Organism: Homo sapiens
Gene: 1553031_at
Selected probe(set): 237690_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 1553031_at (237690_at) across 6673 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):-4.9858294
Number of Samples:2 / 10

Experimental	Langerhans cell histiocytosis study 2 (multifocal)
	Langerhans cell histiocytes (LCH, CD207+) samples isolated from LCH lesions of patients with multifocal (bone, skin lesions) disease.
Control	normal epidermal Langerhans cell sample
	Normal epidermal Langerhans cells (CD207+) were isolated from skin of children donors (age < 18 years). The Langerhans cells were isolated from presumably healthy tissue.

Relative Expression (log2-ratio):-4.8962526
Number of Samples:2 / 10

Experimental	Langerhans cell histiocytosis study 2 (multisystem)
	Langerhans cell histiocytes (LCH, CD207+) samples isolated from LCH lesions of patients with multifocal, multisystem (disseminated) disease. Both patients received chemotherapy. Sites of LCH lesions: subj.ID:1 (skin, lungs, multiple skull, mastoid, gingiva), subj.ID:13 (mandible, skull, vertebrae, recurrent orbit, liver, spleen, pituitary gland).
Control	normal epidermal Langerhans cell sample
	Normal epidermal Langerhans cells (CD207+) were isolated from skin of children donors (age < 18 years). The Langerhans cells were isolated from presumably healthy tissue.

Relative Expression (log2-ratio):-4.8627415
Number of Samples:8 / 10

Experimental	Langerhans cell histiocytosis study 2 (unifocal)
	Langerhans cell histiocytes (LCH, CD207+) samples isolated from LCH lesions of patients with unifocal, single system disease (bone lesion).
Control	normal epidermal Langerhans cell sample
	Normal epidermal Langerhans cells (CD207+) were isolated from skin of children donors (age < 18 years). The Langerhans cells were isolated from presumably healthy tissue.

Relative Expression (log2-ratio):-4.8506966
Number of Samples:40 / 2

Experimental	melanoma study 34 (metastatic)
	Metastatic tumor tissue sample obtained from the patients with metastatic malignant melanoma of the skin. Metastatic samples composed of 22 macroscopic lymph node metastases, 16 subcutaneous metastases and 2 solid organ metastases (adrenal and brain).
Control	melanoma study 34 (in situ)
	Tumor tissue from the skin of patients with melanoma in situ.

Relative Expression (log2-ratio):-4.535445
Number of Samples:2 / 2

Experimental	ovarian tumor study 30 (PDX; transitional cell carcinoma, NOS; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary transitional cell carcinoma, NOS of the ovary (subcutaneously implanted).
Control	ovarian tumor study 30 (PDX; mixed tumor, malignant, NOS; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary mixed tumor, malignant, NOS of the ovary (subcutaneously implanted).

Relative Expression (log2-ratio):-4.505126
Number of Samples:3 / 3

Experimental	AsPC-1
	Human xenograft derived metastatic cancer cell line derived from mouse xenografts initiated with metastatic cells from the ascites derived from a 62 years old female Caucasian patient with pancreatic adenocarcinoma. Synonyms:AsPc-1; Aspc-1; ASPC-1; As-PC1; ASPC1; AsPC1; Aspc1; AsPc1 Cellosaurus code:
Control	BxPC-3
	Human pancreatic adenocarcinoma cell line derived from a 61 years old female patient. Synonyms:BxPc-3; BXPC-3; Bx-PC3; BXPC3; BxPC3; BxPc3 Cellosaurus code:

Relative Expression (log2-ratio):-4.3211174
Number of Samples:40 / 4

Experimental	melanoma study 34 (metastatic)
	Metastatic tumor tissue sample obtained from the patients with metastatic malignant melanoma of the skin. Metastatic samples composed of 22 macroscopic lymph node metastases, 16 subcutaneous metastases and 2 solid organ metastases (adrenal and brain).
Control	normal skin tissue
	Normal skin tissue.

Relative Expression (log2-ratio):-4.1844683
Number of Samples:13 / 2

Experimental	ovarian tumor study 30 (PDX; serous cystadenocarcinoma, NOS; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary serous cystadenocarcinoma, NOS of the ovary (subcutaneously implanted).
Control	ovarian tumor study 30 (PDX; mixed tumor, malignant, NOS; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary mixed tumor, malignant, NOS of the ovary (subcutaneously implanted).

Relative Expression (log2-ratio):-3.838296
Number of Samples:14 / 2

Experimental	melanoma study 34 (primary)
	Primary tumor tissue from the skin of patients with primary cutaneous melanoma (PCM). PCM consisted of 2 thin melanomas (< 1 mm; T1), 3 intermediate-thickness melanomas (1–4 mm; T2-3), and 9 thick melanomas (> 4 mm; T4).
Control	melanoma study 34 (in situ)
	Tumor tissue from the skin of patients with melanoma in situ.

Relative Expression (log2-ratio):-3.8299885
Number of Samples:5 / 10

Experimental	atopic dermatitis study 21 (lesional; epidermis)
	Lesional epidermal samples isolated from patient with moderate-to-severe chronic atopic dermatitis by laser capture microdissection. Patients' cohort characteristics: 3 males and 2 females; age 27-59 years (mean age: 39.4 years); SCORing of Atopic Dermatitis index (SCORAD) ranging from 45-65; total IgE: 14-1821 kU/l; eosinophilic count: 1.4-11.8 %.
Control	normal epidermis tissue
	Epidermal samples isolated from healthy subjects by laser capture microdissection.