TOP TEN perturbations for 1552661_at (Homo sapiens)

Organism: Homo sapiens
Gene: 1552661_at
Selected probe(set): 1552662_a_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 1552661_at (1552662_a_at) across 6672 perturbations tested by GENEVESTIGATOR:

glioma study 16 (LN-319) / normal astrocyte sample

Relative Expression (log2-ratio):1.7923326
Number of Samples:2 / 3
Experimental glioma study 16 (LN-319)
Human glioma cell line LN319 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37°C and 5% CO2.
Control normal astrocyte sample
Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations.

sarcoidosis study 6 (orbital adipose tissue) / normal orbital adipose tissue

Relative Expression (log2-ratio):-1.7187691
Number of Samples:7 / 22
Experimental sarcoidosis study 6 (orbital adipose tissue)
Orbital adipose tissue samples obtained from patients who suffered from sarcoidosis. Biopsies were formalin-fixed and paraffin-embedded.
Control normal orbital adipose tissue
Normal orbital adipose tissue samples. Samples were obtained from subjects with no history of orbital disease at the time of surgery such as fat typically excised and discarded as part of routine blepharoplasty or retrobulbar fat that is snared with the eye during enucleation. Biopsies were formalin-fixed and paraffin-embedded.

glioma study 27 (glioblastoma, NOS) / glioma study 27 (astrocytoma, NOS)

Relative Expression (log2-ratio):-1.555624
Number of Samples:4 / 5
Experimental glioma study 27 (glioblastoma, NOS)
Primary tumor samples from resected brain tissues of patients with glioblastoma, NOS(WHO grade IV astrocytoma).
Control glioma study 27 (astrocytoma, NOS)
Primary tumor samples from resected brain tissues of patients with astrocytoma, NOS (WHO grade II astrocytoma).

thyroid eye disease study 1 (orbital adipose tissue) / sarcoidosis study 6 (orbital adipose tissue)

Relative Expression (log2-ratio):1.4516106
Number of Samples:27 / 7
Experimental thyroid eye disease study 1 (orbital adipose tissue)
Orbital adipose tissue samples obtained from patients who suffered from thyroid eye disease (TED). Biopsies were formalin-fixed and paraffin-embedded.
Control sarcoidosis study 6 (orbital adipose tissue)
Orbital adipose tissue samples obtained from patients who suffered from sarcoidosis. Biopsies were formalin-fixed and paraffin-embedded.

granulomatosis with polyangiitis study 3 (orbital adipose tissue) / normal orbital adipose tissue

Relative Expression (log2-ratio):-1.3452864
Number of Samples:9 / 22
Experimental granulomatosis with polyangiitis study 3 (orbital adipose tissue)
Orbital adipose tissue samples obtained from patients who suffered from granulomatosis with polyangiitis (GPA). Biopsies were formalin-fixed and paraffin-embedded.
Control normal orbital adipose tissue
Normal orbital adipose tissue samples. Samples were obtained from subjects with no history of orbital disease at the time of surgery such as fat typically excised and discarded as part of routine blepharoplasty or retrobulbar fat that is snared with the eye during enucleation. Biopsies were formalin-fixed and paraffin-embedded.

atypical teratoid/rhabdoid tumor study 1 / non-tumor brain tissue

Relative Expression (log2-ratio):1.3191109
Number of Samples:20 / 9
Experimental atypical teratoid/rhabdoid tumor study 1
Primary tumor tissue sample from the brain of pediatric patients with atypical teratoid/rhabdoid tumor (AT/RT).
Control non-tumor brain tissue
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor.

glioma study 16 (BS-149) / normal astrocyte sample

Relative Expression (log2-ratio):1.2706003
Number of Samples:2 / 3
Experimental glioma study 16 (BS-149)
Human glioma cell line BS149 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37°C and 5% CO2.
Control normal astrocyte sample
Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations.

cutaneous T-cell lymphoma study 1 (tumor phase) / normal skin tissue

Relative Expression (log2-ratio):-1.2674475
Number of Samples:4 / 8
Experimental cutaneous T-cell lymphoma study 1 (tumor phase)
Lesional skin biopsies from patients with cutaneous T-cell lymphoma in the tumor phase (extranodal).
Control normal skin tissue
Skin biopsies from healthy individuals.

atypical teratoid/rhabdoid tumor study 1 / primitive neuroectodermal tumor study 1

Relative Expression (log2-ratio):1.2198105
Number of Samples:20 / 9
Experimental atypical teratoid/rhabdoid tumor study 1
Primary tumor tissue sample from the brain of pediatric patients with atypical teratoid/rhabdoid tumor (AT/RT).
Control primitive neuroectodermal tumor study 1
Primary tumor tissue sample from the supratentorial brain of pediatric patients with primitive neuroectodermal tumor.

angiopoietin-1 study 1 (sparse) / angiopoietin-1 study 1 (confl.)

Relative Expression (log2-ratio):-1.167984
Number of Samples:2 / 2
Experimental angiopoietin-1 study 1 (sparse)
Sparse human umbilical vein endothelial cells stimulated with 100 ng /ml COMP-Angiopoietin-1 for 1h after starvation overnight.
Control angiopoietin-1 study 1 (confl.)
Confluent human umbilical vein endothelial cells stimulated with 100 ng /ml COMP-Angiopoietin-1 for 1h after starvation overnight.