TOP TEN perturbations for 1553264_a_at (Homo sapiens)

Organism: Homo sapiens
Gene: 1553264_a_at
Selected probe(set): 221914_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 1553264_a_at (221914_at) across 6673 perturbations tested by GENEVESTIGATOR:

HIV-associated neurocognitive disorder study 7 (normal) / HIV-associated neurocognitive disorder study 6 (normal)

Relative Expression (log2-ratio):4.7348976
Number of Samples:2 / 2
Experimental HIV-associated neurocognitive disorder study 7 (normal)
Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with normal brain pathology. The patients received antiretroviral therapy (ART).
Control HIV-associated neurocognitive disorder study 6 (normal)
Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with normal brain pathology. The patients did not receive any antiretroviral therapy (ART).

brain tumor study 1 (ependymoma) / normal brain tissue

Relative Expression (log2-ratio):-4.1277733
Number of Samples:46 / 12
Experimental brain tumor study 1 (ependymoma)
Primary tumor tissue sample from the brain of patients with ependymoma.
Control normal brain tissue
Histologically normal and non-neoplastic tissue sample from different brain anatomical sites of patients with primary brain tumors.

atypical teratoid/rhabdoid tumor study 1 / non-tumor brain tissue

Relative Expression (log2-ratio):-3.7186508
Number of Samples:20 / 9
Experimental atypical teratoid/rhabdoid tumor study 1
Primary tumor tissue sample from the brain of pediatric patients with atypical teratoid/rhabdoid tumor (AT/RT).
Control non-tumor brain tissue
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor.

brain tumor study 1 (glioblastoma) / normal brain tissue

Relative Expression (log2-ratio):-3.1160698
Number of Samples:34 / 12
Experimental brain tumor study 1 (glioblastoma)
Primary tumor tissue sample from the brain of patients with glioblastoma multiformae.
Control normal brain tissue
Histologically normal and non-neoplastic tissue sample from different brain anatomical sites of patients with primary brain tumors.

glioma study 5 / non-tumor brain tissue

Relative Expression (log2-ratio):-3.053812
Number of Samples:12 / 9
Experimental glioma study 5
Primary tumor tissue sample from the supratentorial brain of pediatric patients with glioblastoma multiformae.
Control non-tumor brain tissue
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor.

glioma study 3 / non-tumor brain tissue

Relative Expression (log2-ratio):-2.9584045
Number of Samples:81 / 23
Experimental glioma study 3
Primary tumor tissue sample from the brain of patients with glioblastoma multiformae.
Control non-tumor brain tissue
Brain tissue samples from patients with epilepsy and without any manifested brain cancer.

glioma study 12 (unspecified) / non-tumor brain tissue

Relative Expression (log2-ratio):-2.894658
Number of Samples:68 / 6
Experimental glioma study 12 (unspecified)
Primary tumor tissue sample from the brain of patients with unspecified glioma.
Control non-tumor brain tissue
Histologically normal brain tissue.

glioma study 27 (glioblastoma, NOS) / glioma study 27 (pilocytic astrocytoma)

Relative Expression (log2-ratio):-2.8874588
Number of Samples:4 / 2
Experimental glioma study 27 (glioblastoma, NOS)
Primary tumor samples from resected brain tissues of patients with glioblastoma, NOS(WHO grade IV astrocytoma).
Control glioma study 27 (pilocytic astrocytoma)
Primary tumor samples from resected brain tissues of patients with pilocytic astrocytoma (WHO grade I astrocytoma).

brain tumor study 1 (pilocytic astrocytoma) / normal brain tissue

Relative Expression (log2-ratio):-2.7150087
Number of Samples:15 / 12
Experimental brain tumor study 1 (pilocytic astrocytoma)
Primary tumor tissue sample from the brain of patients with pilocytic astrocytoma.
Control normal brain tissue
Histologically normal and non-neoplastic tissue sample from different brain anatomical sites of patients with primary brain tumors.

glioma study 27 (astrocytoma, anaplastic) / glioma study 27 (pilocytic astrocytoma)

Relative Expression (log2-ratio):-2.67593
Number of Samples:6 / 2
Experimental glioma study 27 (astrocytoma, anaplastic)
Primary tumor samples from resected brain tissues of patients with anaplastic astrocytoma(WHO grade III astrocytoma).
Control glioma study 27 (pilocytic astrocytoma)
Primary tumor samples from resected brain tissues of patients with pilocytic astrocytoma (WHO grade I astrocytoma).