TOP TEN perturbations for 38474_at (Homo sapiens)
Organism: Homo sapiens
Gene: 38474_at
Selected probe(set): 1553972_a_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 38474_at (1553972_a_at) across 6674 perturbations tested by GENEVESTIGATOR:
basal cell carcinoma study 3 / normal epidermal keratinocytes
Relative Expression (log2-ratio):-3.9859324Number of Samples:4 / 2
| Experimental | basal cell carcinoma study 3 |
| Primary tumor tissue from the eyelid of patients with basal cell carcinoma (BCC). | |
| Control | normal epidermal keratinocytes |
| Normal human epidermal keratinocytes (NHEK) (Kurabo Ind., Ltd., Osaka, Japan) cultured in HuMedia-KB2 medium at 37°C in humidified air containing 5% CO2. |
lung cancer study 1 (PDX; pseudosarcomatous carcinoma; primary) / lung cancer study 1 (PDX; non-small cell carcinoma; primary)
Relative Expression (log2-ratio):-3.815073Number of Samples:4 / 2
| Experimental | lung cancer study 1 (PDX; pseudosarcomatous carcinoma; primary) |
| Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary pseudosarcomatous carcinoma of the lung (subcutaneously implanted). | |
| Control | lung cancer study 1 (PDX; non-small cell carcinoma; primary) |
| Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary non-small cell carcinoma of the lung (subcutaneously implanted). |
expO ovary cancer study 1 (granulosa cell tumor, malignant; metastatic) / expO ovary cancer study 1 (carcinoma, NOS; metastatic)
Relative Expression (log2-ratio):-3.7077904Number of Samples:2 / 5
| Experimental | expO ovary cancer study 1 (granulosa cell tumor, malignant; metastatic) |
| Metastatic tumor tissue samples obtained from patients with primary granulosa cell tumor of the ovary. | |
| Control | expO ovary cancer study 1 (carcinoma, NOS; metastatic) |
| Metastatic tumor tissue samples obtained from patients with primary carcinoma (NOS) of the ovary. |
hepatoblastoma study 1 (crowded fetal) / normal liver tissue
Relative Expression (log2-ratio):-3.6241674Number of Samples:3 / 5
| Experimental | hepatoblastoma study 1 (crowded fetal) |
| Liver tumor tissue samples from children with hepatoblastoma (epithelial type (E-HB); crowded fetal subtype). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group. | |
| Control | normal liver tissue |
| Normal liver tissue samples. |
colorectal cancer study 43 (metastase; brain) / colorectal cancer study 43 (metastase; lung)
Relative Expression (log2-ratio):3.3779716Number of Samples:2 / 5
| Experimental | colorectal cancer study 43 (metastase; brain) |
| Metastatic tumor tissue obtained from the brain of patients with primary colorectal adenocarcinoma. | |
| Control | colorectal cancer study 43 (metastase; lung) |
| Metastatic tumor tissue obtained from the lung of patients with primary colon adenocarcinoma. |
hepatoblastoma study 1 (epithelial mixed) / normal liver tissue
Relative Expression (log2-ratio):-3.3338833Number of Samples:12 / 5
| Experimental | hepatoblastoma study 1 (epithelial mixed) |
| Liver tumor tissue samples from children with hepatoblastoma (epithelial type (E-HB); epithelial mixed subtype). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group. | |
| Control | normal liver tissue |
| Normal liver tissue samples. |
ovarian tumor study 28 (endometrioid carcinoma) / ovarian tumor study 28 (adenocarcinoma)
Relative Expression (log2-ratio):-3.3125982Number of Samples:6 / 3
| Experimental | ovarian tumor study 28 (endometrioid carcinoma) |
| Primary tumor tissue sample obtained from the ovary of female patients with endometrioid carcinoma. | |
| Control | ovarian tumor study 28 (adenocarcinoma) |
| Primary tumor tissue sample obtained from the ovary of female patients with adenocarcinoma. |
expO endometrial cancer study 1 (papillary serous cystadenocarcinoma; metastatic) / expO endometrial cancer study 1 (endometrioid carcinoma; metastatic)
Relative Expression (log2-ratio):3.229662Number of Samples:2 / 20
| Experimental | expO endometrial cancer study 1 (papillary serous cystadenocarcinoma; metastatic) |
| Metastatic tumor tissue samples obtained from patients with primary papillary serous cystadenocarcinoma of the endometrium. | |
| Control | expO endometrial cancer study 1 (endometrioid carcinoma; metastatic) |
| Metastatic tumor tissue samples obtained from patients with primary endometrioid carcinoma of the endometrium. |
expO ovary cancer study 1 (endometrioid and clear cell adenocarcinoma; primary) / expO ovary cancer study 1 (adenocarcinoma with mixed subtypes; primary)
Relative Expression (log2-ratio):-3.089655Number of Samples:2 / 4
| Experimental | expO ovary cancer study 1 (endometrioid and clear cell adenocarcinoma; primary) |
| Primary tumor tissue samples obtained from the ovary of patients with endometrioid and clear cell adenocarcinoma. | |
| Control | expO ovary cancer study 1 (adenocarcinoma with mixed subtypes; primary) |
| Primary tumor tissue samples obtained from the ovary of patients with adenocarcinoma with mixed subtypes. |
hepatoblastoma study 1 (mixed epithelial and mesenchymal) / normal liver tissue
Relative Expression (log2-ratio):-3.085144Number of Samples:4 / 5
| Experimental | hepatoblastoma study 1 (mixed epithelial and mesenchymal) |
| Liver tumor tissue samples from children with hepatoblastoma (mesenchymal type (MEM-HB); mixed epithelial and mesenchymal subtype). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group. | |
| Control | normal liver tissue |
