TOP TEN perturbations for 1552584_at (Homo sapiens)

Organism: Homo sapiens
Gene: 1552584_at
Selected probe(set): 1552584_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 1552584_at (1552584_at) across 6622 perturbations tested by GENEVESTIGATOR:

lung adenocarcinoma study 9 (metastase; lymph node) / lung adenocarcinoma study 9 (metastase; brain)

Relative Expression (log2-ratio):4.7245874
Number of Samples:3 / 6
Experimental lung adenocarcinoma study 9 (metastase; lymph node)
Metastatic tumor tissue obtained from the lymph node of patients with primary lung adenocarcinoma.
Control lung adenocarcinoma study 9 (metastase; brain)
Metastatic tumor tissue obtained from the brain of patients with primary lung adenocarcinoma.

cutaneous T-cell lymphoma study 1 (tumor phase) / normal skin tissue

Relative Expression (log2-ratio):3.2183409
Number of Samples:4 / 8
Experimental cutaneous T-cell lymphoma study 1 (tumor phase)
Lesional skin biopsies from patients with cutaneous T-cell lymphoma in the tumor phase (extranodal).
Control normal skin tissue
Skin biopsies from healthy individuals.

IL-17 study 2 (2d; 200ng/ml) / IFN-g study 8 (2d; 20ng/ml)

Relative Expression (log2-ratio):-3.1776009
Number of Samples:3 / 3
Experimental IL-17 study 2 (2d; 200ng/ml)
Reconstructed human epidermis model (RHE; EpiDermTM/MatTek) incubated in assay media supplemented with 200 ng/ml of interleukin 17 (IL-17) for 2 days. Full-thickness human skin model resembles in vivo epidermal architecture.
Control IFN-g study 8 (2d; 20ng/ml)
Reconstructed human epidermis model (RHE; EpiDermTM/MatTek) incubated in assay media supplemented with 20 ng/ml of interferon gamma (IFN-g) for 2 days. Full-thickness human skin model resembles in vivo epidermal architecture.

IFN-g study 8 (2d; 20ng/ml) / untreated reconstructed human epidermis tissue

Relative Expression (log2-ratio):3.0104856
Number of Samples:3 / 3
Experimental IFN-g study 8 (2d; 20ng/ml)
Reconstructed human epidermis model (RHE; EpiDermTM/MatTek) incubated in assay media supplemented with 20 ng/ml of interferon gamma (IFN-g) for 2 days. Full-thickness human skin model resembles in vivo epidermal architecture.
Control untreated reconstructed human epidermis tissue
Control untreated reconstructed human epidermis model (RHE; EpiDermTM/MatTek) incubated in assay media. Full-thickness human skin model resembles in vivo epidermal architecture.

HIV-associated neurocognitive disorder study 7 (normal) / HIV-associated neurocognitive disorder study 6 (normal)

Relative Expression (log2-ratio):-2.9912844
Number of Samples:2 / 2
Experimental HIV-associated neurocognitive disorder study 7 (normal)
Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with normal brain pathology. The patients received antiretroviral therapy (ART).
Control HIV-associated neurocognitive disorder study 6 (normal)
Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with normal brain pathology. The patients did not receive any antiretroviral therapy (ART).

colorectal cancer study 43 (metastase; brain) / colorectal cancer study 43 (metastase; lung)

Relative Expression (log2-ratio):-2.9353456
Number of Samples:2 / 5
Experimental colorectal cancer study 43 (metastase; brain)
Metastatic tumor tissue obtained from the brain of patients with primary colorectal adenocarcinoma.
Control colorectal cancer study 43 (metastase; lung)
Metastatic tumor tissue obtained from the lung of patients with primary colon adenocarcinoma.

IL-22 study 2 (2d; 200ng/ml) / IFN-g study 8 (2d; 20ng/ml)

Relative Expression (log2-ratio):-2.9069748
Number of Samples:3 / 3
Experimental IL-22 study 2 (2d; 200ng/ml)
Reconstructed human epidermis model (RHE; EpiDermTM/MatTek) incubated in assay media supplemented with 200 ng/ml of interleukin 22 (IL-22) for 2 days. Full-thickness human skin model resembles in vivo epidermal architecture.
Control IFN-g study 8 (2d; 20ng/ml)
Reconstructed human epidermis model (RHE; EpiDermTM/MatTek) incubated in assay media supplemented with 20 ng/ml of interferon gamma (IFN-g) for 2 days. Full-thickness human skin model resembles in vivo epidermal architecture.

cutaneous sarcoidosis study 1 (lesional) / normal skin tissue

Relative Expression (log2-ratio):2.8509216
Number of Samples:13 / 5
Experimental cutaneous sarcoidosis study 1 (lesional)
Lesional skin biopsies from patients with acute cutaneous sarcoidosis.
Control normal skin tissue
Skin biopsy samples from healthy control subjects.

HIV-associated neurocognitive disorder study 4 (minimal) / normal genu sample

Relative Expression (log2-ratio):2.6669674
Number of Samples:2 / 8
Experimental HIV-associated neurocognitive disorder study 4 (minimal)
Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with minimal histopathological changes including trivial microscopic abnormalities, atherosclerosis and minimal perivascular inflammation. The patients did not receive any antiretroviral therapy (ART).
Control normal genu sample
Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from healthy subjects.

kidney transplantation study 9 (late) / normal kidney transplant

Relative Expression (log2-ratio):2.638154
Number of Samples:2 / 13
Experimental kidney transplantation study 9 (late)
Human renal allograft biopsies from deceased donors obtained 24 months after transplantation.
Control normal kidney transplant
Human renal allograft biopsies from deceased donors obtained at implantation prior to revascularization.