TOP TEN perturbations for 11759712_at (Homo sapiens)

Organism: Homo sapiens
Gene: 11759712_at
Selected probe(set): 201048_x_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 11759712_at (201048_x_at) across 5880 perturbations tested by GENEVESTIGATOR:

glioma study 16 (LN-319) / normal astrocyte sample

Relative Expression (log2-ratio):3.0211916
Number of Samples:2 / 3
Experimental glioma study 16 (LN-319)
Human glioma cell line LN319 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37°C and 5% CO2.
Control normal astrocyte sample
Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations.

glioma study 16 (LN-215) / normal astrocyte sample

Relative Expression (log2-ratio):2.9620047
Number of Samples:2 / 3
Experimental glioma study 16 (LN-215)
Human glioma cell line LN215 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37°C and 5% CO2.
Control normal astrocyte sample
Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations.

glioma study 16 (LN-18) / normal astrocyte sample

Relative Expression (log2-ratio):2.852765
Number of Samples:2 / 3
Experimental glioma study 16 (LN-18)
Human glioma cell line LN018 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37C and 5% CO2.
Control normal astrocyte sample
Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations.

stem cell differentiation study 41 (T3pi) / stem cell differentiation study 41 (hES-T3 EB)

Relative Expression (log2-ratio):2.713337
Number of Samples:2 / 2
Experimental stem cell differentiation study 41 (T3pi)
Sample of pancreatic islet-like cell clusters differentiated from human embryonic stem cells T3 with female karyotype.
Control stem cell differentiation study 41 (hES-T3 EB)
Sample of embryonic bodies (EB) differentiated from human embryonic stem cells T3 with female karyotype.

basal cell carcinoma study 3 / normal epidermal keratinocytes

Relative Expression (log2-ratio):-2.6324406
Number of Samples:4 / 2
Experimental basal cell carcinoma study 3
Primary tumor tissue from the eyelid of patients with basal cell carcinoma (BCC).
Control normal epidermal keratinocytes
Normal human epidermal keratinocytes (NHEK) (Kurabo Ind., Ltd., Osaka, Japan) cultured in HuMedia-KB2 medium at 37°C in humidified air containing 5% CO2.

glioma study 16 (LN-229) / normal astrocyte sample

Relative Expression (log2-ratio):2.6298895
Number of Samples:2 / 3
Experimental glioma study 16 (LN-229)
Human glioma cell line LN229 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37°C and 5% CO2.
Control normal astrocyte sample
Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations.

glioma study 16 (BS-149) / normal astrocyte sample

Relative Expression (log2-ratio):2.5531197
Number of Samples:2 / 3
Experimental glioma study 16 (BS-149)
Human glioma cell line BS149 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37°C and 5% CO2.
Control normal astrocyte sample
Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations.

adrenal gland cancer study 4 / normal adrenal cortex tissue

Relative Expression (log2-ratio):2.4846191
Number of Samples:43 / 4
Experimental adrenal gland cancer study 4
Primary tumor tissue samples of the adrenal cortex from patients with adrenocortical carcinoma (ACC).
Control normal adrenal cortex tissue
Histological normal adrenal gland cortical tissue samples derived after autopsy.

ulcerative colitis study 55 (dysplasia) / normal descending colonic mucosa tissue

Relative Expression (log2-ratio):-2.2787313
Number of Samples:6 / 15
Experimental ulcerative colitis study 55 (dysplasia)
Descending colonic mucosal biopsies from dysplasia obtained from patients with ulcerative colitis (UC). Patients characteristics: Age (median IQR): 49 (28); Years with disease (<10 yr/>10 yr): 2/4; Mayo score (median IQR): 1.5 (5); Mayo endoscopic score (median IQR): 0.5 (2); Low-grade/high-grade dysplasia: 5/1; 4 patients received daily medication.
Control normal descending colonic mucosa tissue
Descending colonic mucosal biopsies obtained from controls. Subjects characteristics: Age (median IQR): 52 (34); Smoking/nonsmoking: 2/13.

ulcerative colitis study 55 (left-sided colitis) / ulcerative colitis study 55 (dysplasia)

Relative Expression (log2-ratio):2.2505074
Number of Samples:20 / 6
Experimental ulcerative colitis study 55 (left-sided colitis)
Descending colonic mucosal biopsies obtained from patients with left-sided ulcerative colitis (UC). Patients characteristics: Age (median IQR): 42 (30); Years with disease (<10 yr/>10 yr): 13/7; Mayo score (median IQR): 6 (4); Mayo endoscopic score (median IQR): 2 (0); Smoking/nonsmoking: 3/17. 18 patients received daily medication.
Control ulcerative colitis study 55 (dysplasia)
Descending colonic mucosal biopsies from dysplasia obtained from patients with ulcerative colitis (UC). Patients characteristics: Age (median IQR): 49 (28); Years with disease (<10 yr/>10 yr): 2/4; Mayo score (median IQR): 1.5 (5); Mayo endoscopic score (median IQR): 0.5 (2); Low-grade/high-grade dysplasia: 5/1; 4 patients received daily medication.