TOP TEN perturbations for 38699_at (Homo sapiens)
Organism: Homo sapiens
Gene: 38699_at
Selected probe(set): 212664_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 38699_at (212664_at) across 6674 perturbations tested by GENEVESTIGATOR:
brain tumor study 1 (ependymoma) / normal brain tissue
Relative Expression (log2-ratio):-4.372698Number of Samples:46 / 12
Experimental | brain tumor study 1 (ependymoma) |
Primary tumor tissue sample from the brain of patients with ependymoma. | |
Control | normal brain tissue |
Histologically normal and non-neoplastic tissue sample from different brain anatomical sites of patients with primary brain tumors. |
brain tumor study 1 (medulloblastoma) / normal brain tissue
Relative Expression (log2-ratio):-4.1947947Number of Samples:22 / 12
Experimental | brain tumor study 1 (medulloblastoma) |
Primary tumor tissue sample from the brain of patients with medulloblastoma. | |
Control | normal brain tissue |
Histologically normal and non-neoplastic tissue sample from different brain anatomical sites of patients with primary brain tumors. |
medulloblastoma study 1 / non-tumor brain tissue
Relative Expression (log2-ratio):-3.8728514Number of Samples:17 / 9
Experimental | medulloblastoma study 1 |
Primary tumor tissue sample from the infratentorial brain of pediatric patients with classical medulloblastoma. | |
Control | non-tumor brain tissue |
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor. |
glioma study 17 (glioblastoma; unsorted) / non-tumor cortical tissue
Relative Expression (log2-ratio):-3.572173Number of Samples:2 / 4
Experimental | glioma study 17 (glioblastoma; unsorted) |
Brain cells isolated from high grade glioblastoma (grade IV). Tumor tissue was dissociated using enzymatic treatment and all cells were used for RNA isolation. | |
Control | non-tumor cortical tissue |
Cortical tissue obtained from patients with epilepsy, but without any manifested brain cancer. The tissue was dissociated using enzymatic treatment, but all brain cell types were used for analyses. |
glioma study 16 (astrocytoma) / normal brain tissue
Relative Expression (log2-ratio):-3.3531265Number of Samples:8 / 2
Experimental | glioma study 16 (astrocytoma) |
Primary astrocytoma tissues obtained from the operating room. Tumors were diagnosed and graded according to the current WHO classification (grade III-IV). | |
Control | normal brain tissue |
Normal brain tissue sample from healthy donors. |
glioma study 16 (secondary glioblastoma) / normal brain tissue
Relative Expression (log2-ratio):-3.3227005Number of Samples:3 / 2
Experimental | glioma study 16 (secondary glioblastoma) |
Secondary glioma tissues obtained from the operating room. Tumors were diagnosed and graded according to the current WHO classification (grade IV). | |
Control | normal brain tissue |
Normal brain tissue sample from healthy donors. |
atypical teratoid/rhabdoid tumor study 1 / non-tumor brain tissue
Relative Expression (log2-ratio):-3.2655516Number of Samples:20 / 9
Experimental | atypical teratoid/rhabdoid tumor study 1 |
Primary tumor tissue sample from the brain of pediatric patients with atypical teratoid/rhabdoid tumor (AT/RT). | |
Control | non-tumor brain tissue |
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor. |
medulloblastoma study 2 / non-tumor brain tissue
Relative Expression (log2-ratio):-3.1817207Number of Samples:4 / 9
Experimental | medulloblastoma study 2 |
Primary tumor tissue sample from the infratentorial brain of pediatric patients with large-cell anaplastic medulloblastoma. | |
Control | non-tumor brain tissue |
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor. |
Alzheimer's disease study 6 / normal large stellate neuron (entorhinal cortex)
Relative Expression (log2-ratio):-3.179329Number of Samples:10 / 12
Experimental | Alzheimer's disease study 6 |
Large stellate neurons of the entorhinal cortex, collected from layer II of clinically and neuropathologically classified late-onset Alzheimer´s disease afflicted individuals. Subjects in this group had a Braak stage of V or VI with a CERAD score of moderate or frequent. | |
Control | normal large stellate neuron (entorhinal cortex) |
Large stellate neurons of the entorhinal cortex, collected from layer II of clinically classified as neurologically normal individuals. Subjects in this group had a Braak stage ranging from I to II with a infrequent Consortium to Establish a Registry for Alzheimer's Disease (CERAD) neuritic plaque density. |
glioma study 27 (glioblastoma, NOS) / glioma study 27 (pilocytic astrocytoma)
Relative Expression (log2-ratio):-3.1574717Number of Samples:4 / 2
Experimental | glioma study 27 (glioblastoma, NOS) |
Primary tumor samples from resected brain tissues of patients with glioblastoma, NOS(WHO grade IV astrocytoma). | |
Control | glioma study 27 (pilocytic astrocytoma) |
Primary tumor samples from resected brain tissues of patients with pilocytic astrocytoma (WHO grade I astrocytoma). |