TOP TEN perturbations for 38692_at (Homo sapiens)
Organism: Homo sapiens
Gene: 38692_at
Selected probe(set): 209272_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 38692_at (209272_at) across 6674 perturbations tested by GENEVESTIGATOR:
Treg activation study 1 (280min) / unstimulated regulatory T-cell sample
Relative Expression (log2-ratio):3.4670658Number of Samples:2 / 2
Experimental | Treg activation study 1 (280min) |
Regulatory T-cells were stimulated for 280min with anti-CD3/anti-CD28/IL-2 (100U/ml). Treg were sorted as CD4+ CD25high cells from peripheral blood of healthy donors. | |
Control | unstimulated regulatory T-cell sample |
Unstimulated regulatory T-cell sample derived from sorted CD4+ CD25high cells from peripheral blood of healthy donors. |
Treg activation study 1 (300min) / unstimulated regulatory T-cell sample
Relative Expression (log2-ratio):3.4626265Number of Samples:2 / 2
Experimental | Treg activation study 1 (300min) |
Regulatory T-cells were stimulated for 300min with anti-CD3/anti-CD28/IL-2 (100U/ml). Treg were sorted as CD4+ CD25high cells from peripheral blood of healthy donors. | |
Control | unstimulated regulatory T-cell sample |
Unstimulated regulatory T-cell sample derived from sorted CD4+ CD25high cells from peripheral blood of healthy donors. |
T-helper activation study 1 (120min) / unstimulated helper T-cell sample
Relative Expression (log2-ratio):3.2639427Number of Samples:2 / 2
Experimental | T-helper activation study 1 (120min) |
Alloantigen specific helper T-cells were stimulated for 120min with anti-CD3/anti-CD28/IL-2 (100U/ml). T-helper cells were sorted as CD4+ CD25- cells from peripheral blood of healthy donors. | |
Control | unstimulated helper T-cell sample |
Unstimulated alloantigen specific helper T-cell sample derived from sorted CD4+ CD25- cells from peripheral blood of healthy donors. |
T-helper activation study 1 (100min) / unstimulated helper T-cell sample
Relative Expression (log2-ratio):3.1379662Number of Samples:2 / 2
Experimental | T-helper activation study 1 (100min) |
Alloantigen specific helper T-cells were stimulated for 100min with anti-CD3/anti-CD28/IL-2 (100U/ml). T-helper cells were sorted as CD4+ CD25- cells from peripheral blood of healthy donors. | |
Control | unstimulated helper T-cell sample |
Unstimulated alloantigen specific helper T-cell sample derived from sorted CD4+ CD25- cells from peripheral blood of healthy donors. |
Treg activation study 1 (340min) / unstimulated regulatory T-cell sample
Relative Expression (log2-ratio):3.1343393Number of Samples:2 / 2
Experimental | Treg activation study 1 (340min) |
Regulatory T-cells were stimulated for 340min with anti-CD3/anti-CD28/IL-2 (100U/ml). Treg were sorted as CD4+ CD25high cells from peripheral blood of healthy donors. | |
Control | unstimulated regulatory T-cell sample |
Unstimulated regulatory T-cell sample derived from sorted CD4+ CD25high cells from peripheral blood of healthy donors. |
Treg activation study 1 (180min) / unstimulated regulatory T-cell sample
Relative Expression (log2-ratio):3.018631Number of Samples:2 / 2
Experimental | Treg activation study 1 (180min) |
Regulatory T-cells were stimulated for 180min with anti-CD3/anti-CD28/IL-2 (100U/ml). Treg were sorted as CD4+ CD25high cells from peripheral blood of healthy donors. | |
Control | unstimulated regulatory T-cell sample |
Unstimulated regulatory T-cell sample derived from sorted CD4+ CD25high cells from peripheral blood of healthy donors. |
IL-4; GM-CSF study 1 (early) / untreated monocyte sample
Relative Expression (log2-ratio):2.99613Number of Samples:6 / 12
Experimental | IL-4; GM-CSF study 1 (early) |
Monocytes, cultured with vehicle (DMSO/ethanol) and 500 U/ml IL-4 and 800 U/ml GM-CSF for 6 hours. | |
Control | untreated monocyte sample |
Freshly isolated human monocytes from healthy donors. |
T-helper activation study 1 (140min) / unstimulated helper T-cell sample
Relative Expression (log2-ratio):2.9660187Number of Samples:2 / 2
Experimental | T-helper activation study 1 (140min) |
Alloantigen specific helper T-cells were stimulated for 140min with anti-CD3/anti-CD28/IL-2 (100U/ml). T-helper cells were sorted as CD4+ CD25- cells from peripheral blood of healthy donors. | |
Control | unstimulated helper T-cell sample |
Unstimulated alloantigen specific helper T-cell sample derived from sorted CD4+ CD25- cells from peripheral blood of healthy donors. |
Treg activation study 1 (140min) / unstimulated regulatory T-cell sample
Relative Expression (log2-ratio):2.9517984Number of Samples:2 / 2
Experimental | Treg activation study 1 (140min) |
Regulatory T-cells were stimulated for 140min with anti-CD3/anti-CD28/IL-2 (100U/ml). Treg were sorted as CD4+ CD25high cells from peripheral blood of healthy donors. | |
Control | unstimulated regulatory T-cell sample |
Unstimulated regulatory T-cell sample derived from sorted CD4+ CD25high cells from peripheral blood of healthy donors. |
Treg activation study 1 (160min) / unstimulated regulatory T-cell sample
Relative Expression (log2-ratio):2.9083042Number of Samples:2 / 2
Experimental | Treg activation study 1 (160min) |
Regulatory T-cells were stimulated for 160min with anti-CD3/anti-CD28/IL-2 (100U/ml). Treg were sorted as CD4+ CD25high cells from peripheral blood of healthy donors. | |
Control | unstimulated regulatory T-cell sample |
Unstimulated regulatory T-cell sample derived from sorted CD4+ CD25high cells from peripheral blood of healthy donors. |