-ratio):-4.17649Number of Samples:4 / 4
Experimental | stem cell differentiation study 59 (iDRG; 12d) |
Immature dorsal root ganglia neurons (iDRGs) obtained by differentiation of WA09 embryonic stem cells. WA09 cells were differentiated for 8 days and subsequently cryopreserved. After thawing, cells were further differentiated for 4 days. Further details are described in the paper. | |
Control | normal embryonic stem cell sample (WA09) |
Undifferentiated WA09 embryonic stem cell samples. |
stem cell differentiation study 59 (8d) / normal embryonic stem cell sample (WA09)
Relative Expression (log2-ratio):-4.0650406Number of Samples:4 / 4
Experimental | stem cell differentiation study 59 (8d) |
WA09 embryonic stem cell samples differentiated for 8 days. Further details are described in the paper. | |
Control | normal embryonic stem cell sample (WA09) |
Undifferentiated WA09 embryonic stem cell samples. |
stem cell differentiation study 41 (T3pi) / undifferentiated hES-T3 cell sample
Relative Expression (log2-ratio):-3.4021082Number of Samples:2 / 3
Experimental | stem cell differentiation study 41 (T3pi) |
Sample of pancreatic islet-like cell clusters differentiated from human embryonic stem cells T3 with female karyotype. | |
Control | undifferentiated hES-T3 cell sample |
Undifferentiated human embryonic stem cells T3. |
hepatocyte (ESC) / Hep-G2
Relative Expression (log2-ratio):2.4607954Number of Samples:8 / 9
Experimental | hepatocyte (ESC) |
Hepatocyte-like cells differentiated from embryonic stem cells (ESC) | |
Control | Hep-G2 |
Human primary cancer cell line derived from the liver of a patient with hepatocellular carcinoma. Synonyms:HEP-G2; Hep G2; HEP G2; HepG2; HEPG2 Cellosaurus code: |
dengue fever study 10 (DHF) / normal naive CD8 T cell sample
Relative Expression (log2-ratio):-2.2397137Number of Samples:2 / 5
Experimental | dengue fever study 10 (DHF) |
Activated CD8 T cells derived from peripheral blood mononuclear cells (PBMCs) of Thai individuals with Dengue hemorrhagic fever (DF) characterized by the WHO 1997. FACS-sorted CD3+, CD8+, HLA_DR+, and CD38+ effector CD8 T subtype cells were used for analysis. | |
Control | normal naive CD8 T cell sample |
Normal naive CD8 T cells derived from peripheral blood mononuclear cells (PBMCs) of healthy Thai individuals. FACS-sorted CD3+, CD8+, CD45RA+, and CCR7+ naive CD8 T subtype cells were used for analysis. |
TGF-β study 12 / untreated NCI-H358 cell sample
Relative Expression (log2-ratio):-2.1797638Number of Samples:3 / 3
Experimental | TGF-β study 12 |
NCI-H358 cells were cultured for 2-3 weeks in the presence of 2ng/ml of TGF-β, to induce epithelial-mesenchymal transition (EMT). 24 hours prior analysis cells were re-seeded without TGF-β. | |
Control | untreated NCI-H358 cell sample |
NCI-H358 cells grown in standard media. |
follicular lymphoma study 2 / tonsillar CD8 T-cell sample
Relative Expression (log2-ratio):-1.9788055Number of Samples:8 / 7
Experimental | follicular lymphoma study 2 |
CD8+ tumor infiltrating T-cells were isolated by FACS from cryopreserved single cell suspension of lymph node biopsies from treatment naive patients with follicular lymphoma. The cells were characterized as CD3+ / CD8+ / CD19-, with > 96% purity and < 2% B-cell contamination. | |
Control | tonsillar CD8 T-cell sample |
CD8+ tonsillar T-cells were isolated by FACS from a single cell suspension from reactive tonsils. The cells were characterized as CD3+ / CD8+ / CD19-, with > 96% purity and < 2% B-cell contamination. |
lung cancer study 1 (PDX; pseudosarcomatous carcinoma; primary) / lung cancer study 1 (PDX; basaloid carcinoma; primary)
Relative Expression (log2-ratio):-1.9677172Number of Samples:4 / 3
Experimental | lung cancer study 1 (PDX; pseudosarcomatous carcinoma; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary pseudosarcomatous carcinoma of the lung (subcutaneously implanted). | |
Control | lung cancer study 1 (PDX; basaloid carcinoma; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary basaloid carcinoma of the lung (subcutaneously implanted). |