TOP TEN perturbations for 1538_s_at (Homo sapiens)

Organism: Homo sapiens
Gene: 1538_s_at
Selected probe(set): 207849_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 1538_s_at (207849_at) across 6537 perturbations tested by GENEVESTIGATOR:

T-cell activation study 1 / quiescent CD4+ T-cell sample

Relative Expression (log2-ratio):9.044381
Number of Samples:2 / 2
Experimental T-cell activation study 1
CD4+ T-cell samples derived from PBMC´s of HIV-seronegative donors were activated with plate bound CD3 (1ug/ml) and soluble CD28 (50ng/ml) for 1 day.
Control quiescent CD4+ T-cell sample
Quiescent CD4+ T-cell samples derived from PBMC´s of HIV-seronegative donors.

T-cell activation study 3 / resting CD4 T-lymphocyte (crude fraction) sample

Relative Expression (log2-ratio):8.823296
Number of Samples:2 / 2
Experimental T-cell activation study 3
CD4+ T-cell samples prepared from crude lymphocyte fraction. Cells were activated with anti-CD3/28 beads for 18hrs.
Control resting CD4 T-lymphocyte (crude fraction) sample
Resting CD4 T-lymphocytes prepared from crude lymphocyte fraction.

T-helper activation study 1 (180min) / unstimulated helper T-cell sample

Relative Expression (log2-ratio):8.28521
Number of Samples:2 / 2
Experimental T-helper activation study 1 (180min)
Alloantigen specific helper T-cells were stimulated for 180min with anti-CD3/anti-CD28/IL-2 (100U/ml). T-helper cells were sorted as CD4+ CD25- cells from peripheral blood of healthy donors.
Control unstimulated helper T-cell sample
Unstimulated alloantigen specific helper T-cell sample derived from sorted CD4+ CD25- cells from peripheral blood of healthy donors.

T-helper activation study 1 (160min) / unstimulated helper T-cell sample

Relative Expression (log2-ratio):8.246183
Number of Samples:2 / 2
Experimental T-helper activation study 1 (160min)
Alloantigen specific helper T-cells were stimulated for 160min with anti-CD3/anti-CD28/IL-2 (100U/ml). T-helper cells were sorted as CD4+ CD25- cells from peripheral blood of healthy donors.
Control unstimulated helper T-cell sample
Unstimulated alloantigen specific helper T-cell sample derived from sorted CD4+ CD25- cells from peripheral blood of healthy donors.

T-helper activation study 1 (260min) / unstimulated helper T-cell sample

Relative Expression (log2-ratio):8.2126465
Number of Samples:2 / 2
Experimental T-helper activation study 1 (260min)
Alloantigen specific helper T-cells were stimulated for 260min with anti-CD3/anti-CD28/IL-2 (100U/ml). T-helper cells were sorted as CD4+ CD25- cells from peripheral blood of healthy donors.
Control unstimulated helper T-cell sample
Unstimulated alloantigen specific helper T-cell sample derived from sorted CD4+ CD25- cells from peripheral blood of healthy donors.

T-helper activation study 1 (140min) / unstimulated helper T-cell sample

Relative Expression (log2-ratio):8.123632
Number of Samples:2 / 2
Experimental T-helper activation study 1 (140min)
Alloantigen specific helper T-cells were stimulated for 140min with anti-CD3/anti-CD28/IL-2 (100U/ml). T-helper cells were sorted as CD4+ CD25- cells from peripheral blood of healthy donors.
Control unstimulated helper T-cell sample
Unstimulated alloantigen specific helper T-cell sample derived from sorted CD4+ CD25- cells from peripheral blood of healthy donors.

T-helper activation study 1 (220min) / unstimulated helper T-cell sample

Relative Expression (log2-ratio):8.10375
Number of Samples:2 / 2
Experimental T-helper activation study 1 (220min)
Alloantigen specific helper T-cells were stimulated for 220min with anti-CD3/anti-CD28/IL-2 (100U/ml). T-helper cells were sorted as CD4+ CD25- cells from peripheral blood of healthy donors.
Control unstimulated helper T-cell sample
Unstimulated alloantigen specific helper T-cell sample derived from sorted CD4+ CD25- cells from peripheral blood of healthy donors.

T-helper activation study 1 (200min) / unstimulated helper T-cell sample

Relative Expression (log2-ratio):8.10162
Number of Samples:2 / 2
Experimental T-helper activation study 1 (200min)
Alloantigen specific helper T-cells were stimulated for 200min with anti-CD3/anti-CD28/IL-2 (100U/ml). T-helper cells were sorted as CD4+ CD25- cells from peripheral blood of healthy donors.
Control unstimulated helper T-cell sample
Unstimulated alloantigen specific helper T-cell sample derived from sorted CD4+ CD25- cells from peripheral blood of healthy donors.

T-helper activation study 1 (240min) / unstimulated helper T-cell sample

Relative Expression (log2-ratio):7.9838257
Number of Samples:2 / 2
Experimental T-helper activation study 1 (240min)
Alloantigen specific helper T-cells were stimulated for 240min with anti-CD3/anti-CD28/IL-2 (100U/ml). T-helper cells were sorted as CD4+ CD25- cells from peripheral blood of healthy donors.
Control unstimulated helper T-cell sample
Unstimulated alloantigen specific helper T-cell sample derived from sorted CD4+ CD25- cells from peripheral blood of healthy donors.

T-helper activation study 1 (120min) / unstimulated helper T-cell sample

Relative Expression (log2-ratio):7.9753036
Number of Samples:2 / 2
Experimental T-helper activation study 1 (120min)
Alloantigen specific helper T-cells were stimulated for 120min with anti-CD3/anti-CD28/IL-2 (100U/ml). T-helper cells were sorted as CD4+ CD25- cells from peripheral blood of healthy donors.
Control unstimulated helper T-cell sample
Unstimulated alloantigen specific helper T-cell sample derived from sorted CD4+ CD25- cells from peripheral blood of healthy donors.