TOP TEN perturbations for 38592_s_at (Homo sapiens)
Organism: Homo sapiens
Gene: 38592_s_at
Selected probe(set): 213242_x_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 38592_s_at (213242_x_at) across 6674 perturbations tested by GENEVESTIGATOR:
doxorubicin study 3 / untreated MCF-7 cell sample
Relative Expression (log2-ratio):1.7549095Number of Samples:2 / 2
Experimental | doxorubicin study 3 |
MCF7 cells treated with 2uM doxorubicin for 24 hours. ATC code: | |
Control | untreated MCF-7 cell sample |
MCF-7 cells untreated. |
colorectal adenoma study 2 / normal colon tissue
Relative Expression (log2-ratio):-1.704957Number of Samples:5 / 6
Experimental | colorectal adenoma study 2 |
Laser microdissected human adenoma sample. | |
Control | normal colon tissue |
Laser microdissected human colonic epithelial cells sample. |
brain tumor study 1 (pilocytic astrocytoma) / normal brain tissue
Relative Expression (log2-ratio):-1.4809265Number of Samples:15 / 12
Experimental | brain tumor study 1 (pilocytic astrocytoma) |
Primary tumor tissue sample from the brain of patients with pilocytic astrocytoma. | |
Control | normal brain tissue |
Histologically normal and non-neoplastic tissue sample from different brain anatomical sites of patients with primary brain tumors. |
brain tumor study 1 (glioblastoma) / normal brain tissue
Relative Expression (log2-ratio):-1.4656324Number of Samples:34 / 12
Experimental | brain tumor study 1 (glioblastoma) |
Primary tumor tissue sample from the brain of patients with glioblastoma multiformae. | |
Control | normal brain tissue |
Histologically normal and non-neoplastic tissue sample from different brain anatomical sites of patients with primary brain tumors. |
glioma study 5 / non-tumor brain tissue
Relative Expression (log2-ratio):-1.4222355Number of Samples:12 / 9
Experimental | glioma study 5 |
Primary tumor tissue sample from the supratentorial brain of pediatric patients with glioblastoma multiformae. | |
Control | non-tumor brain tissue |
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor. |
atypical teratoid/rhabdoid tumor study 1 / non-tumor brain tissue
Relative Expression (log2-ratio):-1.3390017Number of Samples:20 / 9
Experimental | atypical teratoid/rhabdoid tumor study 1 |
Primary tumor tissue sample from the brain of pediatric patients with atypical teratoid/rhabdoid tumor (AT/RT). | |
Control | non-tumor brain tissue |
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor. |
HIV-associated neurocognitive disorder study 7 (normal) / HIV-associated neurocognitive disorder study 6 (normal)
Relative Expression (log2-ratio):1.3358955Number of Samples:2 / 2
Experimental | HIV-associated neurocognitive disorder study 7 (normal) |
Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with normal brain pathology. The patients received antiretroviral therapy (ART). | |
Control | HIV-associated neurocognitive disorder study 6 (normal) |
Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with normal brain pathology. The patients did not receive any antiretroviral therapy (ART). |
brain tumor study 1 (ependymoma) / normal brain tissue
Relative Expression (log2-ratio):-1.3248863Number of Samples:46 / 12
Experimental | brain tumor study 1 (ependymoma) |
Primary tumor tissue sample from the brain of patients with ependymoma. | |
Control | normal brain tissue |
Histologically normal and non-neoplastic tissue sample from different brain anatomical sites of patients with primary brain tumors. |
colorectal cancer study 25 / adjacent colon tissue
Relative Expression (log2-ratio):-1.29393Number of Samples:94 / 17
Experimental | colorectal cancer study 25 |
Human primary colorectal carcinoma sample. | |
Control | adjacent colon tissue |
Normal colon tissue samples adjacent to tumor from patients with colorectal cancer. |
small cell lung cancer study 4 (XCL from PDX) / small cell lung cancer study 4 (XCL from CDX)
Relative Expression (log2-ratio):-1.2529106Number of Samples:3 / 11
Experimental | small cell lung cancer study 4 (XCL from PDX) |
Xenograft-derived cell lines (XCL) established from a small cell lung carcinoma (SCLC) patient derived xenografts (PDX). The discarded tissue from three chemo-naive patients (LX22; LX33 and LX35) was obtained during bronchoscopy and used to generate a xenograft. Aseptically resuspended tumour cells were injected s.c. in the flanks of nonobese diabetic/severe combined immunodeficient mice. The mice were sacrificed when the P0 tumors reached 1cm in diameter. Obtained cells were used for conventional cell culture cultivation. | |
Control | small cell lung cancer study 4 (XCL from CDX) |
Xenograft-derived cell lines (XCL) established from a small cell lung carcinoma (SCLC) publicly available cell lines derived xenografts (CDX derived cell lines). Xenografts were grown in the flanks of a nude mice. Obtained cells were cultivated under conventional tissue culture conditions. |