TOP TEN perturbations for 38692_at (Homo sapiens)

Organism: Homo sapiens
Gene: 38692_at
Selected probe(set): 209272_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 38692_at (209272_at) across 6674 perturbations tested by GENEVESTIGATOR:

Treg activation study 1 (280min) / unstimulated regulatory T-cell sample

Relative Expression (log2-ratio):3.4670658
Number of Samples:2 / 2
Experimental Treg activation study 1 (280min)
Regulatory T-cells were stimulated for 280min with anti-CD3/anti-CD28/IL-2 (100U/ml). Treg were sorted as CD4+ CD25high cells from peripheral blood of healthy donors.
Control unstimulated regulatory T-cell sample
Unstimulated regulatory T-cell sample derived from sorted CD4+ CD25high cells from peripheral blood of healthy donors.

Treg activation study 1 (300min) / unstimulated regulatory T-cell sample

Relative Expression (log2-ratio):3.4626265
Number of Samples:2 / 2
Experimental Treg activation study 1 (300min)
Regulatory T-cells were stimulated for 300min with anti-CD3/anti-CD28/IL-2 (100U/ml). Treg were sorted as CD4+ CD25high cells from peripheral blood of healthy donors.
Control unstimulated regulatory T-cell sample
Unstimulated regulatory T-cell sample derived from sorted CD4+ CD25high cells from peripheral blood of healthy donors.

T-helper activation study 1 (120min) / unstimulated helper T-cell sample

Relative Expression (log2-ratio):3.2639427
Number of Samples:2 / 2
Experimental T-helper activation study 1 (120min)
Alloantigen specific helper T-cells were stimulated for 120min with anti-CD3/anti-CD28/IL-2 (100U/ml). T-helper cells were sorted as CD4+ CD25- cells from peripheral blood of healthy donors.
Control unstimulated helper T-cell sample
Unstimulated alloantigen specific helper T-cell sample derived from sorted CD4+ CD25- cells from peripheral blood of healthy donors.

T-helper activation study 1 (100min) / unstimulated helper T-cell sample

Relative Expression (log2-ratio):3.1379662
Number of Samples:2 / 2
Experimental T-helper activation study 1 (100min)
Alloantigen specific helper T-cells were stimulated for 100min with anti-CD3/anti-CD28/IL-2 (100U/ml). T-helper cells were sorted as CD4+ CD25- cells from peripheral blood of healthy donors.
Control unstimulated helper T-cell sample
Unstimulated alloantigen specific helper T-cell sample derived from sorted CD4+ CD25- cells from peripheral blood of healthy donors.

Treg activation study 1 (340min) / unstimulated regulatory T-cell sample

Relative Expression (log2-ratio):3.1343393
Number of Samples:2 / 2
Experimental Treg activation study 1 (340min)
Regulatory T-cells were stimulated for 340min with anti-CD3/anti-CD28/IL-2 (100U/ml). Treg were sorted as CD4+ CD25high cells from peripheral blood of healthy donors.
Control unstimulated regulatory T-cell sample
Unstimulated regulatory T-cell sample derived from sorted CD4+ CD25high cells from peripheral blood of healthy donors.

Treg activation study 1 (180min) / unstimulated regulatory T-cell sample

Relative Expression (log2-ratio):3.018631
Number of Samples:2 / 2
Experimental Treg activation study 1 (180min)
Regulatory T-cells were stimulated for 180min with anti-CD3/anti-CD28/IL-2 (100U/ml). Treg were sorted as CD4+ CD25high cells from peripheral blood of healthy donors.
Control unstimulated regulatory T-cell sample
Unstimulated regulatory T-cell sample derived from sorted CD4+ CD25high cells from peripheral blood of healthy donors.

IL-4; GM-CSF study 1 (early) / untreated monocyte sample

Relative Expression (log2-ratio):2.99613
Number of Samples:6 / 12
Experimental IL-4; GM-CSF study 1 (early)
Monocytes, cultured with vehicle (DMSO/ethanol) and 500 U/ml IL-4 and 800 U/ml GM-CSF for 6 hours.
Control untreated monocyte sample
Freshly isolated human monocytes from healthy donors.

T-helper activation study 1 (140min) / unstimulated helper T-cell sample

Relative Expression (log2-ratio):2.9660187
Number of Samples:2 / 2
Experimental T-helper activation study 1 (140min)
Alloantigen specific helper T-cells were stimulated for 140min with anti-CD3/anti-CD28/IL-2 (100U/ml). T-helper cells were sorted as CD4+ CD25- cells from peripheral blood of healthy donors.
Control unstimulated helper T-cell sample
Unstimulated alloantigen specific helper T-cell sample derived from sorted CD4+ CD25- cells from peripheral blood of healthy donors.

Treg activation study 1 (140min) / unstimulated regulatory T-cell sample

Relative Expression (log2-ratio):2.9517984
Number of Samples:2 / 2
Experimental Treg activation study 1 (140min)
Regulatory T-cells were stimulated for 140min with anti-CD3/anti-CD28/IL-2 (100U/ml). Treg were sorted as CD4+ CD25high cells from peripheral blood of healthy donors.
Control unstimulated regulatory T-cell sample
Unstimulated regulatory T-cell sample derived from sorted CD4+ CD25high cells from peripheral blood of healthy donors.

Treg activation study 1 (160min) / unstimulated regulatory T-cell sample

Relative Expression (log2-ratio):2.9083042
Number of Samples:2 / 2
Experimental Treg activation study 1 (160min)
Regulatory T-cells were stimulated for 160min with anti-CD3/anti-CD28/IL-2 (100U/ml). Treg were sorted as CD4+ CD25high cells from peripheral blood of healthy donors.
Control unstimulated regulatory T-cell sample
Unstimulated regulatory T-cell sample derived from sorted CD4+ CD25high cells from peripheral blood of healthy donors.