TOP TEN perturbations for 38543_at (Homo sapiens)
Organism: Homo sapiens
Gene: 38543_at
Selected probe(set): 208212_s_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 38543_at (208212_s_at) across 6674 perturbations tested by GENEVESTIGATOR:
lung adenocarcinoma study 5 (EML4-ALK) / adjacent lung tissue
Relative Expression (log2-ratio):5.042506Number of Samples:3 / 20
Experimental | lung adenocarcinoma study 5 (EML4-ALK) |
Primary tumor sample from patients with stage I adenocarcinoma carrying the EML4-ALK-fusion. | |
Control | adjacent lung tissue |
Adjacent and histologically normal, non-tumorous lung tissue samples from patients with lung adenocarcinoma. |
lung adenocarcinoma study 6 (EGFR mut) / lung adenocarcinoma study 6 (EML4-ALK)
Relative Expression (log2-ratio):-4.9959774Number of Samples:24 / 8
Experimental | lung adenocarcinoma study 6 (EGFR mut) |
Primary tumor sample from patients with stage II adenocarcinoma carrying an EGFR mutation. | |
Control | lung adenocarcinoma study 6 (EML4-ALK) |
Primary tumor sample from patients with stage II adenocarcinoma carrying the EML4-ALK-fusion. |
lung adenocarcinoma study 5 (EGFR mut) / lung adenocarcinoma study 5 (EML4-ALK)
Relative Expression (log2-ratio):-4.991205Number of Samples:103 / 3
Experimental | lung adenocarcinoma study 5 (EGFR mut) |
Primary tumor sample from patients with stage I adenocarcinoma carrying an EGFR mutation. | |
Control | lung adenocarcinoma study 5 (EML4-ALK) |
Primary tumor sample from patients with stage I adenocarcinoma carrying the EML4-ALK-fusion. |
lung adenocarcinoma study 6 (EML4-ALK) / adjacent lung tissue
Relative Expression (log2-ratio):4.9298353Number of Samples:8 / 20
Experimental | lung adenocarcinoma study 6 (EML4-ALK) |
Primary tumor sample from patients with stage II adenocarcinoma carrying the EML4-ALK-fusion. | |
Control | adjacent lung tissue |
Adjacent and histologically normal, non-tumorous lung tissue samples from patients with lung adenocarcinoma. |
lung adenocarcinoma study 6 (EML4-ALK) / lung adenocarcinoma study 6 (EGFR/K-RAS/ALK -)
Relative Expression (log2-ratio):4.9138927Number of Samples:8 / 20
Experimental | lung adenocarcinoma study 6 (EML4-ALK) |
Primary tumor sample from patients with stage II adenocarcinoma carrying the EML4-ALK-fusion. | |
Control | lung adenocarcinoma study 6 (EGFR/K-RAS/ALK -) |
Primary tumor sample from patients with triple-negative stage II adenocarcinoma of the lung. The patients were not carrying any mutation in the EGFR, K- RAS or ALK gene. |
lung adenocarcinoma study 5 (EML4-ALK) / lung adenocarcinoma study 5 (EGFR/K-RAS/ALK -)
Relative Expression (log2-ratio):4.9070683Number of Samples:3 / 48
Experimental | lung adenocarcinoma study 5 (EML4-ALK) |
Primary tumor sample from patients with stage I adenocarcinoma carrying the EML4-ALK-fusion. | |
Control | lung adenocarcinoma study 5 (EGFR/K-RAS/ALK -) |
Primary tumor sample from patients with triple-negative stage I adenocarcinoma of the lung. The patients were not carrying any mutation in the EGFR, K- RAS or ALK gene. |
lung adenocarcinoma study 5 (K-RAS mut) / lung adenocarcinoma study 5 (EML4-ALK)
Relative Expression (log2-ratio):-4.8807516Number of Samples:14 / 3
Experimental | lung adenocarcinoma study 5 (K-RAS mut) |
Primary tumor sample from patients with stage I adenocarcinoma carrying a K-RAS mutation. | |
Control | lung adenocarcinoma study 5 (EML4-ALK) |
Primary tumor sample from patients with stage I adenocarcinoma carrying the EML4-ALK-fusion. |
basal cell carcinoma study 2 / normal skin tissue
Relative Expression (log2-ratio):4.8320255Number of Samples:2 / 64
Experimental | basal cell carcinoma study 2 |
Primary tumor tissue from the skin of patients with basal cell carcinoma (BCC). | |
Control | normal skin tissue |
Normal skin samples from healthy donors. |
lung adenocarcinoma study 6 (K-RAS mut) / lung adenocarcinoma study 6 (EML4-ALK)
Relative Expression (log2-ratio):-4.4821672Number of Samples:6 / 8
Experimental | lung adenocarcinoma study 6 (K-RAS mut) |
Primary tumor sample from patients with stage II adenocarcinoma carrying a K-RAS mutation. | |
Control | lung adenocarcinoma study 6 (EML4-ALK) |
Primary tumor sample from patients with stage II adenocarcinoma carrying the EML4-ALK-fusion. |
E. coli study 2 / unstimulated, normal monocyte-derived macrophage sample
Relative Expression (log2-ratio):-3.6711426Number of Samples:5 / 7
Experimental | E. coli study 2 |
Monocyte-derived macrophage samples derived from healthy control subjects cultured for 4 hours with 2.5 × 105 heat-killed E. coli. | |
Control | unstimulated, normal monocyte-derived macrophage sample |
Monocyte-derived macrophage samples derived from healthy control subjects cultured for 4 hours unstimulated. |