Organism: Homo sapiens
Gene: 1519_at
Selected probe(set): 201328_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 1519_at (201328_at) across 6540 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):-4.320383
Number of Samples:6 / 12

Experimental	IL-4; GM-CSF study 1 (late)
	Monocytes, cultured with vehicle (DMSO/ethanol) and 500 U/ml IL-4 and 800 U/ml GM-CSF for 5 days. Cytokine treatment was repeated at day 3.
Control	untreated monocyte sample
	Freshly isolated human monocytes from healthy donors.

Relative Expression (log2-ratio):3.6950245
Number of Samples:2 / 9

Experimental	expO skin cancer study 1 (squamous cell carcinoma, NOS; metastatic)
	Metastatic tumor tissue samples obtained from patients with primary squamous cell carcinoma (NOS) of the skin.
Control	expO skin cancer study 1 (malignant melanoma, NOS; metastatic)
	Metastatic tumor tissue samples obtained from patients with primary malignant melanoma (NOS) of the skin.

Relative Expression (log2-ratio):-3.5535145
Number of Samples:20 / 12

Experimental	breast cancer study 5
	Breast non-BLC (sporadic basal-like cancer) tumor samples.
Control	normal organelle sample
	Normal organelle samples.

Relative Expression (log2-ratio):-3.5351753
Number of Samples:2 / 2

Experimental	bone cancer study 1 (PDX; chondroblastic osteosarcoma; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary chondroblastic osteosarcoma of the bone (subcutaneously implanted).
Control	bone cancer study 1 (PDX; myxoid chondrosarcoma; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary myxoid chondrosarcoma of the bone (subcutaneously implanted).

Relative Expression (log2-ratio):-3.466363
Number of Samples:7 / 3

Experimental	Langerhans cell histiocytosis study 1
	Langerhans cell histiocytes (LCH) were isolated from LCH lesions of patients undergoing surgery. All patients had single system disease, five patients had bone lesion, one had skin lesion and one had mucosal manifestation. Langerhans cells histiocytes were purified by FACS as CD1a+ / CD270 + population with > 95% purity.
Control	normal myeloid dendritic cell sample
	Normal myeloid dendritic cells were isolated from peripheral blood of healthy adult donors. Myeloid dendritic cells were defined as HLA-DR+ / CD11c + / BDCA1+ / BDCA3- population.

Relative Expression (log2-ratio):-3.4306297
Number of Samples:2 / 2

Experimental	bone cancer study 1 (PDX; chondroblastic osteosarcoma; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary chondroblastic osteosarcoma of the bone (subcutaneously implanted).
Control	bone cancer study 1 (PDX; osteosarcoma, NOS; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary osteosarcoma, NOS of the bone (subcutaneously implanted).

Relative Expression (log2-ratio):3.4209185
Number of Samples:10 / 10

Experimental	ZSTK474 inhibitor (10uM); GM-CSF (1ng/ml) study 1
	Primary neutrophils isolated from blood samples of healthy volunteers purified over discontinuous plasma-percoll gradients. Neutrophils were treated with pan phosphoinositide 3-kinase (PI3K) inhibitor ZSTK474 (10uM) and granulocyte macrophage-colony stimulating factor (rhGM-CSF; 1ng/ml) for 6h. ATC code:---
Control	ZSTK474 study 1 (10uM)
	Primary neutrophils isolated from blood samples of healthy volunteers purified over discontinuous plasma-percoll gradients. Neutrophils were treated with 10uM pan phosphoinositide 3-kinase (PI3K) inhibitor ZSTK434 for 6h. ATC code:---

Relative Expression (log2-ratio):-3.4168034
Number of Samples:2 / 2

Experimental	ALL study 3 (8d)
	Peripheral blood samples from children with de novo acute lymphoblastic leukemia. Samples were taken 8 days after remission-induction therapy (RIT).
Control	ALL study 3 (0d)
	Peripheral blood samples from children with de novo acute lymphoblastic leukemia. Samples were taken before remission-induction therapy (RIT).

Relative Expression (log2-ratio):3.316657
Number of Samples:4 / 4

Experimental	OPM-1
	Human primary cancer cell line derived from the peripheral blood of a patient with multiple myeloma. Dexamethasone-resistant. Synonyms:OPM1 Cellosaurus code:
Control	MM1.S
	Human primary cancer cell line derived from the peripheral blood of a patient with multiple myeloma. Dexamethasone-sensitive. Parental cell line:: MM.1 Synonyms:MM.1S; MM1-S; MM-1S; MM1S Cellosaurus code:

Relative Expression (log2-ratio):-3.2371073
Number of Samples:3 / 3

Experimental	echinomycin study 1
	Echinomycin (100nM; 2h) treated human astroglioma (U251) cells, stimulated with deferoxamine (DFO; 300mM; 16h). ATC code:---
Control	deferoxamine study 5
	Untreated human astroglioma (U251) cells, stimulated with deferoxamine (DFO; 300mM; 16h). ATC code: