TOP TEN perturbations for 38608_at (Homo sapiens)
Organism: Homo sapiens
Gene: 38608_at
Selected probe(set): 206400_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 38608_at (206400_at) across 6674 perturbations tested by GENEVESTIGATOR:
melanoma study 34 (metastatic) / melanoma study 34 (in situ)
Relative Expression (log2-ratio):-7.35742Number of Samples:40 / 2
| Experimental | melanoma study 34 (metastatic) |
| Metastatic tumor tissue sample obtained from the patients with metastatic malignant melanoma of the skin. Metastatic samples composed of 22 macroscopic lymph node metastases, 16 subcutaneous metastases and 2 solid organ metastases (adrenal and brain). | |
| Control | melanoma study 34 (in situ) |
| Tumor tissue from the skin of patients with melanoma in situ. |
melanoma study 34 (metastatic) / normal skin tissue
Relative Expression (log2-ratio):-7.3206863Number of Samples:40 / 4
| Experimental | melanoma study 34 (metastatic) |
| Metastatic tumor tissue sample obtained from the patients with metastatic malignant melanoma of the skin. Metastatic samples composed of 22 macroscopic lymph node metastases, 16 subcutaneous metastases and 2 solid organ metastases (adrenal and brain). | |
| Control | normal skin tissue |
| Normal skin tissue. |
expO cervical cancer study 1 (squamous cell carcinoma, keratinizing type, NOS; primary) / expO cervical cancer study 1 (adenosquamous carcinoma; primary)
Relative Expression (log2-ratio):6.5827513Number of Samples:3 / 2
| Experimental | expO cervical cancer study 1 (squamous cell carcinoma, keratinizing type, NOS; primary) |
| Primary tumor tissue samples obtained from the cervix uteri of patients with squamous cell carcinoma, keratinizing type (NOS). | |
| Control | expO cervical cancer study 1 (adenosquamous carcinoma; primary) |
| Primary tumor tissue samples obtained from the cervix uteri of patients with adenosquamous carcinoma. |
expO skin cancer study 1 (squamous cell carcinoma, NOS; metastatic) / expO skin cancer study 1 (malignant melanoma, NOS; metastatic)
Relative Expression (log2-ratio):5.726631Number of Samples:2 / 9
| Experimental | expO skin cancer study 1 (squamous cell carcinoma, NOS; metastatic) |
| Metastatic tumor tissue samples obtained from patients with primary squamous cell carcinoma (NOS) of the skin. | |
| Control | expO skin cancer study 1 (malignant melanoma, NOS; metastatic) |
| Metastatic tumor tissue samples obtained from patients with primary malignant melanoma (NOS) of the skin. |
esophageal adenocarcinoma study 1 / normal esophageal epithelium sample
Relative Expression (log2-ratio):-5.497958Number of Samples:20 / 18
| Experimental | esophageal adenocarcinoma study 1 |
| Esophageal adenocarcinoma (EAC) samples of affected epithelium recovered by laser capture microdissection technique. | |
| Control | normal esophageal epithelium sample |
| Histologically normal esophageal squamous cell epithelium biopsy samples from patients that were investigated for esophageal pain, but diagnosed as healthy. |
esophagus cancer study 1 (PDX; squamous cell carcinoma, NOS; primary) / esophagus cancer study 1 (PDX; adenocarcinoma, NOS; primary)
Relative Expression (log2-ratio):5.36483Number of Samples:3 / 8
| Experimental | esophagus cancer study 1 (PDX; squamous cell carcinoma, NOS; primary) |
| Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary squamous cell carcinoma, NOS of the oesophagus (subcutaneously implanted). | |
| Control | esophagus cancer study 1 (PDX; adenocarcinoma, NOS; primary) |
| Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary adenocarcinoma, NOS of the oesophagus (subcutaneously implanted). |
expO cervical cancer study 1 (squamous cell carcinoma, keratinizing type, NOS; primary) / expO cervical cancer study 1 (mucinous adenocarcinoma, endocervical type; primary)
Relative Expression (log2-ratio):5.337694Number of Samples:3 / 2
| Experimental | expO cervical cancer study 1 (squamous cell carcinoma, keratinizing type, NOS; primary) |
| Primary tumor tissue samples obtained from the cervix uteri of patients with squamous cell carcinoma, keratinizing type (NOS). | |
