TOP TEN perturbations for 38386_r_at (Homo sapiens)
Organism: Homo sapiens
Gene: 38386_r_at
Selected probe(set): 201415_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 38386_r_at (201415_at) across 6674 perturbations tested by GENEVESTIGATOR:
ovarian tumor study 11 (low grade) / normal ovarian surface epithelial cell sample
Relative Expression (log2-ratio):2.205719Number of Samples:11 / 6
Experimental | ovarian tumor study 11 (low grade) |
Human microdissected tumor cells from the ovary of patients with low grade serous carcinoma. | |
Control | normal ovarian surface epithelial cell sample |
Human microdissected ovarian surface epithelial cell sample from the ovary of healthy individuals. |
oncolytic herpes simplex virus study 2 / mock infected peripheral nerve sheath tumor (S462) cell sample
Relative Expression (log2-ratio):-2.171754Number of Samples:3 / 3
Experimental | oncolytic herpes simplex virus study 2 |
Human malignant peripheral nerve sheath tumor (S462) cells infected with G207, an ICP34.5-deleted oncolytic herpes simplex virus (oHSV) for 6 hours. | |
Control | mock infected peripheral nerve sheath tumor (S462) cell sample |
Human malignant peripheral nerve sheath tumor (S462) cells mock infected for 6 hours. |
glioma study 17 ( small cell glioblastoma; unsorted) / non-tumor cortical tissue
Relative Expression (log2-ratio):2.169835Number of Samples:2 / 4
Experimental | glioma study 17 ( small cell glioblastoma; unsorted) |
Brain cells isolated from high grade small cell glioblastoma (grade IV). Tumor tissue was dissociated using enzymatic treatment and all cells were used for RNA isolation. Patients were 56 ± 3 years old males. | |
Control | non-tumor cortical tissue |
Cortical tissue obtained from patients with epilepsy, but without any manifested brain cancer. The tissue was dissociated using enzymatic treatment, but all brain cell types were used for analyses. |
ovarian tumor study 11 (borderline) / normal ovarian surface epithelial cell sample
Relative Expression (log2-ratio):2.0589714Number of Samples:8 / 6
Experimental | ovarian tumor study 11 (borderline) |
Human microdissected tumor cells from the ovary of patients with low-malignant (borderline) tumors of the ovary. | |
Control | normal ovarian surface epithelial cell sample |
Human microdissected ovarian surface epithelial cell sample from the ovary of healthy individuals. |
glioma study 17 (glioblastoma; unsorted) / non-tumor cortical tissue
Relative Expression (log2-ratio):2.0478382Number of Samples:2 / 4
Experimental | glioma study 17 (glioblastoma; unsorted) |
Brain cells isolated from high grade glioblastoma (grade IV). Tumor tissue was dissociated using enzymatic treatment and all cells were used for RNA isolation. | |
Control | non-tumor cortical tissue |
Cortical tissue obtained from patients with epilepsy, but without any manifested brain cancer. The tissue was dissociated using enzymatic treatment, but all brain cell types were used for analyses. |
kidney transplantation study 16 (2 week) / normal natural killer cell (CD56+) sample
Relative Expression (log2-ratio):-2.0296593Number of Samples:3 / 3
Experimental | kidney transplantation study 16 (2 week) |
CD56+ natural killer cell samples derived from kidney transplant patients 2 weeks post-transplantation. Samples were collected 2 week after transplantation and administration of immunosuppressive therapy (day 1-4: methylprednisolone (60 mg); 3 doses: rabbit polyclonal anti-thymocyte globulin (ThymoglobulinH; 6 mg/kg); mycophenolate mofetil (CellCeptH); and tacrolimus (PrografH). | |
Control | normal natural killer cell (CD56+) sample |
CD56+ natural killer cell samples derived from healthy control subjects. |
T-cell activation study 2 / quiescent CD4+ T-cell sample
Relative Expression (log2-ratio):1.8831425Number of Samples:2 / 2
Experimental | T-cell activation study 2 |
CD4+ T-cell samples derived from PBMC´s of HIV-seronegative donors were activated with plate bound CD3 (1ug/ml) and soluble CD28 (50ng/ml) for 2 days.. | |
Control | quiescent CD4+ T-cell sample |
Quiescent CD4+ T-cell samples derived from PBMC´s of HIV-seronegative donors. |
pancreatic cancer study 3 (ipmc) / normal pancreas tissue
Relative Expression (log2-ratio):1.8646526Number of Samples:6 / 6
Experimental | pancreatic cancer study 3 (ipmc) |
Intraductal papillary mucinous carcinoma from patients with pancreatic cancer. | |
Control | normal pancreas tissue |
Normal human pancreatic tissue. |
MCF-7:2A / MCF-7
Relative Expression (log2-ratio):1.7953787Number of Samples:4 / 4
Experimental | MCF-7:2A |
Long-term estrogen deprived breast cancer cells MCF-7, which are resistant to estrogen-deprivation and therefore show an aromatase inhibitor resistantance. MCF-7 is human metastatic cancer cell line derived from the pleural effusion of a patient with adenocarcinoma of the breast. Parental cell line:: MCF-7 Cellosaurus code: | |
Control | MCF-7 |
Human metastatic cancer cell line derived from the pleural effusion of a patient (69 years old, caucasian) with adenocarcinoma of the breast. Synonyms:MCF 7; MCF.7; MCF7; Michigan Cancer Foundation 7; ssMCF7; MCF7/WT; IBMF-7; MCF7-CTRL Cellosaurus code: |
pancreatic cancer study 3 (ipmn) / normal pancreas tissue
Relative Expression (log2-ratio):1.7672138Number of Samples:3 / 6
Experimental | pancreatic cancer study 3 (ipmn) |
Intraductal papillary mucinous neoplasm from patients with pancreatic cancer. | |
Control | normal pancreas tissue |
Normal human pancreatic tissue. |