TOP TEN perturbations for 201172_x_at (Homo sapiens)

Organism: Homo sapiens
Gene: 201172_x_at
Selected probe(set): 214150_x_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 201172_x_at (214150_x_at) across 5961 perturbations tested by GENEVESTIGATOR:

F. tularensis study 1 (tularensis Schu S4) / uninfected peripheral blood monocyte sample

Relative Expression (log2-ratio):-1.9028893
Number of Samples:4 / 6
Experimental F. tularensis study 1 (tularensis Schu S4)
Peripheral blood monocytes infected with the Schu S4 isolate of Francisella tularensis (100 MOI) for 24 hours.
Control uninfected peripheral blood monocyte sample
Peripheral blood monocytes uninfected.

atypical teratoid/rhabdoid tumor study 1 / medulloblastoma study 2

Relative Expression (log2-ratio):1.6819391
Number of Samples:20 / 4
Experimental atypical teratoid/rhabdoid tumor study 1
Primary tumor tissue sample from the brain of pediatric patients with atypical teratoid/rhabdoid tumor (AT/RT).
Control medulloblastoma study 2
Primary tumor tissue sample from the infratentorial brain of pediatric patients with large-cell anaplastic medulloblastoma.

stem cell differentiation study 41 (hES-T3 EB) / undifferentiated hES-T3 cell sample

Relative Expression (log2-ratio):1.6386633
Number of Samples:2 / 3
Experimental stem cell differentiation study 41 (hES-T3 EB)
Sample of embryonic bodies (EB) differentiated from human embryonic stem cells T3 with female karyotype.
Control undifferentiated hES-T3 cell sample
Undifferentiated human embryonic stem cells T3.

Alzheimer's disease study 8 / normal pyramidal neuron (middle temporal gyrus)

Relative Expression (log2-ratio):1.5684967
Number of Samples:15 / 12
Experimental Alzheimer's disease study 8
Cortical layer III pyramidal neurons of the middle temporal gyrus of clinically and neuropathologically classified late-onset Alzheimer´s disease afflicted individuals. Subjects in this group had a Braak stage of V or VI with a CERAD score of moderate or frequent.
Control normal pyramidal neuron (middle temporal gyrus)
Cortical layer III pyramidal neurons of the middle temporal gyrus of clinically classified as neurologically normal individuals. Subjects in this group had a Braak stage ranging from I to II with a infrequent Consortium to Establish a Registry for Alzheimer's Disease (CERAD) neuritic plaque density.

T-cell isolation study 11 / T-cell isolation study 6

Relative Expression (log2-ratio):-1.5477161
Number of Samples:2 / 2
Experimental T-cell isolation study 11
CD4+ resting memory T-cell were isolated from peripheral blood buffy coat of healthy donors after storage for 24 hours at 20°C. The cell fraction was first enriched via density gradient centrifugation with LSM 1077 Ficoll and than FACS sorted as CD3+/CD4+/CD45RO+/CD45RA- population.
Control T-cell isolation study 6
CD4+ resting memory T-cell were isolated from whole peripheral blood of healthy donors with no delay. The cell fraction was first enriched via density gradient centrifugation with LSM 1077 Ficoll and than FACS sorted as CD3+/CD4+/CD45RO+/CD45RA- population.

glioma study 27 (astrocytoma, anaplastic) / glioma study 27 (pilocytic astrocytoma)

Relative Expression (log2-ratio):1.4524183
Number of Samples:6 / 2
Experimental glioma study 27 (astrocytoma, anaplastic)
Primary tumor samples from resected brain tissues of patients with anaplastic astrocytoma(WHO grade III astrocytoma).
Control glioma study 27 (pilocytic astrocytoma)
Primary tumor samples from resected brain tissues of patients with pilocytic astrocytoma (WHO grade I astrocytoma).

ovarian tumor study 11 (low grade) / normal ovarian surface epithelial cell sample

Relative Expression (log2-ratio):1.4387722
Number of Samples:11 / 6
Experimental ovarian tumor study 11 (low grade)
Human microdissected tumor cells from the ovary of patients with low grade serous carcinoma.
Control normal ovarian surface epithelial cell sample
Human microdissected ovarian surface epithelial cell sample from the ovary of healthy individuals.

brain tumor study 1 (pilocytic astrocytoma) / brain tumor study 1 (medulloblastoma)

Relative Expression (log2-ratio):1.305376
Number of Samples:15 / 22
Experimental brain tumor study 1 (pilocytic astrocytoma)
Primary tumor tissue sample from the brain of patients with pilocytic astrocytoma.
Control brain tumor study 1 (medulloblastoma)
Primary tumor tissue sample from the brain of patients with medulloblastoma.

medulloblastoma study 2 / non-tumor brain tissue

Relative Expression (log2-ratio):-1.2614975
Number of Samples:4 / 9
Experimental medulloblastoma study 2
Primary tumor tissue sample from the infratentorial brain of pediatric patients with large-cell anaplastic medulloblastoma.
Control non-tumor brain tissue
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor.

glioma study 12 (glioblastoma) / non-tumor brain tissue

Relative Expression (log2-ratio):1.2572794
Number of Samples:165 / 6
Experimental glioma study 12 (glioblastoma)
Primary tumor tissue sample from the brain of patients with glioblastoma multiformae.
Control non-tumor brain tissue
Histologically normal brain tissue.