| Control | expO cervical cancer study 1 (mucinous adenocarcinoma, endocervical type; primary) |
| Primary tumor tissue samples obtained from the cervix uteri of patients with mucinous adenocarcinoma, endocervical type. |
esophageal squamous cell carcinoma study 1 / esophageal adenocarcinoma study 1
Relative Expression (log2-ratio):5.2741213Number of Samples:8 / 20
| Experimental | esophageal squamous cell carcinoma study 1 |
| Esophageal squamous cell carcinoma (ESCC) biopsy samples from chemotherapy-naive patients with histological grading G1 (well differentiated) and UICC stage II and III, which undergone esophagectomy. | |
| Control | esophageal adenocarcinoma study 1 |
| Esophageal adenocarcinoma (EAC) samples of affected epithelium recovered by laser capture microdissection technique. |
expO cervical cancer study 1 (squamous cell carcinoma, keratinizing type, NOS; primary) / expO cervical cancer study 1 (adenocarcinoma, NOS; primary)
Relative Expression (log2-ratio):4.9857826Number of Samples:3 / 6
| Experimental | expO cervical cancer study 1 (squamous cell carcinoma, keratinizing type, NOS; primary) |
| Primary tumor tissue samples obtained from the cervix uteri of patients with squamous cell carcinoma, keratinizing type (NOS). | |
| Control | expO cervical cancer study 1 (adenocarcinoma, NOS; primary) |
| Primary tumor tissue samples obtained from the cervix uteri of patients with adenocarcinoma (NOS). |
lung cancer study 1 (PDX; squamous cell carcinoma, NOS; primary) / lung cancer study 1 (PDX; pseudosarcomatous carcinoma; primary)
Relative Expression (log2-ratio):4.5541353Number of Samples:43 / 4
| Experimental | lung cancer study 1 (PDX; squamous cell carcinoma, NOS; primary) |
| Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary squamous cell carcinoma, NOS of the lung (subcutaneously implanted). | |
| Control | lung cancer study 1 (PDX; pseudosarcomatous carcinoma; primary) |
| Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary pseudosarcomatous carcinoma of the lung (subcutaneously implanted). |
Organism: Homo sapiens
Gene: 38608_at
Selected probe(set): 206400_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 38608_at (206400_at) across 6674 perturbations tested by GENEVESTIGATOR:
melanoma study 34 (metastatic) / melanoma study 34 (in situ)
Relative Expression (log2-ratio):-7.35742Number of Samples:40 / 2
| Experimental | melanoma study 34 (metastatic) |
| Metastatic tumor tissue sample obtained from the patients with metastatic malignant melanoma of the skin. Metastatic samples composed of 22 macroscopic lymph node metastases, 16 subcutaneous metastases and 2 solid organ metastases (adrenal and brain). | |
| Control | melanoma study 34 (in situ) |
| Tumor tissue from the skin of patients with melanoma in situ. |
melanoma study 34 (metastatic) / normal skin tissue
Relative Expression (log2-ratio):-7.3206863Number of Samples:40 / 4
| Experimental | melanoma study 34 (metastatic) |
| Metastatic tumor tissue sample obtained from the patients with metastatic malignant melanoma of the skin. Metastatic samples composed of 22 macroscopic lymph node metastases, 16 subcutaneous metastases and 2 solid organ metastases (adrenal and brain). | |
| Control | normal skin tissue |
| Normal skin tissue. |
expO cervical cancer study 1 (squamous cell carcinoma, keratinizing type, NOS; primary) / expO cervical cancer study 1 (adenosquamous carcinoma; primary)
Relative Expression (log2-ratio):6.5827513Number of Samples:3 / 2
| Experimental | expO cervical cancer study 1 (squamous cell carcinoma, keratinizing type, NOS; primary) |
| Primary tumor tissue samples obtained from the cervix uteri of patients with squamous cell carcinoma, keratinizing type (NOS). | |
| Control | expO cervical cancer study 1 (adenosquamous carcinoma; primary) |
| Primary tumor tissue samples obtained from the cervix uteri of patients with adenosquamous carcinoma. |
expO skin cancer study 1 (squamous cell carcinoma, NOS; metastatic) / expO skin cancer study 1 (malignant melanoma, NOS; metastatic)
