TOP TEN perturbations for 1553276_at (Homo sapiens)
Organism: Homo sapiens
Gene: 1553276_at
Selected probe(set): 1553276_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 1553276_at (1553276_at) across 6537 perturbations tested by GENEVESTIGATOR:
bone cancer study 1 (PDX; chondrosarcoma, NOS; primary) / bone cancer study 1 (PDX; osteosarcoma, NOS; primary)
Relative Expression (log2-ratio):4.0274653Number of Samples:2 / 2
Experimental | bone cancer study 1 (PDX; chondrosarcoma, NOS; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary chondrosarcoma, NOS of the bone (subcutaneously implanted). | |
Control | bone cancer study 1 (PDX; osteosarcoma, NOS; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary osteosarcoma, NOS of the bone (subcutaneously implanted). |
bone cancer study 1 (PDX; chondrosarcoma, NOS; primary) / bone cancer study 1 (PDX; myxoid chondrosarcoma; primary)
Relative Expression (log2-ratio):3.988018Number of Samples:2 / 2
Experimental | bone cancer study 1 (PDX; chondrosarcoma, NOS; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary chondrosarcoma, NOS of the bone (subcutaneously implanted). | |
Control | bone cancer study 1 (PDX; myxoid chondrosarcoma; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary myxoid chondrosarcoma of the bone (subcutaneously implanted). |
bone cancer study 1 (PDX; chondrosarcoma, NOS; primary) / bone cancer study 1 (PDX; chondroblastic osteosarcoma; primary)
Relative Expression (log2-ratio):3.875184Number of Samples:2 / 2
Experimental | bone cancer study 1 (PDX; chondrosarcoma, NOS; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary chondrosarcoma, NOS of the bone (subcutaneously implanted). | |
Control | bone cancer study 1 (PDX; chondroblastic osteosarcoma; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary chondroblastic osteosarcoma of the bone (subcutaneously implanted). |
small cell lung cancer study 4 (XCL from PDX) / small cell lung cancer study 4 (XCL from CDX)
Relative Expression (log2-ratio):2.5290546Number of Samples:3 / 11
Experimental | small cell lung cancer study 4 (XCL from PDX) |
Xenograft-derived cell lines (XCL) established from a small cell lung carcinoma (SCLC) patient derived xenografts (PDX). The discarded tissue from three chemo-naive patients (LX22; LX33 and LX35) was obtained during bronchoscopy and used to generate a xenograft. Aseptically resuspended tumour cells were injected s.c. in the flanks of nonobese diabetic/severe combined immunodeficient mice. The mice were sacrificed when the P0 tumors reached 1cm in diameter. Obtained cells were used for conventional cell culture cultivation. | |
Control | small cell lung cancer study 4 (XCL from CDX) |
Xenograft-derived cell lines (XCL) established from a small cell lung carcinoma (SCLC) publicly available cell lines derived xenografts (CDX derived cell lines). Xenografts were grown in the flanks of a nude mice. Obtained cells were cultivated under conventional tissue culture conditions. |
small cell lung cancer study 4 (2. gen. PDX) / small cell lung cancer study 4 (2. gen. CDX)
Relative Expression (log2-ratio):1.7131801Number of Samples:4 / 12
Experimental | small cell lung cancer study 4 (2. gen. PDX) |
Xenografts (secondary) tumor tissue samples derived from a PDX-derived cell lines. A patient derived xenograft (PDX)-derived cell lines were grown under conventional tissue culture conditions for six months and then reimplanted to generate secondary xenografts (2. gen.). | |
Control | small cell lung cancer study 4 (2. gen. CDX) |
Xenografts (secondary) tumor tissue samples derived from a CDX-derived cell lines. A cell line derived xenograft (CDX)-derived cell lines were grown under conventional tissue culture conditions for six months and then reimplanted to generate secondary xenografts (2. gen.). |
glioma study 5 / non-tumor brain tissue
Relative Expression (log2-ratio):1.6511769Number of Samples:12 / 9
Experimental | glioma study 5 |
Primary tumor tissue sample from the supratentorial brain of pediatric patients with glioblastoma multiformae. | |
Control | non-tumor brain tissue |
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor. |
stem cell differentiation study 41 (T3pi) / undifferentiated hES-T3 cell sample
Relative Expression (log2-ratio):-1.579133Number of Samples:2 / 3
Experimental | stem cell differentiation study 41 (T3pi) |
Sample of pancreatic islet-like cell clusters differentiated from human embryonic stem cells T3 with female karyotype. | |
Control | undifferentiated hES-T3 cell sample |
Undifferentiated human embryonic stem cells T3. |
primitive neuroectodermal tumor study 1 / non-tumor brain tissue
Relative Expression (log2-ratio):1.5539117Number of Samples:9 / 9
Experimental | primitive neuroectodermal tumor study 1 |
Primary tumor tissue sample from the supratentorial brain of pediatric patients with primitive neuroectodermal tumor. | |
Control | non-tumor brain tissue |
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor. |
SKVCR2.0 / SK-OV-3
Relative Expression (log2-ratio):-1.4765706Number of Samples:2 / 2
Experimental | SKVCR2.0 |
Human metastatic cancer cell line derived from the ascites of a patent with adenocarcinoma of the ovary. Vincristine-resistant derivative of the ovarian adenocarcinoma cell line SKOV3 capable of growing in media with 2.0 µg/ml vincristine drug. Parental cell line:: SK-OV-3 Synonyms:SKVCR 2.0; SK VCR 2 Cellosaurus code: | |
Control | SK-OV-3 |
Human metastatic cancer cell line derived from the ascites of a patient with ovarian serous cystadenocarcinoma. Synonyms:SKOV-3; SK.OV.3; SKOV3; SKO3 Cellosaurus code: |
brain tumor study 1 (glioblastoma) / brain tumor study 1 (ependymoma)
Relative Expression (log2-ratio):1.3071141Number of Samples:34 / 46
Experimental | brain tumor study 1 (glioblastoma) |
Primary tumor tissue sample from the brain of patients with glioblastoma multiformae. | |
Control | brain tumor study 1 (ependymoma) |
Primary tumor tissue sample from the brain of patients with ependymoma. |