TOP TEN perturbations for 38700_at (Homo sapiens)
Organism: Homo sapiens
Gene: 38700_at
Selected probe(set): 200621_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 38700_at (200621_at) across 6674 perturbations tested by GENEVESTIGATOR:
prostate cancer study 1 (meta.) / benign prostate tissue
Relative Expression (log2-ratio):-3.8599405Number of Samples:6 / 6
Experimental | prostate cancer study 1 (meta.) |
Metastatic prostate cancer samples. | |
Control | benign prostate tissue |
Benign prostate samples. |
retina pigment epithelium study 2 (fetal) / retina pigment epithelium study 1 (fetal)
Relative Expression (log2-ratio):3.6255827Number of Samples:12 / 6
Experimental | retina pigment epithelium study 2 (fetal) |
Human cultured fetal retina pigment epithelium samples obtained at gestation age between week 16-18. | |
Control | retina pigment epithelium study 1 (fetal) |
Human native fetal retina pigment epithelium samples obtained at gestation age between week 16-18. |
prostate cancer study 1 (meta.) / prostate cancer study 1 (prim.)
Relative Expression (log2-ratio):-3.5013323Number of Samples:6 / 7
Experimental | prostate cancer study 1 (meta.) |
Metastatic prostate cancer samples. | |
Control | prostate cancer study 1 (prim.) |
Primary prostate cancer samples. |
small cell lung cancer study 4 (1. gen. PDX) / small cell lung cancer study 4 (XCL from PDX)
Relative Expression (log2-ratio):3.3648977Number of Samples:4 / 3
Experimental | small cell lung cancer study 4 (1. gen. PDX) |
A small cell lung cancer (SCLC) primary xenograft tumor tissue samples derived from three chemo-naive patients (LX22; LX33 and LX36; first generation-1. gen.). The discarded tissue obtained during bronchoscopy of SCLC patients was used to generate a xenograft. Aseptically resuspended tumour cells were injected s.c. in the flanks of nonobese diabetic/severe combined immunodeficient mice (NOD/SCID). The mice were sacrificed when the P0 tumors reached 1cm in diameter. | |
Control | small cell lung cancer study 4 (XCL from PDX) |
Xenograft-derived cell lines (XCL) established from a small cell lung carcinoma (SCLC) patient derived xenografts (PDX). The discarded tissue from three chemo-naive patients (LX22; LX33 and LX35) was obtained during bronchoscopy and used to generate a xenograft. Aseptically resuspended tumour cells were injected s.c. in the flanks of nonobese diabetic/severe combined immunodeficient mice. The mice were sacrificed when the P0 tumors reached 1cm in diameter. Obtained cells were used for conventional cell culture cultivation. |
retina pigment epithelium study 1 (adult) / retina pigment epithelium study 1 (fetal)
Relative Expression (log2-ratio):3.267047Number of Samples:2 / 6
Experimental | retina pigment epithelium study 1 (adult) |
Postmortem human native retina pigment epithelium samples from adult individuals. | |
Control | retina pigment epithelium study 1 (fetal) |
Human native fetal retina pigment epithelium samples obtained at gestation age between week 16-18. |
medulloblastoma study 2 / non-tumor brain tissue
Relative Expression (log2-ratio):-3.1130362Number of Samples:4 / 9
Experimental | medulloblastoma study 2 |
Primary tumor tissue sample from the infratentorial brain of pediatric patients with large-cell anaplastic medulloblastoma. | |
Control | non-tumor brain tissue |
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor. |
small cell lung cancer study 4 (2. gen. PDX) / small cell lung cancer study 4 (1. gen. PDX)
Relative Expression (log2-ratio):-2.9905138Number of Samples:4 / 4
Experimental | small cell lung cancer study 4 (2. gen. PDX) |
Xenografts (secondary) tumor tissue samples derived from a PDX-derived cell lines. A patient derived xenograft (PDX)-derived cell lines were grown under conventional tissue culture conditions for six months and then reimplanted to generate secondary xenografts (2. gen.). | |
Control | small cell lung cancer study 4 (1. gen. PDX) |
A small cell lung cancer (SCLC) primary xenograft tumor tissue samples derived from three chemo-naive patients (LX22; LX33 and LX36; first generation-1. gen.). The discarded tissue obtained during bronchoscopy of SCLC patients was used to generate a xenograft. Aseptically resuspended tumour cells were injected s.c. in the flanks of nonobese diabetic/severe combined immunodeficient mice (NOD/SCID). The mice were sacrificed when the P0 tumors reached 1cm in diameter. |
brain tumor study 1 (medulloblastoma) / brain tumor study 1 (ependymoma)
Relative Expression (log2-ratio):-2.9760551Number of Samples:22 / 46
Experimental | brain tumor study 1 (medulloblastoma) |
Primary tumor tissue sample from the brain of patients with medulloblastoma. | |
Control | brain tumor study 1 (ependymoma) |
Primary tumor tissue sample from the brain of patients with ependymoma. |
atypical teratoid/rhabdoid tumor study 1 / non-tumor brain tissue
Relative Expression (log2-ratio):-2.9483814Number of Samples:20 / 9
Experimental | atypical teratoid/rhabdoid tumor study 1 |
Primary tumor tissue sample from the brain of pediatric patients with atypical teratoid/rhabdoid tumor (AT/RT). | |
Control | non-tumor brain tissue |
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor. |
brain tumor study 1 (medulloblastoma) / normal brain tissue
Relative Expression (log2-ratio):-2.9151907Number of Samples:22 / 12
Experimental | brain tumor study 1 (medulloblastoma) |
Primary tumor tissue sample from the brain of patients with medulloblastoma. | |
Control | normal brain tissue |
Histologically normal and non-neoplastic tissue sample from different brain anatomical sites of patients with primary brain tumors. |