Organism: Homo sapiens
Gene: 1552445_a_at
Selected probe(set): 1552445_a_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 1552445_a_at (1552445_a_at) across 6540 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):4.4074736
Number of Samples:8 / 7

Experimental	male infertility study 1 (mJS5)
	Human testicular lobules biopsy samples isolated from adult infertile patients whose seminiferous tubules contained spermatocytes but no spermatids. Tissue samples were classified based on modified Johnsen score (mJS) as mJS5.
Control	male infertility study 1 (mJS2)
	Human testicular lobules biopsy samples isolated from adult infertile patients whose seminiferous tubules contained almost exclusively Sertoli cells. Tissue samples were classified based on modified Johnsen score (mJS) as mJS2.

Relative Expression (log2-ratio):4.155566
Number of Samples:7 / 7

Experimental	male infertility study 1 (mJS8)
	Human testicular lobules biopsy samples isolated from adult infertile patients whose seminiferous tubules contained many early and elongated but only few mature spermatids. Tissue samples were classified based on modified Johnsen score (mJS) as mJS8.
Control	male infertility study 1 (mJS2)
	Human testicular lobules biopsy samples isolated from adult infertile patients whose seminiferous tubules contained almost exclusively Sertoli cells. Tissue samples were classified based on modified Johnsen score (mJS) as mJS2.

Relative Expression (log2-ratio):3.9019165
Number of Samples:4 / 7

Experimental	male infertility study 1 (mJS7)
	Human testicular lobules biopsy samples isolated from adult infertile patients whose seminiferous tubules contained early but no late spermatids. Tissue samples were classified based on modified Johnsen score (mJS) as mJS7.
Control	male infertility study 1 (mJS2)
	Human testicular lobules biopsy samples isolated from adult infertile patients whose seminiferous tubules contained almost exclusively Sertoli cells. Tissue samples were classified based on modified Johnsen score (mJS) as mJS2.

Relative Expression (log2-ratio):-3.8081217
Number of Samples:7 / 8

Experimental	male infertility study 1 (mJS2)
	Human testicular lobules biopsy samples isolated from adult infertile patients whose seminiferous tubules contained almost exclusively Sertoli cells. Tissue samples were classified based on modified Johnsen score (mJS) as mJS2.
Control	normal testicular lobules tissue (mJS10)
	Biopsies of human testicular lobules isolated from fertile vasectomized adult men with normal spermatogenesis. Histological analysis classified samples as mJS10 (modified Johnsen score 10).

Relative Expression (log2-ratio):-3.4228287
Number of Samples:2 / 8

Experimental	male infertility study 1 (juvenile; Ad-)
	Human testicular lobules biopsy samples isolated from prepubescent patients with undescended testes. Testes of these children contained very low level of A-dark (Ad-) spermatogonial cells.
Control	normal testicular lobules tissue (mJS10)
	Biopsies of human testicular lobules isolated from fertile vasectomized adult men with normal spermatogenesis. Histological analysis classified samples as mJS10 (modified Johnsen score 10).

Relative Expression (log2-ratio):2.9420872
Number of Samples:3 / 3

Experimental	gefitinib study 2
	Gefitinib-resistant A431 (A431 GR) cells generated by growing parental cells in the presence of increasing concentrations of gefitinib up to 3 μM. Cells were selected and maintained in gefitinib (3μM). ATC code:
Control	wild type A431 cell sample
	A431 wild type cells.

Relative Expression (log2-ratio):2.862589
Number of Samples:5 / 2

Experimental	male infertility study 1 (juvenile; Ad+)
	Human testicular lobules biopsy samples isolated from prepubescent patients with undescended testes. Testes of these children contained typical level of A-dark (Ad+) spermatogonial cells.
Control	male infertility study 1 (juvenile; Ad-)
	Human testicular lobules biopsy samples isolated from prepubescent patients with undescended testes. Testes of these children contained very low level of A-dark (Ad-) spermatogonial cells.

Relative Expression (log2-ratio):2.429616
Number of Samples:8 / 3

Experimental	male infertility study 1 (mJS5)
	Human testicular lobules biopsy samples isolated from adult infertile patients whose seminiferous tubules contained spermatocytes but no spermatids. Tissue samples were classified based on modified Johnsen score (mJS) as mJS5.
Control	male infertility study 1 (mJS3)
	Human testicular lobules biopsy samples isolated from adult infertile patients whose seminiferous tubules contained Sertoli cells but rarely spermatogonia. Tissue samples were classified based on modified Johnsen score (mJS) as mJS3.

Relative Expression (log2-ratio):2.2651606
Number of Samples:2 / 2

Experimental	A431-PR
	Human primary cancer cell line derived from the skin of a 85 years old female patient with epidermoid carcinoma. Stably transduced with a small hairpin RNA targeting human PTEN, a tumor suppressor gene that is able to dephosphorylate phosphatidylinositol 3,4,5-trisphosphate, the product of phosphatidyl inositol 3-kinase. Parental cell line:: A-431 Synonyms:A431 PR Cellosaurus code:
Control	A-431
	Human primary cancer cell line derived from the skin of a 85 years old female patient with epidermoid carcinoma. Synonyms:A431 Cellosaurus code:

Relative Expression (log2-ratio):-2.1959276
Number of Samples:2 / 2

Experimental	bone cancer study 1 (PDX; chondroblastic osteosarcoma; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary chondroblastic osteosarcoma of the bone (subcutaneously implanted).
Control	bone cancer study 1 (PDX; osteosarcoma, NOS; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary osteosarcoma, NOS of the bone (subcutaneously implanted).