Organism: Homo sapiens
Gene: 38425_at
Selected probe(set): 202772_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 38425_at (202772_at) across 6674 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):-2.154893
Number of Samples:4 / 2

Experimental	lung cancer study 1 (PDX; pseudosarcomatous carcinoma; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary pseudosarcomatous carcinoma of the lung (subcutaneously implanted).
Control	lung cancer study 1 (PDX; non-small cell carcinoma; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary non-small cell carcinoma of the lung (subcutaneously implanted).

Relative Expression (log2-ratio):-1.8583279
Number of Samples:3 / 10

Experimental	HCC study 23 (portal vein infiltration)
	Tumor liver tissue samples derived from patients with hepatocellular carcinoma (HCC) with portal vein infiltration. Samples were derived by laser capture microdissection (LCM) from patients with HCC from the Chinese National Human Genome Center at Shanghai.
Control	adjacent liver tissue
	Normal adjacent liver tissue samples derived from patients with hepatocellular carcinoma (HCC). Samples were derived by laser capture microdissection (LCM) from patients with HCC from the Chinese National Human Genome Center at Shanghai.

Relative Expression (log2-ratio):-1.8041258
Number of Samples:3 / 3

Experimental	HIF-1a/HIF-2a depletion study 1 (hypoxia; HK2)
	Proximal tubule epithelial cell line HK-2 with shRNA-mediated stable knock-down of HIF-1a and HIF-2a (Hypoxia-inducible factor 1-alpha and Hypoxia-inducible factor 2-alpha) 24 hours after treatment with hypoxia (20% O2). HK-2 cells were cultured in DMEM/F-12 supplemented with 10% fetal calf serum (FCS), 1% ITS, hydrocortisone, and antibiotics. The cells were incubated at 37 °C.
Control	HIF-1a/HIF-2a depletion study 1 (normoxia; AB81)
	Human podocyte cells AB81 with shRNA-mediated stable knock-down of HIF-1a and HIF-2a (Hypoxia-inducible factor 1-alpha and Hypoxia-inducible factor 2-alpha) 24 hours after treatment with normoxia (20% O2). Conditionally immortalized human podocytes AB81 were cultured under permissive conditions (33 °C) in RPMI-1640 supplemented with 10% FBS, antibiotics, and 1% ITS. Differentiation was induced by thermoshift to 37 °C in 6-well plates.

Relative Expression (log2-ratio):-1.7221622
Number of Samples:7 / 3

Experimental	breast cancer study 42 (metastase; lymph node)
	Metastatic tumor tissue obtained from the lymph node of patients with primary breast adenocarcinoma.
Control	breast cancer study 42 (metastase; liver)
	Metastatic tumor tissue obtained from the liver of patients with primary breast adenocarcinoma.

Relative Expression (log2-ratio):1.7031927
Number of Samples:2 / 2

Experimental	zalypsis study 2
	OPM1 multiple myeloma cells treated in vitro with zalypsis (5 nM), a novel marine-derived compound with potent antimyeloma activity. Cells were harvested at the beginning of induction of cell death (15-20% cell death as assessed by Annexin V-FITC staining). ATC code:---
Control	untreated OPM1 cell sample
	OPM1 multiple myeloma cells untreated.

Relative Expression (log2-ratio):1.656663
Number of Samples:2 / 4

Experimental	glioma study 17 (glioblastoma; unsorted)
	Brain cells isolated from high grade glioblastoma (grade IV). Tumor tissue was dissociated using enzymatic treatment and all cells were used for RNA isolation.
Control	non-tumor cortical tissue
	Cortical tissue obtained from patients with epilepsy, but without any manifested brain cancer. The tissue was dissociated using enzymatic treatment, but all brain cell types were used for analyses.

Relative Expression (log2-ratio):-1.6189003
Number of Samples:4 / 6

Experimental	F. tularensis study 1 (tularensis Schu S4)
	Peripheral blood monocytes infected with the Schu S4 isolate of Francisella tularensis (100 MOI) for 24 hours.
Control	uninfected peripheral blood monocyte sample
	Peripheral blood monocytes uninfected.

Relative Expression (log2-ratio):-1.609827
Number of Samples:5 / 5

Experimental	hepatoblastoma study 1 (NOS)
	Liver tumor tissue samples from children with hepatoblastoma (NOS). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group.
Control	normal liver tissue
	Normal liver tissue samples.

Relative Expression (log2-ratio):-1.6077023
Number of Samples:9 / 12

Experimental	Hep-G2
	Human primary cancer cell line derived from the liver of a patient with hepatocellular carcinoma. Synonyms:HEP-G2; Hep G2; HEP G2; HepG2; HEPG2 Cellosaurus code:
Control	HepaRG
	Immortalized cancer cell line derived from female patient with hepatocellular carcinoma. Cells can be induced to differentiate into hepatocyte-like cells by exposure to DMSO. Synonyms:Hepa-RG Cellosaurus code:

Relative Expression (log2-ratio):1.5657701
Number of Samples:2 / 2

Experimental	conditioned medium study 1 (HS27a)
	CD14+ monocytes treated with HS27a conditioned medium (CM) for 48h.
Control	untreated monocyte (CD14+) sample
	Untreated CD14+ monocytes from two different donors.