Relative Expression (log2-ratio):5.726631Number of Samples:2 / 9
| Experimental | expO skin cancer study 1 (squamous cell carcinoma, NOS; metastatic) |
| Metastatic tumor tissue samples obtained from patients with primary squamous cell carcinoma (NOS) of the skin. | |
| Control | expO skin cancer study 1 (malignant melanoma, NOS; metastatic) |
| Metastatic tumor tissue samples obtained from patients with primary malignant melanoma (NOS) of the skin. |
esophageal adenocarcinoma study 1 / normal esophageal epithelium sample
Relative Expression (log2-ratio):-5.497958Number of Samples:20 / 18
| Experimental | esophageal adenocarcinoma study 1 |
| Esophageal adenocarcinoma (EAC) samples of affected epithelium recovered by laser capture microdissection technique. | |
| Control | normal esophageal epithelium sample |
| Histologically normal esophageal squamous cell epithelium biopsy samples from patients that were investigated for esophageal pain, but diagnosed as healthy. |
esophagus cancer study 1 (PDX; squamous cell carcinoma, NOS; primary) / esophagus cancer study 1 (PDX; adenocarcinoma, NOS; primary)
Relative Expression (log2-ratio):5.36483Number of Samples:3 / 8
| Experimental | esophagus cancer study 1 (PDX; squamous cell carcinoma, NOS; primary) |
| Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary squamous cell carcinoma, NOS of the oesophagus (subcutaneously implanted). | |
| Control | esophagus cancer study 1 (PDX; adenocarcinoma, NOS; primary) |
| Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary adenocarcinoma, NOS of the oesophagus (subcutaneously implanted). |
expO cervical cancer study 1 (squamous cell carcinoma, keratinizing type, NOS; primary) / expO cervical cancer study 1 (mucinous adenocarcinoma, endocervical type; primary)
Relative Expression (log2-ratio):5.337694Number of Samples:3 / 2
| Experimental | expO cervical cancer study 1 (squamous cell carcinoma, keratinizing type, NOS; primary) |
| Primary tumor tissue samples obtained from the cervix uteri of patients with squamous cell carcinoma, keratinizing type (NOS). | |
| Control | expO cervical cancer study 1 (mucinous adenocarcinoma, endocervical type; primary) |
| Primary tumor tissue samples obtained from the cervix uteri of patients with mucinous adenocarcinoma, endocervical type. |
esophageal squamous cell carcinoma study 1 / esophageal adenocarcinoma study 1
Relative Expression (log2-ratio):5.2741213Number of Samples:8 / 20
| Experimental | esophageal squamous cell carcinoma study 1 |
| Esophageal squamous cell carcinoma (ESCC) biopsy samples from chemotherapy-naive patients with histological grading G1 (well differentiated) and UICC stage II and III, which undergone esophagectomy. | |
| Control | esophageal adenocarcinoma study 1 |
| Esophageal adenocarcinoma (EAC) samples of affected epithelium recovered by laser capture microdissection technique. |
expO cervical cancer study 1 (squamous cell carcinoma, keratinizing type, NOS; primary) / expO cervical cancer study 1 (adenocarcinoma, NOS; primary)
Relative Expression (log2-ratio):4.9857826Number of Samples:3 / 6
| Experimental | expO cervical cancer study 1 (squamous cell carcinoma, keratinizing type, NOS; primary) |
| Primary tumor tissue samples obtained from the cervix uteri of patients with squamous cell carcinoma, keratinizing type (NOS). | |
| Control | expO cervical cancer study 1 (adenocarcinoma, NOS; primary) |
| Primary tumor tissue samples obtained from the cervix uteri of patients with adenocarcinoma (NOS). |
lung cancer study 1 (PDX; squamous cell carcinoma, NOS; primary) / lung cancer study 1 (PDX; pseudosarcomatous carcinoma; primary)
Relative Expression (log2-ratio):4.5541353Number of Samples:43 / 4
| Experimental | lung cancer study 1 (PDX; squamous cell carcinoma, NOS; primary) |
| Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary squamous cell carcinoma, NOS of the lung (subcutaneously implanted). | |
| Control | lung cancer study 1 (PDX; pseudosarcomatous carcinoma; primary) |
| Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary pseudosarcomatous carcinoma of the lung (subcutaneously implanted). |