Organism: Homo sapiens
Gene: 1552302_at
Selected probe(set): 1552302_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 1552302_at (1552302_at) across 6593 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):3.2756343
Number of Samples:9 / 12

Experimental	Hep-G2
	Human primary cancer cell line derived from the liver of a patient with hepatocellular carcinoma. Synonyms:HEP-G2; Hep G2; HEP G2; HepG2; HEPG2 Cellosaurus code:
Control	HepaRG
	Immortalized cancer cell line derived from female patient with hepatocellular carcinoma. Cells can be induced to differentiate into hepatocyte-like cells by exposure to DMSO. Synonyms:Hepa-RG Cellosaurus code:

Relative Expression (log2-ratio):3.2428083
Number of Samples:6 / 12

Experimental	IL-4; GM-CSF study 1 (early)
	Monocytes, cultured with vehicle (DMSO/ethanol) and 500 U/ml IL-4 and 800 U/ml GM-CSF for 6 hours.
Control	untreated monocyte sample
	Freshly isolated human monocytes from healthy donors.

Relative Expression (log2-ratio):-3.0736065
Number of Samples:4 / 3

Experimental	renal cell carcinoma study 6 (chromophobe type)
	Tumor tissue samples from the kidney of patients with chromophobe renal cell carcinoma (cRCC).
Control	normal kidney tissue
	Normal adult kidney tissue samples.

Relative Expression (log2-ratio):-3.013091
Number of Samples:4 / 3

Experimental	oxyphilic adenoma study 1
	Tumor tissue samples from the kidney of patients with oxyphilic adenoma (renal oncocytoma).
Control	normal kidney tissue
	Normal adult kidney tissue samples.

Relative Expression (log2-ratio):-2.9688063
Number of Samples:4 / 3

Experimental	nephroblastoma study 2
	Tumor tissue samples from the kidney of patients with Wilms’ tumor.
Control	normal kidney tissue
	Normal adult kidney tissue samples.

Relative Expression (log2-ratio):-2.8189254
Number of Samples:6 / 5

Experimental	connective/soft tissue cancer study 1 (PDX; connective and soft tissue, synovial sarcoma, spindle cell; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary connective and soft tissue, synovial sarcoma, spindle cell of the soft tissue (subcutaneously implanted).
Control	connective/soft tissue cancer study 1 (PDX; connective and soft tissue, fibromyxosarcoma; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary connective and soft tissue, fibromyxosarcoma of the soft tissue (subcutaneously implanted).

Relative Expression (log2-ratio):2.6495876
Number of Samples:2 / 5

Experimental	kidney transplantation study 15 (8 week)
	CD14+ monocyte samples derived from kidney transplant patients 8 weeks post-transplantation. Samples were collected 8 week after transplantation and administration of immunosuppressive therapy (day 1-4: methylprednisolone (60 mg); 3 doses: rabbit polyclonal anti-thymocyte globulin (ThymoglobulinH; 6 mg/kg); mycophenolate mofetil (CellCeptH); and tacrolimus (PrografH).
Control	normal monocyte (CD14+) sample
	CD14+ monocyte samples derived from healthy control subjects.

Relative Expression (log2-ratio):2.63272
Number of Samples:3 / 11

Experimental	HCC study 20 (CDX; Hep-G2; ectopic)
	Tumor tissue biopsy samples from Hep-G2 cell line-derived xenograft (CDX) ectopically generated in SCID mice by injecting hepatocellular carcinoma cells subcutaneously. In order to establish ectopic models, cells were injected subcutaneously into the flank regions. The mice were euthanized after two weeks.
Control	HCC study 20 (PDX; ectopic)
	Tumor tissue biopsy samples from patient-derived xenograft (PDX) sample ectopically generated in SCID mice by injecting hepatocellular carcinoma cells subcutaneously. Donor tumor tissue was obtained intraoperatively during liver resection from three patients. All three patients had hepatocellular carcinoma confirmed by histology. In order to establish ectopic models, cells were injected subcutaneously into the flank regions. The mice were euthanized after two weeks.

Relative Expression (log2-ratio):2.5830765
Number of Samples:40 / 74

Experimental	B-ALL study 1 (hyperdiploid)
	Bone marrow samples of patients with hyperdiploid B-ALL (hyperdiploid karyotype).
Control	normal bone marrow sample
	Non-leukemic and healthy bone marrow sample.

Relative Expression (log2-ratio):2.573063
Number of Samples:4 / 4

Experimental	dendritic cell study 6 (gardiquimod; RN486)
	Plasmacytoid dendritic cells (pDCs) collected from blood of healthy donors and treated with gardiquimod (TLR7 agonist) and RN486 (Bruton’s tyrosine kinase; BTK inhibitor) for 3 hours. pDCs were sorted as CD303+, CD123+, CD45+, CD69+, CD40+, CD86+.
Control	dendritic cell study 6 (CpG A; RN486)
	Plasmacytoid dendritic cells (pDCs) collected from blood of healthy donors and treated with CpG-A ODN2216 Class A (TLR9 agonist) and RN486 (Bruton’s tyrosine kinase; BTK inhibitor) for 3 hours. pDCs were sorted as CD303+, CD123+, CD45+, CD69+, CD40+, CD86+.