TOP TEN perturbations for 38714_at (Homo sapiens)
Organism: Homo sapiens
Gene: 38714_at
Selected probe(set): 205838_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 38714_at (205838_at) across 6674 perturbations tested by GENEVESTIGATOR:
sickle cell disease study 2 (Globin red.) / normal blood sample
Relative Expression (log2-ratio):5.3181963Number of Samples:5 / 5
Experimental | sickle cell disease study 2 (Globin red.) |
Whole blood samples of patients with sickle cell disease collected in PAXgene tubes. RNA was extracted using the PAXgene™ Blood RNA System Kit followed by an on-column DNase digestion. Then globin mRNA was depleted using the GLOBINclear™-Human kit. | |
Control | normal blood sample |
Whole blood samples of healthy volunteers collected in PAXgene tubes. RNA was extracted using the PAXgeneTM Blood RNA System Kit including an on-column DNase digestion. Then globin mRNA was depleted using the GLOBINclearTM-Human kit. |
sickle cell disease study 2 (Pax) / normal blood sample
Relative Expression (log2-ratio):5.1016912Number of Samples:5 / 5
Experimental | sickle cell disease study 2 (Pax) |
Whole blood samples of patients with sickle cell disease collected in PAXgene tubes. RNA was extracted using the PAXgene™ Blood RNA System Kit followed by an on-column DNase digestion step. | |
Control | normal blood sample |
Whole blood samples of healthy volunteers collected in PAXgene tubes. RNA was extracted using the PAXgeneTM Blood RNA System Kit followed by an on-column DNase digestion step. |
B-CLL study 5 / normal bone marrow sample
Relative Expression (log2-ratio):-4.161889Number of Samples:441 / 74
Experimental | B-CLL study 5 |
Bone marrow samples of patients with B-cell chronic lymphocytic leukemia (B-CLL). | |
Control | normal bone marrow sample |
Non-leukemic and healthy bone marrow sample. |
precursor-B-ALL study 1 (t(11q23)) / normal bone marrow sample
Relative Expression (log2-ratio):-3.7762384Number of Samples:70 / 74
Experimental | precursor-B-ALL study 1 (t(11q23)) |
Bone marrow samples of patients with precursor B-ALL (t(11q23)/MLL). | |
Control | normal bone marrow sample |
Non-leukemic and healthy bone marrow sample. |
AML study 1 (t(8;21)(q22;q22)) / normal bone marrow sample
Relative Expression (log2-ratio):-3.5822935Number of Samples:40 / 74
Experimental | AML study 1 (t(8;21)(q22;q22)) |
Bone marrow samples of patients with acute myeloid leukemia (AML) with genetic aberration (t(8;21)(q22;q22)). | |
Control | normal bone marrow sample |
Non-leukemic and healthy bone marrow sample. |
T-ALL study 1 / normal bone marrow sample
Relative Expression (log2-ratio):-3.421976Number of Samples:174 / 74
Experimental | T-ALL study 1 |
Bone marrow samples of patients with T-ALL. | |
Control | normal bone marrow sample |
Non-leukemic and healthy bone marrow sample. |
c-ALL/pre-B-ALL study 1 (t(9;22)(q34,q11)) / normal bone marrow sample
Relative Expression (log2-ratio):-3.3321524Number of Samples:121 / 74
Experimental | c-ALL/pre-B-ALL study 1 (t(9;22)(q34,q11)) |
Bone marrow samples of patients with c-ALL/pre-B-ALL (t(9;22)(q34,q11)/BCR-ABL). | |
Control | normal bone marrow sample |
Non-leukemic and healthy bone marrow sample. |
AML study 1 (t(11q23)) / normal bone marrow sample
Relative Expression (log2-ratio):-3.329587Number of Samples:38 / 74
Experimental | AML study 1 (t(11q23)) |
Bone marrow samples of patients with acute myeloid leukemia (AML) with genetic aberration (t(11q23)/MLL). | |
Control | normal bone marrow sample |
Non-leukemic and healthy bone marrow sample. |
mature B-ALL study 1 (t(8;14)) / normal bone marrow sample
Relative Expression (log2-ratio):-3.3077822Number of Samples:13 / 74
Experimental | mature B-ALL study 1 (t(8;14)) |
Bone marrow samples of patients with mature B-ALL (t(8;14)). | |
Control | normal bone marrow sample |
Non-leukemic and healthy bone marrow sample. |
AML study 1 (t(15;17)(q22;q11-12)) / normal bone marrow sample
Relative Expression (log2-ratio):-3.28901Number of Samples:36 / 74
Experimental | AML study 1 (t(15;17)(q22;q11-12)) |
Bone marrow samples of patients with acute promyelocytic leukemia [subtype of acute myeloid leukemia (AML)] with genetic aberration (t(15;17)(q22;q11-12)/PML-RARα and variations). | |
Control | normal bone marrow sample |
Non-leukemic and healthy bone marrow sample. |