Organism: Homo sapiens
Gene: 38571_at
Selected probe(set): 214124_x_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 38571_at (214124_x_at) across 6674 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):3.9468927
Number of Samples:2 / 3

Experimental	brefeldin A study 1 (0.5ug/ml; p53HCT116)
	Derived human colon carcinoma cell line p53HCT116 with knockout gene for p53 was treated with 0.5 ug/ml brefeldin-A for 24 hours in McCOYs 5A medium supplemented with 10% heat inactivated FBS. ATC code:---
Control	untreated p53HCT116 cell sample
	Derived human colon carcinoma cell line p53HCT116 with knockout gene for p53 was grown in McCOYs 5A medium supplemented with 10% heat inactivated FBS.

Relative Expression (log2-ratio):3.026866
Number of Samples:3 / 3

Experimental	brefeldin A study 1 (0.5ug/ml; HCT 116)
	Human colon carcinoma cell line HCT116 was treated with 0.5 ug/ml brefeldin-A for 24 hours in McCOYs 5A medium supplemented with 10% heat inactivated FBS. ATC code:---
Control	untreated HCT 116 cell sample
	Human colon carcinoma cell line HCT116 was grown in McCOYs 5A medium supplemented with 10% heat inactivated FBS.

Relative Expression (log2-ratio):-2.9988203
Number of Samples:2 / 2

Experimental	omeprazole study 6 (600uM)
	Hepatocytes treated with compound: omeprazole (600uM; CHEMBL1503) for 24 hours. ATC code:
Control	vehicle (DMSO) treated hepatocyte sample
	Hepatocytes treated with vehicle (DMSO) for 24 hours.

Relative Expression (log2-ratio):2.7337952
Number of Samples:3 / 3

Experimental	influenza virus study 11 (A/H5N3)
	Human carcinoma cell line A549 infected with influenza A virus subtype influenza virus A/duck/Malaysia/F119/3/1997(H5N3). Samples were taken 10 hours post-infection.
Control	influenza virus study 4 (A/H1N1)
	Human carcinoma cell line A549 infected with influenza A virus subtype A/WSN/33 (H1N1). Samples were taken 10 hours post-infection.

Relative Expression (log2-ratio):2.3231697
Number of Samples:3 / 3

Experimental	influenza virus study 10 (A/H5N2)
	Human carcinoma cell line A549 infected with influenza A virus subtype influenza virus A/duck/Malaysia/F189/07/2004(H5N2). Samples were taken 10 hours post-infection.
Control	influenza virus study 4 (A/H1N1)
	Human carcinoma cell line A549 infected with influenza A virus subtype A/WSN/33 (H1N1). Samples were taken 10 hours post-infection.

Relative Expression (log2-ratio):2.2478724
Number of Samples:3 / 3

Experimental	tunicamycin study 2 (2ug/ml; p53HCT116)
	Derived human colon carcinoma cell line p53HCT116 with knockout gene for p53 was treated with 2 ug/ml tunicamycin for 24 hours in McCOYs 5A medium supplemented with 10% heat inactivated FBS. ATC code:---
Control	untreated p53HCT116 cell sample
	Derived human colon carcinoma cell line p53HCT116 with knockout gene for p53 was grown in McCOYs 5A medium supplemented with 10% heat inactivated FBS.

Relative Expression (log2-ratio):-2.1871433
Number of Samples:2 / 2

Experimental	sulindac study 5 (3000uM)
	Hepatocytes treated with compound: sulindac (3000uM; CHEMBL15770) for 24 hours. ATC code:
Control	vehicle (medium) treated hepatocyte sample
	Hepatocytes treated with vehicle (medium) for 24 hours.

Relative Expression (log2-ratio):-2.0665445
Number of Samples:4 / 18

Experimental	pediatric septic shock study 3 (toddler; subclass A)
	Whole blood samples obtained from toddlers (2 – 5 years) with septic shock subclass A. The samples were obtained within 24 hours of admission to the pediatric intensive care unit. One child did not survive. The subclass A was defined based on an empiric, discovery oriented expression filter and unsupervised hierarchical clustering. Patients in subclass A (when all age groups were pooled) had a significantly higher illness severity level (PRISM III score = 20.5, intra-quartile range (IQR) 12.5 – 32.5), a greater degree of organ failure – maximum number of organ failures 3 (IQR 3 - 4), and a higher mortality rate, a significantly higher incidence of documented Gram-positive bacterial infection and were significantly younger compared with other subclasses.
Control	normal blood sample (toddler)
	Whole blood samples from toddlers (2 – 5 years). Children who had a recent febrile illness (within 2 weeks), who recently used anti-inflammatory medications (within 2 weeks) or who had any history of chronic or acute disease associated with inflammation were excluded from the study.

Relative Expression (log2-ratio):-2.0644512
Number of Samples:2 / 2

Experimental	phenobarbital study 3 (10000uM)
	Hepatocytes treated with compound: phenobarbital (10000uM; CHEMBL40) for 24 hours. ATC code:
Control	vehicle (medium) treated hepatocyte sample
	Hepatocytes treated with vehicle (medium) for 24 hours.

Relative Expression (log2-ratio):-2.062868
Number of Samples:2 / 2

Experimental	benzbromarone study 6 (100uM)
	Hepatocytes treated with compound: benzbromarone (100uM; CHEMBL388590) for 24 hours. ATC code:
Control	vehicle (DMSO) treated hepatocyte sample
	Hepatocytes treated with vehicle (DMSO) for 24 hours.