TOP TEN perturbations for 38707_r_at (Homo sapiens)
Organism: Homo sapiens
Gene: 38707_r_at
Selected probe(set): 38707_r_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 38707_r_at (38707_r_at) across 6674 perturbations tested by GENEVESTIGATOR:
atopic dermatitis study 21 (non-lesional; whole skin) / normal skin tissue
Relative Expression (log2-ratio):-1.8005991Number of Samples:5 / 6
Experimental | atopic dermatitis study 21 (non-lesional; whole skin) |
Non-lesional full thickness skin samples isolated from patient with moderate-to-severe atopic dermatitis by laser capture microdissection. Patients' cohort characteristics: 3 males and 2 females; age 27-59 years (mean age: 39.4 years); SCORing of Atopic Dermatitis index (SCORAD) ranging from 45-65; total IgE: 14-1821 kU/l; eosinophilic count: 1.4-11.8 %. | |
Control | normal skin tissue |
Full thickness skin samples isolated from healthy subjects by laser capture microdissection. |
breast cancer study 8 (metastatic) / normal breast tissue
Relative Expression (log2-ratio):1.6506577Number of Samples:2 / 4
Experimental | breast cancer study 8 (metastatic) |
Human metastatic infiltrating ductal carcinoma sample of the breast derived from lymph nodes of a female patient with breast cancer. | |
Control | normal breast tissue |
Normal human breast samples of healthy female individuals. |
ovarian tumor study 11 (low grade) / normal ovarian surface epithelial cell sample
Relative Expression (log2-ratio):-1.4763575Number of Samples:11 / 6
Experimental | ovarian tumor study 11 (low grade) |
Human microdissected tumor cells from the ovary of patients with low grade serous carcinoma. | |
Control | normal ovarian surface epithelial cell sample |
Human microdissected ovarian surface epithelial cell sample from the ovary of healthy individuals. |
small cell lung cancer study 4 (XCL from CDX) / small cell lung cancer study 4 (cell line)
Relative Expression (log2-ratio):-1.4737082Number of Samples:11 / 4
Experimental | small cell lung cancer study 4 (XCL from CDX) |
Xenograft-derived cell lines (XCL) established from a small cell lung carcinoma (SCLC) publicly available cell lines derived xenografts (CDX derived cell lines). Xenografts were grown in the flanks of a nude mice. Obtained cells were cultivated under conventional tissue culture conditions. | |
Control | small cell lung cancer study 4 (cell line) |
Various small cell lung cancer (SCLC) publicly available cell lines samples. |
cadmium study 1 (brief) / untreated NPrEC cell sample
Relative Expression (log2-ratio):1.3814697Number of Samples:2 / 2
Experimental | cadmium study 1 (brief) |
After 72h of starvation, NPrEC cells were briefly exposed to 2.5 uM CdCl2. ATC code:--- | |
Control | untreated NPrEC cell sample |
After 72h of starvation, NPrEC cells were briefly exposed to complete medium without CdCl2. |
HCC study 27 (young; validation) / HCC study 27 (elder; validation)
Relative Expression (log2-ratio):-1.3094559Number of Samples:21 / 10
Experimental | HCC study 27 (young; validation) |
Primary tumor tissue samples obtained from the liver of young patients (≤ 40 years old) with hepatocellular carcinoma assigned to a validation cohort. | |
Control | HCC study 27 (elder; validation) |
Primary tumor tissue samples obtained from the liver of elder patients (> 40 years old) with hepatocellular carcinoma assigned to a validation cohort. |
ovarian tumor study 17 / normal ovarian surface epithelial cell sample
Relative Expression (log2-ratio):-1.1534634Number of Samples:9 / 10
Experimental | ovarian tumor study 17 |
Human epithelial tumor cell samples from the ovary of patients with primary clear cell carcinoma. Samples were derived by laser capture microdissection (LCM). | |
Control | normal ovarian surface epithelial cell sample |
Human epithelial cell samples from histopathological normal and non-cancerous ovary tissue from donors with non-cancerous, benign gynecological diseases. |
HCC study 27 (elder; validation) / HCC study 27 (elder; training)
Relative Expression (log2-ratio):1.1427212Number of Samples:10 / 32
Experimental | HCC study 27 (elder; validation) |
Primary tumor tissue samples obtained from the liver of elder patients (> 40 years old) with hepatocellular carcinoma assigned to a validation cohort. | |
Control | HCC study 27 (elder; training) |
Primary tumor tissue samples obtained from the liver of elder patients (> 40 years old) with hepatocellular carcinoma assigned to a training cohort. |
stem cell differentiation study 41 (hES-T3 EB) / undifferentiated hES-T3 cell sample
Relative Expression (log2-ratio):-1.1249886Number of Samples:2 / 3
Experimental | stem cell differentiation study 41 (hES-T3 EB) |
Sample of embryonic bodies (EB) differentiated from human embryonic stem cells T3 with female karyotype. | |
Control | undifferentiated hES-T3 cell sample |
Undifferentiated human embryonic stem cells T3. |
ovarian tumor study 11 (high grade) / ovarian tumor study 11 (low grade)
Relative Expression (log2-ratio):1.102149Number of Samples:22 / 11
Experimental | ovarian tumor study 11 (high grade) |
Human microdissected tumor cells from the ovary of patients with high grade serous carcinoma. | |
Control | ovarian tumor study 11 (low grade) |
Human microdissected tumor cells from the ovary of patients with low grade serous carcinoma. |