TOP TEN perturbations for 1552722_at (Homo sapiens)

Organism: Homo sapiens
Gene: 1552722_at
Selected probe(set): 220359_s_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 1552722_at (220359_s_at) across 6672 perturbations tested by GENEVESTIGATOR:

atypical teratoid/rhabdoid tumor study 1 / non-tumor brain tissue

Relative Expression (log2-ratio):-6.2420816
Number of Samples:20 / 9
Experimental atypical teratoid/rhabdoid tumor study 1
Primary tumor tissue sample from the brain of pediatric patients with atypical teratoid/rhabdoid tumor (AT/RT).
Control non-tumor brain tissue
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor.

HIV-associated neurocognitive disorder study 7 (normal) / HIV-associated neurocognitive disorder study 6 (normal)

Relative Expression (log2-ratio):6.179594
Number of Samples:2 / 2
Experimental HIV-associated neurocognitive disorder study 7 (normal)
Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with normal brain pathology. The patients received antiretroviral therapy (ART).
Control HIV-associated neurocognitive disorder study 6 (normal)
Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with normal brain pathology. The patients did not receive any antiretroviral therapy (ART).

medulloblastoma study 1 / non-tumor brain tissue

Relative Expression (log2-ratio):-6.1197596
Number of Samples:17 / 9
Experimental medulloblastoma study 1
Primary tumor tissue sample from the infratentorial brain of pediatric patients with classical medulloblastoma.
Control non-tumor brain tissue
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor.

brain tumor study 1 (ependymoma) / normal brain tissue

Relative Expression (log2-ratio):-5.973362
Number of Samples:46 / 12
Experimental brain tumor study 1 (ependymoma)
Primary tumor tissue sample from the brain of patients with ependymoma.
Control normal brain tissue
Histologically normal and non-neoplastic tissue sample from different brain anatomical sites of patients with primary brain tumors.

glioma study 5 / non-tumor brain tissue

Relative Expression (log2-ratio):-5.949873
Number of Samples:12 / 9
Experimental glioma study 5
Primary tumor tissue sample from the supratentorial brain of pediatric patients with glioblastoma multiformae.
Control non-tumor brain tissue
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor.

medulloblastoma study 2 / non-tumor brain tissue

Relative Expression (log2-ratio):-5.8488836
Number of Samples:4 / 9
Experimental medulloblastoma study 2
Primary tumor tissue sample from the infratentorial brain of pediatric patients with large-cell anaplastic medulloblastoma.
Control non-tumor brain tissue
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor.

primitive neuroectodermal tumor study 1 / non-tumor brain tissue

Relative Expression (log2-ratio):-5.791956
Number of Samples:9 / 9
Experimental primitive neuroectodermal tumor study 1
Primary tumor tissue sample from the supratentorial brain of pediatric patients with primitive neuroectodermal tumor.
Control non-tumor brain tissue
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor.

brain tumor study 1 (medulloblastoma) / normal brain tissue

Relative Expression (log2-ratio):-5.606267
Number of Samples:22 / 12
Experimental brain tumor study 1 (medulloblastoma)
Primary tumor tissue sample from the brain of patients with medulloblastoma.
Control normal brain tissue
Histologically normal and non-neoplastic tissue sample from different brain anatomical sites of patients with primary brain tumors.

HIV-associated neurocognitive disorder study 9 (HIVE) / HIV-associated dementia study 1

Relative Expression (log2-ratio):-5.3926334
Number of Samples:5 / 7
Experimental HIV-associated neurocognitive disorder study 9 (HIVE)
Postmortem cerebral white matter tissue from HIV-1-infected patients with substantial HIV-associated neurocognitive impairment (HAND). Patients had no encephalitis (HIVE) or other neuropathological defect.
Control HIV-associated dementia study 1
Postmortem basal ganglia tissue from HIV-1-infected patients with substantial HIV-associated neurocognitive impairment (HAND). Patients had no encephalitis (HIVE) or other neuropathological defect.

brain tumor study 1 (glioblastoma) / normal brain tissue

Relative Expression (log2-ratio):-4.9020996
Number of Samples:34 / 12
Experimental brain tumor study 1 (glioblastoma)
Primary tumor tissue sample from the brain of patients with glioblastoma multiformae.
Control normal brain tissue
Histologically normal and non-neoplastic tissue sample from different brain anatomical sites of patients with primary brain tumors.