Organism: Homo sapiens
Gene: 1552263_at
Selected probe(set): 224621_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 1552263_at (224621_at) across 6672 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):-2.5473337
Number of Samples:6 / 6

Experimental	MAPK1 depletion study 1
	RNAi-mediated gene knockdown of MAPK1 in colorectal cancer cell line SW-480.
Control	control vector transfected SW-480 cell sample
	SW-480 colorectal cell line sample transduced with empty vector pLKO.

Relative Expression (log2-ratio):-2.378952
Number of Samples:6 / 3

Experimental	MAPK1 depletion study 1
	RNAi-mediated gene knockdown of MAPK1 in colorectal cancer cell line SW-480.
Control	normal SW-480 cell sample
	Non-transduced SW-480 colorectal cell line sample.

Relative Expression (log2-ratio):-2.3222494
Number of Samples:6 / 6

Experimental	MAPK1 depletion study 1
	RNAi-mediated gene knockdown of MAPK1 in colorectal cancer cell line SW-480.
Control	mock transfected SW-480 cell sample
	SW-480 colorectal cell line sample transduced with non-targeting pLKO_NonTarget vector.

Relative Expression (log2-ratio):-2.3220978
Number of Samples:2 / 2

Experimental	zalypsis study 2
	OPM1 multiple myeloma cells treated in vitro with zalypsis (5 nM), a novel marine-derived compound with potent antimyeloma activity. Cells were harvested at the beginning of induction of cell death (15-20% cell death as assessed by Annexin V-FITC staining). ATC code:---
Control	untreated OPM1 cell sample
	OPM1 multiple myeloma cells untreated.

Relative Expression (log2-ratio):-2.029335
Number of Samples:4 / 9

Experimental	medulloblastoma study 2
	Primary tumor tissue sample from the infratentorial brain of pediatric patients with large-cell anaplastic medulloblastoma.
Control	non-tumor brain tissue
	Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor.

Relative Expression (log2-ratio):-1.8945093
Number of Samples:3 / 3

Experimental	peptidoglycan study 1
	Healthy neonatal neutrophils with ≥ 99% purity isolated from cord blood samples collected after normal, full-term, vaginal delivery treated with peptidoglycan isolated from S. aureus (10 ug/ml) for 4 hours.
Control	mock treated neonatal neutrophils
	Healthy neonatal neutrophils with ≥ 99% purity isolated from cord blood samples collected after normal, full-term, vaginal delivery mock treated for 4 hours.

Relative Expression (log2-ratio):-1.8912344
Number of Samples:3 / 3

Experimental	kidney transplantation study 16 (2 week)
	CD56+ natural killer cell samples derived from kidney transplant patients 2 weeks post-transplantation. Samples were collected 2 week after transplantation and administration of immunosuppressive therapy (day 1-4: methylprednisolone (60 mg); 3 doses: rabbit polyclonal anti-thymocyte globulin (ThymoglobulinH; 6 mg/kg); mycophenolate mofetil (CellCeptH); and tacrolimus (PrografH).
Control	normal natural killer cell (CD56+) sample
	CD56+ natural killer cell samples derived from healthy control subjects.

Relative Expression (log2-ratio):-1.8887949
Number of Samples:2 / 2

Experimental	T-cell isolation study 11
	CD4+ resting memory T-cell were isolated from peripheral blood buffy coat of healthy donors after storage for 24 hours at 20°C. The cell fraction was first enriched via density gradient centrifugation with LSM 1077 Ficoll and than FACS sorted as CD3+/CD4+/CD45RO+/CD45RA- population.
Control	T-cell isolation study 6
	CD4+ resting memory T-cell were isolated from whole peripheral blood of healthy donors with no delay. The cell fraction was first enriched via density gradient centrifugation with LSM 1077 Ficoll and than FACS sorted as CD3+/CD4+/CD45RO+/CD45RA- population.

Relative Expression (log2-ratio):-1.8596115
Number of Samples:18 / 12

Experimental	ovarian tumor study 13
	Human epithelial tumor cell samples from the ovary of patients with serous adenocarcinoma. Samples were derived by laser capture microdissection (LCM).
Control	normal ovarian surface epithelial cell sample
	Human epithelial cell samples from histopathological normal and non-cancerous ovary tissue from healthy donors. Samples were derived by cell surface brushing.

Relative Expression (log2-ratio):-1.8145704
Number of Samples:2 / 3

Experimental	glioma study 16 (LN-215)
	Human glioma cell line LN215 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37°C and 5% CO2.
Control	normal astrocyte sample
	Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations.