TOP TEN perturbations for 1552493_s_at (Homo sapiens)

Organism: Homo sapiens
Gene: 1552493_s_at
Selected probe(set): 1552493_s_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 1552493_s_at (1552493_s_at) across 6537 perturbations tested by GENEVESTIGATOR:

adrenal gland cancer study 4 / normal adrenal cortex tissue

Relative Expression (log2-ratio):-4.4826803
Number of Samples:43 / 4
Experimental adrenal gland cancer study 4
Primary tumor tissue samples of the adrenal cortex from patients with adrenocortical carcinoma (ACC).
Control normal adrenal cortex tissue
Histological normal adrenal gland cortical tissue samples derived after autopsy.

adrenal gland cancer study 5 (ACC) / AIMAH study 1

Relative Expression (log2-ratio):-3.117196
Number of Samples:34 / 10
Experimental adrenal gland cancer study 5 (ACC)
Primary tumor tissue samples of the adrenal cortex from patients with adrenocortical carcinoma (ACC).
Control AIMAH study 1
Adrenal gland tissue samples from patients with ACTH-independant macronodular adrenal hyperplasia (AIMAH).

adrenal gland cancer study 2 / normal adrenal cortex tissue

Relative Expression (log2-ratio):-2.9729633
Number of Samples:31 / 10
Experimental adrenal gland cancer study 2
Primary tumor tissue samples of the adrenal cortex from patients with adrenocortical carcinoma.
Control normal adrenal cortex tissue
Unaffected adrenal cortex tissue from control objects.

adrenal gland cancer study 5 (ACC) / normal adrenal cortex tissue

Relative Expression (log2-ratio):-2.9448128
Number of Samples:34 / 4
Experimental adrenal gland cancer study 5 (ACC)
Primary tumor tissue samples of the adrenal cortex from patients with adrenocortical carcinoma (ACC).
Control normal adrenal cortex tissue
Histological normal adrenal gland cortical tissue samples.

adrenal gland cancer study 2 / adrenal gland cancer study 1

Relative Expression (log2-ratio):-2.9195404
Number of Samples:31 / 22
Experimental adrenal gland cancer study 2
Primary tumor tissue samples of the adrenal cortex from patients with adrenocortical carcinoma.
Control adrenal gland cancer study 1
Primary tumor tissue samples of the adrenal cortex from patients with adrenocortical adenoma.

adrenal gland cancer study 5 (ACC) / adrenal gland cancer study 5 (ACA)

Relative Expression (log2-ratio):-2.7584076
Number of Samples:34 / 58
Experimental adrenal gland cancer study 5 (ACC)
Primary tumor tissue samples of the adrenal cortex from patients with adrenocortical carcinoma (ACC).
Control adrenal gland cancer study 5 (ACA)
Primary tumor tissue samples of the adrenal cortex from patients with adrenocortical adenoma (ACA).

adrenal gland cancer study 3 / normal adrenal cortex tissue

Relative Expression (log2-ratio):-1.9870443
Number of Samples:2 / 10
Experimental adrenal gland cancer study 3
Relapse tumor sample of the adrenal cortex from patients with recurrent adrenocortical carcinoma.
Control normal adrenal cortex tissue
Unaffected adrenal cortex tissue from control objects.

aldosterone-producing adenoma study 1 / normal adrenal gland tissue

Relative Expression (log2-ratio):-1.6477976
Number of Samples:9 / 5
Experimental aldosterone-producing adenoma study 1
Aldosterone-producing adenoma samples.
Control normal adrenal gland tissue
Normal adrenal gland samples.

glioma study 17 (anaplastic astrocytoma; A2B5+) / non-tumor oligodendrocyte progenitor cell sample (cortex)

Relative Expression (log2-ratio):-1.2811918
Number of Samples:2 / 3
Experimental glioma study 17 (anaplastic astrocytoma; A2B5+)
Oligodendrocyte progenitor cells (OPC) isolated from high grade anaplastic astrocytoma (grade III). OPC were isolated using magnetic-activated cell sorting (MACS) with antibodies against A2B5 antigen. Patients were 45 ± 18 years old.
Control non-tumor oligodendrocyte progenitor cell sample (cortex)
Oligodendrocyte progenitor cells (OPC) isolated from cortical tissue, which was obtained from patients with epilepsy, but without any manifested brain cancer. OPC were isolated using magnetic-activated cell sorting (MACS) with antibodies against A2B5 antigen.

glioma study 17 (astrocytoma; A2B5+) / non-tumor oligodendrocyte progenitor cell sample (cortex)

Relative Expression (log2-ratio):-1.2747121
Number of Samples:3 / 3
Experimental glioma study 17 (astrocytoma; A2B5+)
Oligodendrocyte progenitor cells (OPC) isolated from low grade astrocytoma (grade II). OPC were isolated using magnetic-activated cell sorting (MACS) with antibodies against A2B5 antigen. Patients were 36 ± 7 years old.
Control non-tumor oligodendrocyte progenitor cell sample (cortex)
Oligodendrocyte progenitor cells (OPC) isolated from cortical tissue, which was obtained from patients with epilepsy, but without any manifested brain cancer. OPC were isolated using magnetic-activated cell sorting (MACS) with antibodies against A2B5 antigen.