Organism: Homo sapiens
Gene: 38650_at
Selected probe(set): 211959_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 38650_at (211959_at) across 6674 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):-8.533697
Number of Samples:3 / 3

Experimental	HIF-1a/HIF-2a depletion study 1 (hypoxia; HK2)
	Proximal tubule epithelial cell line HK-2 with shRNA-mediated stable knock-down of HIF-1a and HIF-2a (Hypoxia-inducible factor 1-alpha and Hypoxia-inducible factor 2-alpha) 24 hours after treatment with hypoxia (20% O2). HK-2 cells were cultured in DMEM/F-12 supplemented with 10% fetal calf serum (FCS), 1% ITS, hydrocortisone, and antibiotics. The cells were incubated at 37 °C.
Control	HIF-1a/HIF-2a depletion study 1 (normoxia; AB81)
	Human podocyte cells AB81 with shRNA-mediated stable knock-down of HIF-1a and HIF-2a (Hypoxia-inducible factor 1-alpha and Hypoxia-inducible factor 2-alpha) 24 hours after treatment with normoxia (20% O2). Conditionally immortalized human podocytes AB81 were cultured under permissive conditions (33 °C) in RPMI-1640 supplemented with 10% FBS, antibiotics, and 1% ITS. Differentiation was induced by thermoshift to 37 °C in 6-well plates.

Relative Expression (log2-ratio):7.343583
Number of Samples:4 / 2

Experimental	basal cell carcinoma study 3
	Primary tumor tissue from the eyelid of patients with basal cell carcinoma (BCC).
Control	normal epidermal keratinocytes
	Normal human epidermal keratinocytes (NHEK) (Kurabo Ind., Ltd., Osaka, Japan) cultured in HuMedia-KB2 medium at 37°C in humidified air containing 5% CO2.

Relative Expression (log2-ratio):7.225978
Number of Samples:3 / 3

Experimental	TGF-ß study 5 (late)
	Human A549 cells were treated with 5ng/ml porcine TGF-ß after serum-starving for 24h. Samples were taken 72 hours after TGF-ß treatment.
Control	untreated A549 cell sample
	A549 cells were grown for 24 hours. Samples were taken immediately before TGF-ß treatment.

Relative Expression (log2-ratio):6.987734
Number of Samples:8 / 9

Experimental	hepatocyte (ESC)
	Hepatocyte-like cells differentiated from embryonic stem cells (ESC)
Control	Hep-G2
	Human primary cancer cell line derived from the liver of a patient with hepatocellular carcinoma. Synonyms:HEP-G2; Hep G2; HEP G2; HepG2; HEPG2 Cellosaurus code:

Relative Expression (log2-ratio):-6.905124
Number of Samples:3 / 3

Experimental	AsPC-1
	Human xenograft derived metastatic cancer cell line derived from mouse xenografts initiated with metastatic cells from the ascites derived from a 62 years old female Caucasian patient with pancreatic adenocarcinoma. Synonyms:AsPc-1; Aspc-1; ASPC-1; As-PC1; ASPC1; AsPC1; Aspc1; AsPc1 Cellosaurus code:
Control	BxPC-3
	Human pancreatic adenocarcinoma cell line derived from a 61 years old female patient. Synonyms:BxPc-3; BXPC-3; Bx-PC3; BXPC3; BxPC3; BxPc3 Cellosaurus code:

Relative Expression (log2-ratio):6.1489234
Number of Samples:3 / 3

Experimental	TGF-β study 12
	NCI-H358 cells were cultured for 2-3 weeks in the presence of 2ng/ml of TGF-β, to induce epithelial-mesenchymal transition (EMT). 24 hours prior analysis cells were re-seeded without TGF-β.
Control	untreated NCI-H358 cell sample
	NCI-H358 cells grown in standard media.

Relative Expression (log2-ratio):5.95765
Number of Samples:3 / 6

Experimental	SDF study 4
	MDA Mb231 cells treated with 75nM stromal derived factor (SDF; Cxcl12) for 6h.
Control	untreated MDA Mb231 cell sample
	Untreated MDA Mb231 cells harvested after 6h.

Relative Expression (log2-ratio):5.6114817
Number of Samples:9 / 3

Experimental	TGF-ß study 5 (intermediate)
	Human A549 cells were treated with 5ng/ml porcine TGF-ß after serum-starving for 24h. Samples were taken 8, 16, 24 hours after TGF-ß treatment.
Control	untreated A549 cell sample
	A549 cells were grown for 24 hours. Samples were taken immediately before TGF-ß treatment.

Relative Expression (log2-ratio):5.5163736
Number of Samples:3 / 8

Experimental	esophagus cancer study 1 (PDX; squamous cell carcinoma, NOS; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary squamous cell carcinoma, NOS of the oesophagus (subcutaneously implanted).
Control	esophagus cancer study 1 (PDX; adenocarcinoma, NOS; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary adenocarcinoma, NOS of the oesophagus (subcutaneously implanted).

Relative Expression (log2-ratio):-5.461297
Number of Samples:3 / 2

Experimental	prostate cancer study 8 (p. canc)
	CD26+ FACS sorted prostate neoplasm cell (p. canc) samples from patients with primary prostate cancer collected after radical prostatectomy.
Control	prostate cancer study 8 (ptasc)
	CD90+ FACS sorted prostate tumor-associated stromal cell (ptasc) samples from patients with primary prostate cancer collected after radical prostatectomy.