| Normal liver tissue samples. |
Organism: Homo sapiens
Gene: 38474_at
Selected probe(set): 1553972_a_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 38474_at (1553972_a_at) across 6674 perturbations tested by GENEVESTIGATOR:
basal cell carcinoma study 3 / normal epidermal keratinocytes
Relative Expression (log2-ratio):-3.9859324Number of Samples:4 / 2
| Experimental | basal cell carcinoma study 3 |
| Primary tumor tissue from the eyelid of patients with basal cell carcinoma (BCC). | |
| Control | normal epidermal keratinocytes |
| Normal human epidermal keratinocytes (NHEK) (Kurabo Ind., Ltd., Osaka, Japan) cultured in HuMedia-KB2 medium at 37°C in humidified air containing 5% CO2. |
lung cancer study 1 (PDX; pseudosarcomatous carcinoma; primary) / lung cancer study 1 (PDX; non-small cell carcinoma; primary)
Relative Expression (log2-ratio):-3.815073Number of Samples:4 / 2
| Experimental | lung cancer study 1 (PDX; pseudosarcomatous carcinoma; primary) |
| Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary pseudosarcomatous carcinoma of the lung (subcutaneously implanted). | |
| Control | lung cancer study 1 (PDX; non-small cell carcinoma; primary) |
| Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary non-small cell carcinoma of the lung (subcutaneously implanted). |
expO ovary cancer study 1 (granulosa cell tumor, malignant; metastatic) / expO ovary cancer study 1 (carcinoma, NOS; metastatic)
Relative Expression (log2-ratio):-3.7077904Number of Samples:2 / 5
| Experimental | expO ovary cancer study 1 (granulosa cell tumor, malignant; metastatic) |
| Metastatic tumor tissue samples obtained from patients with primary granulosa cell tumor of the ovary. | |
| Control | expO ovary cancer study 1 (carcinoma, NOS; metastatic) |
| Metastatic tumor tissue samples obtained from patients with primary carcinoma (NOS) of the ovary. |
hepatoblastoma study 1 (crowded fetal) / normal liver tissue
Relative Expression (log2-ratio):-3.6241674Number of Samples:3 / 5
| Experimental | hepatoblastoma study 1 (crowded fetal) |
| Liver tumor tissue samples from children with hepatoblastoma (epithelial type (E-HB); crowded fetal subtype). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group. | |
| Control | normal liver tissue |
| Normal liver tissue samples. |
colorectal cancer study 43 (metastase; brain) / colorectal cancer study 43 (metastase; lung)
Relative Expression (log2-ratio):3.3779716Number of Samples:2 / 5
| Experimental | colorectal cancer study 43 (metastase; brain) |
| Metastatic tumor tissue obtained from the brain of patients with primary colorectal adenocarcinoma. | |
| Control | colorectal cancer study 43 (metastase; lung) |
| Metastatic tumor tissue obtained from the lung of patients with primary colon adenocarcinoma. |
hepatoblastoma study 1 (epithelial mixed) / normal liver tissue
Relative Expression (log2-ratio):-3.3338833Number of Samples:12 / 5
| Experimental | hepatoblastoma study 1 (epithelial mixed) |
| Liver tumor tissue samples from children with hepatoblastoma (epithelial type (E-HB); epithelial mixed subtype). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group. | |
| Control | normal liver tissue |
| Normal liver tissue samples. |
ovarian tumor study 28 (endometrioid carcinoma) / ovarian tumor study 28 (adenocarcinoma)
Relative Expression (log2-ratio):-3.3125982Number of Samples:6 / 3
| Experimental | ovarian tumor study 28 (endometrioid carcinoma) |
| Primary tumor tissue sample obtained from the ovary of female patients with endometrioid carcinoma. | |
| Control | ovarian tumor study 28 (adenocarcinoma) |
| Primary tumor tissue sample obtained from the ovary of female patients with adenocarcinoma. |
expO endometrial cancer study 1 (papillary serous cystadenocarcinoma; metastatic) / expO endometrial cancer study 1 (endometrioid carcinoma; metastatic)
Relative Expression (log2-ratio):3.229662Number of Samples:2 / 20
| Experimental | expO endometrial cancer study 1 (papillary serous cystadenocarcinoma; metastatic) |
| Metastatic tumor tissue samples obtained from patients with primary papillary serous cystadenocarcinoma of the endometrium. | |
| Control | expO endometrial cancer study 1 (endometrioid carcinoma; metastatic) |
| Metastatic tumor tissue samples obtained from patients with primary endometrioid carcinoma of the endometrium. |
expO ovary cancer study 1 (endometrioid and clear cell adenocarcinoma; primary) / expO ovary cancer study 1 (adenocarcinoma with mixed subtypes; primary)
Relative Expression (log2-ratio):-3.089655Number of Samples:2 / 4
| Experimental | expO ovary cancer study 1 (endometrioid and clear cell adenocarcinoma; primary) |
| Primary tumor tissue samples obtained from the ovary of patients with endometrioid and clear cell adenocarcinoma. | |
| Control | expO ovary cancer study 1 (adenocarcinoma with mixed subtypes; primary) |
| Primary tumor tissue samples obtained from the ovary of patients with adenocarcinoma with mixed subtypes. |
hepatoblastoma study 1 (mixed epithelial and mesenchymal) / normal liver tissue
Relative Expression (log2-ratio):-3.085144Number of Samples:4 / 5
| Experimental | hepatoblastoma study 1 (mixed epithelial and mesenchymal) |
| Liver tumor tissue samples from children with hepatoblastoma (mesenchymal type (MEM-HB); mixed epithelial and mesenchymal subtype). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group. | |
| Control | normal liver tissue |
| Normal liver tissue samples. |