TOP TEN perturbations for 38587_at (Homo sapiens)
Organism: Homo sapiens
Gene: 38587_at
Selected probe(set): 207475_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 38587_at (207475_at) across 6674 perturbations tested by GENEVESTIGATOR:
colorectal cancer study 33 (carcinoma; colonic mucosa) / normal colon mucosa sample
Relative Expression (log2-ratio):-2.0594864Number of Samples:5 / 5
Experimental | colorectal cancer study 33 (carcinoma; colonic mucosa) |
Colonic mucosa samples obtained by laser capture microdissection (LCM) from patients with colorectal carcinoma. | |
Control | normal colon mucosa sample |
Histopathological normal colon mucosa sample obtained by laser capture microdissection (LCM) from the distant normal colon of patients with colorectal cancer. |
colorectal adenoma study 7 (colonic mucosa) / normal colon mucosa sample
Relative Expression (log2-ratio):-1.8290682Number of Samples:5 / 5
Experimental | colorectal adenoma study 7 (colonic mucosa) |
Colonic mucosa samples obtained by laser capture microdissection (LCM) from patients with colorectal adenoma. | |
Control | normal colon mucosa sample |
Histopathological normal colon mucosa sample obtained by laser capture microdissection (LCM) from the distant normal colon of patients with colorectal cancer. |
Crohn's disease study 3 (baseline; non-responder; ileum) / normal ileum mucosa tissue
Relative Expression (log2-ratio):-1.7064133Number of Samples:10 / 6
Experimental | Crohn's disease study 3 (baseline; non-responder; ileum) |
Ileal mucosal biopsies derived from Crohn's disease patients who are non-responders to infliximab treatment. Biopsies were taken within a week prior to the first intravenous infusion of infliximab; the response to infliximab was assessed 4 to 6 weeks after the first infliximab treatment. The response was defined as a complete mucosal healing with a decrease of at least 3 points on the histological score for Crohn's disease (CDc) and as a decrease to a Mayo endoscopic subscore of 0 or 1 with a decrease to grade 0 or 1 on the histological score for ulcerative colitis (UC). More strict response criteria were used for Crohn's ileitis (CDi). More baseline information about the patients are available in the publication. | |
Control | normal ileum mucosa tissue |
Ileal mucosal biopsy from control subject obtained at the endoscopy for polyps screening. |
colorectal cancer study 33 (carcinoma; colonic crypt) / normal colonic crypt epithelial cell sample
Relative Expression (log2-ratio):-1.5692339Number of Samples:5 / 5
Experimental | colorectal cancer study 33 (carcinoma; colonic crypt) |
Colonic crypt epithelial cell samples obtained by laser capture microdissection (LCM) from patients with colorectal carcinoma. | |
Control | normal colonic crypt epithelial cell sample |
Histopathological normal colonic crypt epithelial cells obtained by laser capture microdissection (LCM) from the distant normal colon of patients with colorectal cancer. |
colorectal cancer study 33 (carcinoma; colonic mucosa) / adjacent colon mucosa sample
Relative Expression (log2-ratio):-1.4286814Number of Samples:5 / 5
Experimental | colorectal cancer study 33 (carcinoma; colonic mucosa) |
Colonic mucosa samples obtained by laser capture microdissection (LCM) from patients with colorectal carcinoma. | |
Control | adjacent colon mucosa sample |
Adjacent colon mucosa sample obtained by laser capture microdissection (LCM) from patients with colorectal cancer. |
colorectal adenoma study 7 (colonic crypt) / normal colonic crypt epithelial cell sample
Relative Expression (log2-ratio):-1.419014Number of Samples:5 / 5
Experimental | colorectal adenoma study 7 (colonic crypt) |
Colonic crypt epithelial cell samples obtained by laser capture microdissection (LCM) from patients with colorectal adenoma. | |
Control | normal colonic crypt epithelial cell sample |
Histopathological normal colonic crypt epithelial cells obtained by laser capture microdissection (LCM) from the distant normal colon of patients with colorectal cancer. |
colorectal cancer study 33 (carcinoma; colonic crypt) / adjacent colonic crypt epithelial cell sample
Relative Expression (log2-ratio):-1.236124Number of Samples:5 / 5
Experimental | colorectal cancer study 33 (carcinoma; colonic crypt) |
Colonic crypt epithelial cell samples obtained by laser capture microdissection (LCM) from patients with colorectal carcinoma. | |
Control | adjacent colonic crypt epithelial cell sample |
Adjacent colonic crypt epithelial cells obtained by laser capture microdissection (LCM) from patients with colorectal cancer. |
Crohn's disease study 10 / normal colon tissue
Relative Expression (log2-ratio):-1.2113819Number of Samples:4 / 3
Experimental | Crohn's disease study 10 |
Colon biopsies derived from patients with Crohn's disease. | |
Control | normal colon tissue |
Colon biopsies derived from healthy controls. |
colorectal cancer study 33 (carcinoma; cecum) / normal cecum tissue
Relative Expression (log2-ratio):-1.2023926Number of Samples:4 / 2
Experimental | colorectal cancer study 33 (carcinoma; cecum) |
Primary tumor samples derived from the cecum of patients with carcinoma. | |
Control | normal cecum tissue |
Normal cecal tissue samples. |
colorectal adenoma study 7 (colonic mucosa) / adjacent colon mucosa sample
Relative Expression (log2-ratio):-1.1982632Number of Samples:5 / 5
Experimental | colorectal adenoma study 7 (colonic mucosa) |
Colonic mucosa samples obtained by laser capture microdissection (LCM) from patients with colorectal adenoma. | |
Control | adjacent colon mucosa sample |
Adjacent colon mucosa sample obtained by laser capture microdissection (LCM) from patients with colorectal cancer. |