TOP TEN perturbations for 1552266_at (Homo sapiens)
Organism: Homo sapiens
Gene: 1552266_at
Selected probe(set): 1552266_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 1552266_at (1552266_at) across 6593 perturbations tested by GENEVESTIGATOR:
male infertility study 1 (juvenile; Ad-) / normal testicular lobules tissue (mJS10)
Relative Expression (log2-ratio):-5.443104Number of Samples:2 / 8
Experimental | male infertility study 1 (juvenile; Ad-) |
Human testicular lobules biopsy samples isolated from prepubescent patients with undescended testes. Testes of these children contained very low level of A-dark (Ad-) spermatogonial cells. | |
Control | normal testicular lobules tissue (mJS10) |
Biopsies of human testicular lobules isolated from fertile vasectomized adult men with normal spermatogenesis. Histological analysis classified samples as mJS10 (modified Johnsen score 10). |
male infertility study 1 (mJS2) / normal testicular lobules tissue (mJS10)
Relative Expression (log2-ratio):-5.1829147Number of Samples:7 / 8
Experimental | male infertility study 1 (mJS2) |
Human testicular lobules biopsy samples isolated from adult infertile patients whose seminiferous tubules contained almost exclusively Sertoli cells. Tissue samples were classified based on modified Johnsen score (mJS) as mJS2. | |
Control | normal testicular lobules tissue (mJS10) |
Biopsies of human testicular lobules isolated from fertile vasectomized adult men with normal spermatogenesis. Histological analysis classified samples as mJS10 (modified Johnsen score 10). |
male infertility study 1 (juvenile; Ad+) / normal testicular lobules tissue (mJS10)
Relative Expression (log2-ratio):-5.0124187Number of Samples:5 / 8
Experimental | male infertility study 1 (juvenile; Ad+) |
Human testicular lobules biopsy samples isolated from prepubescent patients with undescended testes. Testes of these children contained typical level of A-dark (Ad+) spermatogonial cells. | |
Control | normal testicular lobules tissue (mJS10) |
Biopsies of human testicular lobules isolated from fertile vasectomized adult men with normal spermatogenesis. Histological analysis classified samples as mJS10 (modified Johnsen score 10). |
male infertility study 1 (mJS3) / normal testicular lobules tissue (mJS10)
Relative Expression (log2-ratio):-4.723487Number of Samples:3 / 8
Experimental | male infertility study 1 (mJS3) |
Human testicular lobules biopsy samples isolated from adult infertile patients whose seminiferous tubules contained Sertoli cells but rarely spermatogonia. Tissue samples were classified based on modified Johnsen score (mJS) as mJS3. | |
Control | normal testicular lobules tissue (mJS10) |
Biopsies of human testicular lobules isolated from fertile vasectomized adult men with normal spermatogenesis. Histological analysis classified samples as mJS10 (modified Johnsen score 10). |
male infertility study 1 (mJS5) / normal testicular lobules tissue (mJS10)
Relative Expression (log2-ratio):-4.6945934Number of Samples:8 / 8
Experimental | male infertility study 1 (mJS5) |
Human testicular lobules biopsy samples isolated from adult infertile patients whose seminiferous tubules contained spermatocytes but no spermatids. Tissue samples were classified based on modified Johnsen score (mJS) as mJS5. | |
Control | normal testicular lobules tissue (mJS10) |
Biopsies of human testicular lobules isolated from fertile vasectomized adult men with normal spermatogenesis. Histological analysis classified samples as mJS10 (modified Johnsen score 10). |
male infertility study 1 (mJS8) / male infertility study 1 (mJS2)
Relative Expression (log2-ratio):4.059746Number of Samples:7 / 7
Experimental | male infertility study 1 (mJS8) |
Human testicular lobules biopsy samples isolated from adult infertile patients whose seminiferous tubules contained many early and elongated but only few mature spermatids. Tissue samples were classified based on modified Johnsen score (mJS) as mJS8. | |
Control | male infertility study 1 (mJS2) |
Human testicular lobules biopsy samples isolated from adult infertile patients whose seminiferous tubules contained almost exclusively Sertoli cells. Tissue samples were classified based on modified Johnsen score (mJS) as mJS2. |
male infertility study 1 (mJS8) / male infertility study 1 (mJS3)
Relative Expression (log2-ratio):3.600318Number of Samples:7 / 3
Experimental | male infertility study 1 (mJS8) |
Human testicular lobules biopsy samples isolated from adult infertile patients whose seminiferous tubules contained many early and elongated but only few mature spermatids. Tissue samples were classified based on modified Johnsen score (mJS) as mJS8. | |
Control | male infertility study 1 (mJS3) |
Human testicular lobules biopsy samples isolated from adult infertile patients whose seminiferous tubules contained Sertoli cells but rarely spermatogonia. Tissue samples were classified based on modified Johnsen score (mJS) as mJS3. |
male infertility study 1 (mJS7) / male infertility study 1 (mJS2)
Relative Expression (log2-ratio):3.597268Number of Samples:4 / 7
Experimental | male infertility study 1 (mJS7) |
Human testicular lobules biopsy samples isolated from adult infertile patients whose seminiferous tubules contained early but no late spermatids. Tissue samples were classified based on modified Johnsen score (mJS) as mJS7. | |
Control | male infertility study 1 (mJS2) |
Human testicular lobules biopsy samples isolated from adult infertile patients whose seminiferous tubules contained almost exclusively Sertoli cells. Tissue samples were classified based on modified Johnsen score (mJS) as mJS2. |
male infertility study 1 (mJS8) / male infertility study 1 (mJS5)
Relative Expression (log2-ratio):3.5714245Number of Samples:7 / 8
Experimental | male infertility study 1 (mJS8) |
Human testicular lobules biopsy samples isolated from adult infertile patients whose seminiferous tubules contained many early and elongated but only few mature spermatids. Tissue samples were classified based on modified Johnsen score (mJS) as mJS8. | |
Control | male infertility study 1 (mJS5) |
Human testicular lobules biopsy samples isolated from adult infertile patients whose seminiferous tubules contained spermatocytes but no spermatids. Tissue samples were classified based on modified Johnsen score (mJS) as mJS5. |
male infertility study 1 (mJS7) / male infertility study 1 (mJS3)
Relative Expression (log2-ratio):3.1378403Number of Samples:4 / 3
Experimental | male infertility study 1 (mJS7) |
Human testicular lobules biopsy samples isolated from adult infertile patients whose seminiferous tubules contained early but no late spermatids. Tissue samples were classified based on modified Johnsen score (mJS) as mJS7. | |
Control | male infertility study 1 (mJS3) |
Human testicular lobules biopsy samples isolated from adult infertile patients whose seminiferous tubules contained Sertoli cells but rarely spermatogonia. Tissue samples were classified based on modified Johnsen score (mJS) as mJS3. |