Organism: Homo sapiens
Gene: 38528_at
Selected probe(set): 212186_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 38528_at (212186_at) across 6674 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):-3.19703
Number of Samples:2 / 2

Experimental	zalypsis study 2
	OPM1 multiple myeloma cells treated in vitro with zalypsis (5 nM), a novel marine-derived compound with potent antimyeloma activity. Cells were harvested at the beginning of induction of cell death (15-20% cell death as assessed by Annexin V-FITC staining). ATC code:---
Control	untreated OPM1 cell sample
	OPM1 multiple myeloma cells untreated.

Relative Expression (log2-ratio):-2.490922
Number of Samples:2 / 2

Experimental	zalypsis study 1
	MM1S multiple myeloma cells treated in vitro with zalypsis (5 nM), a novel marine-derived compound with potent antimyeloma activity. Cells were harvested at the beginning of induction of cell death (15-20% cell death as assessed by Annexin V-FITC staining). ATC code:---
Control	untreated MM1S cell sample
	MM1S multiple myeloma cells untreated.

Relative Expression (log2-ratio):-2.1968603
Number of Samples:3 / 3

Experimental	oncolytic herpes simplex virus study 2
	Human malignant peripheral nerve sheath tumor (S462) cells infected with G207, an ICP34.5-deleted oncolytic herpes simplex virus (oHSV) for 6 hours.
Control	mock infected peripheral nerve sheath tumor (S462) cell sample
	Human malignant peripheral nerve sheath tumor (S462) cells mock infected for 6 hours.

Relative Expression (log2-ratio):2.1312847
Number of Samples:2 / 10

Experimental	HCC study 9 (HBV; HCV)
	Liver tissue biopsy sample from patients with Hepatitis B and C infection related hepatocellular carcinoma (HCC) after resection.
Control	normal liver tissue
	Normal, non-tumor liver tissue.

Relative Expression (log2-ratio):-2.1063576
Number of Samples:3 / 6

Experimental	lung adenocarcinoma study 9 (metastase; lymph node)
	Metastatic tumor tissue obtained from the lymph node of patients with primary lung adenocarcinoma.
Control	lung adenocarcinoma study 9 (metastase; brain)
	Metastatic tumor tissue obtained from the brain of patients with primary lung adenocarcinoma.

Relative Expression (log2-ratio):-2.066
Number of Samples:3 / 6

Experimental	influenza virus study 4 (A/H1N1)
	Human carcinoma cell line A549 infected with influenza A virus subtype A/WSN/33 (H1N1). Samples were taken 10 hours post-infection.
Control	mock infected A549 cell sample
	Human A549 carcinoma cells mock infected (A/H1N1). Sample was taken at 0 hours post-infection.

Relative Expression (log2-ratio):2.0250416
Number of Samples:4 / 5

Experimental	hepatoblastoma study 1 (fetal)
	Liver tumor tissue samples from children with hepatoblastoma (epithelial type (E-HB); fetal subtype). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group.
Control	normal liver tissue
	Normal liver tissue samples.

Relative Expression (log2-ratio):1.9334173
Number of Samples:3 / 2

Experimental	prostate cancer study 8 (p. canc)
	CD26+ FACS sorted prostate neoplasm cell (p. canc) samples from patients with primary prostate cancer collected after radical prostatectomy.
Control	prostate cancer study 8 (ptasc)
	CD90+ FACS sorted prostate tumor-associated stromal cell (ptasc) samples from patients with primary prostate cancer collected after radical prostatectomy.

Relative Expression (log2-ratio):1.9061346
Number of Samples:3 / 6

Experimental	stem cell differentiation study 47 (BMP-2; IBMX; 7d)
	Bone marrow-derived mesenchymal stem cell line (MSC) differentiated for 7 days in the presence of bone morphogenetic protein 2 (BMP-2, 50ng/ml) and 3-isobutyl-1-methylxanthine (IBMX, 250 μM). Cells were propagated for not more than five passages in mesenchymal stem cell growth medium, at 37 °C and in a humidified atmosphere containing 7.5 % CO2. MSCs were incubated for 24 hours in proliferation medium (PM, high glucose DMEM, 10 % FBS, 100 U/ml penicillin, and 100 μg/ml streptomycin). Subsequently PMCs were differentiated for 7 days in differentiation medium (consisting of PM with 10EXP(-6)M dexamethasone, 10 μg/ml insulin, 10EXP(-7) M rosiglitazone, 50 ng/ml BMP-2, 250 μM IBMX), and harvested. Samples are biological replicates. Normal bone marrow was obtained from 3 healthy donors (5F0138, 6F4085, 7F3458).
Control	stem cell differentiation study 47 (0d)
	Undifferentiated bone marrow-derived mesenchymal stem cell line (MSC) without any treatment. Cells were propagated for not more than five passages in mesenchymal stem cell growth medium, at 37 °C and in a humidified atmosphere containing 7.5 % CO2. MSCs were incubated for 24 hours in proliferation medium (high glucose DMEM, 10 % FBS, 100 U/ml penicillin, and 100 μg/ml streptomycin) and harvested. Samples are biological replicates. Normal bone marrow was obtained from 3 healthy donors (5F0138, 6F4085, 7F3458).

Relative Expression (log2-ratio):-1.8586264
Number of Samples:3 / 8

Experimental	cyclophosphamide study 6 (8155 uM; hES-Heps)
	hES-Heps cells exposed to 8155 uM cyclophosphamide (dissolved in 0.5% v/v DMSO) for 72 hours. Chemical was added at day 22 of differentiation. Cells were treated with the IC10 determined by a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide test (number of replicates, n = 3). ATC code:
Control	vehicle (DMSO) treated hES-Heps cell sample
	hES-Heps cells treated with vehicle (DMSO 0.5% v/v) for 72 hours. Vehicle was added at day 22 of differentiation.