TOP TEN perturbations for 38687_at (Homo sapiens)
Organism: Homo sapiens
Gene: 38687_at
Selected probe(set): 209001_s_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 38687_at (209001_s_at) across 6674 perturbations tested by GENEVESTIGATOR:
oncolytic herpes simplex virus study 2 / mock infected peripheral nerve sheath tumor (S462) cell sample
Relative Expression (log2-ratio):-2.5223732Number of Samples:3 / 3
Experimental | oncolytic herpes simplex virus study 2 |
Human malignant peripheral nerve sheath tumor (S462) cells infected with G207, an ICP34.5-deleted oncolytic herpes simplex virus (oHSV) for 6 hours. | |
Control | mock infected peripheral nerve sheath tumor (S462) cell sample |
Human malignant peripheral nerve sheath tumor (S462) cells mock infected for 6 hours. |
sarcoidosis study 6 (orbital adipose tissue) / normal orbital adipose tissue
Relative Expression (log2-ratio):-2.2398624Number of Samples:7 / 22
Experimental | sarcoidosis study 6 (orbital adipose tissue) |
Orbital adipose tissue samples obtained from patients who suffered from sarcoidosis. Biopsies were formalin-fixed and paraffin-embedded. | |
Control | normal orbital adipose tissue |
Normal orbital adipose tissue samples. Samples were obtained from subjects with no history of orbital disease at the time of surgery such as fat typically excised and discarded as part of routine blepharoplasty or retrobulbar fat that is snared with the eye during enucleation. Biopsies were formalin-fixed and paraffin-embedded. |
nonspecific orbital inflammatory disease study 1 (lacrimal gland tissue) / normal lacrimal gland tissue
Relative Expression (log2-ratio):-2.214507Number of Samples:42 / 7
Experimental | nonspecific orbital inflammatory disease study 1 (lacrimal gland tissue) |
Lacrimal gland tissue samples obtained from patients who suffered from nonspecific orbital inflammatory disease (NSOI). Biopsies were formalin-fixed and paraffin-embedded. | |
Control | normal lacrimal gland tissue |
Normal lacrimal gland tissue samples. The control tissue was obtained during surgery on eyes with non-inflamed orbits, such as blepharoplasties and enucleations. Biopsies were formalin-fixed and paraffin-embedded. |
coronary artery disease study 2 / normal endothelial progenitor cell (133+) sample
Relative Expression (log2-ratio):2.0145397Number of Samples:9 / 3
Experimental | coronary artery disease study 2 |
133+ endothelial progenitor cells obtained from patients with coronary artery disease (CAD) prior to exercise. CAD patients were enrolled in a cardiac rehabilitation program. Medical management was stable for at least 1 month prior to program participation. Baseline testing was performed after an overnight fast (except for water). | |
Control | normal endothelial progenitor cell (133+) sample |
133+ endothelial progenitor cells obtained from healthy subjects. |
F. tularensis study 1 (novicida) / uninfected peripheral blood monocyte sample
Relative Expression (log2-ratio):-1.9996386Number of Samples:4 / 6
Experimental | F. tularensis study 1 (novicida) |
Peripheral blood monocytes infected with the Francisella tularensis subspecies novicida isolate U112 (100 MOI) for 24 hours. | |
Control | uninfected peripheral blood monocyte sample |
Peripheral blood monocytes uninfected. |
sarcoidosis study 6 (lacrimal gland tissue) / normal lacrimal gland tissue
Relative Expression (log2-ratio):-1.8766594Number of Samples:12 / 7
Experimental | sarcoidosis study 6 (lacrimal gland tissue) |
Lacrimal gland tissue samples obtained from patients who suffered from sarcoidosis. Biopsies were formalin-fixed and paraffin-embedded. | |
Control | normal lacrimal gland tissue |
Normal lacrimal gland tissue samples. The control tissue was obtained during surgery on eyes with non-inflamed orbits, such as blepharoplasties and enucleations. Biopsies were formalin-fixed and paraffin-embedded. |
stem cell differentiation study 41 (T3pi) / undifferentiated hES-T3 cell sample
Relative Expression (log2-ratio):1.8591661Number of Samples:2 / 3
Experimental | stem cell differentiation study 41 (T3pi) |
Sample of pancreatic islet-like cell clusters differentiated from human embryonic stem cells T3 with female karyotype. | |
Control | undifferentiated hES-T3 cell sample |
Undifferentiated human embryonic stem cells T3. |
F. tularensis study 1 (tularensis Schu S4) / uninfected peripheral blood monocyte sample
Relative Expression (log2-ratio):-1.8503637Number of Samples:4 / 6
Experimental | F. tularensis study 1 (tularensis Schu S4) |
Peripheral blood monocytes infected with the Schu S4 isolate of Francisella tularensis (100 MOI) for 24 hours. | |
Control | uninfected peripheral blood monocyte sample |
Peripheral blood monocytes uninfected. |
brefeldin A study 1 (0.5ug/ml; p53HCT116) / untreated p53HCT116 cell sample
Relative Expression (log2-ratio):1.8020353Number of Samples:2 / 3
Experimental | brefeldin A study 1 (0.5ug/ml; p53HCT116) |
Derived human colon carcinoma cell line p53HCT116 with knockout gene for p53 was treated with 0.5 ug/ml brefeldin-A for 24 hours in McCOYs 5A medium supplemented with 10% heat inactivated FBS. ATC code:--- | |
Control | untreated p53HCT116 cell sample |
Derived human colon carcinoma cell line p53HCT116 with knockout gene for p53 was grown in McCOYs 5A medium supplemented with 10% heat inactivated FBS. |
ovarian tumor study 30 (PDX; transitional cell carcinoma, NOS; primary) / ovarian tumor study 30 (PDX; mixed tumor, malignant, NOS; primary)
Relative Expression (log2-ratio):1.7987442Number of Samples:2 / 2
Experimental | ovarian tumor study 30 (PDX; transitional cell carcinoma, NOS; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary transitional cell carcinoma, NOS of the ovary (subcutaneously implanted). | |
Control | ovarian tumor study 30 (PDX; mixed tumor, malignant, NOS; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary mixed tumor, malignant, NOS of the ovary (subcutaneously implanted). |