TOP TEN perturbations for 38715_at (Homo sapiens)
Organism: Homo sapiens
Gene: 38715_at
Selected probe(set): 214407_x_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 38715_at (214407_x_at) across 6674 perturbations tested by GENEVESTIGATOR:
systemic onset JIA study 4 / juvenile enthesitis related arthritis study 2 (ERA)
Relative Expression (log2-ratio):6.748664Number of Samples:3 / 3
Experimental | systemic onset JIA study 4 |
Peripheral blood mononuclear cell (PBMC) samples from children with systemic onset of juvenile rheumatoid arthritis (JIA). | |
Control | juvenile enthesitis related arthritis study 2 (ERA) |
Peripheral blood mononuclear cell (PBMC) samples from children with enthesitis related arthritis (ERA). |
systemic onset JIA study 4 / oligoarticular JIA study 3
Relative Expression (log2-ratio):6.3771877Number of Samples:3 / 12
Experimental | systemic onset JIA study 4 |
Peripheral blood mononuclear cell (PBMC) samples from children with systemic onset of juvenile rheumatoid arthritis (JIA). | |
Control | oligoarticular JIA study 3 |
Peripheral blood mononuclear cell (PBMC) samples from children with persistent oligoarthritis (oligoarticular JIA). |
systemic onset JIA study 5 / oligoarticular JIA study 2
Relative Expression (log2-ratio):6.3533163Number of Samples:3 / 12
Experimental | systemic onset JIA study 5 |
Peripheral blood mononuclear cell (PBMC) samples from children with recent onset and systemic onset of juvenile rheumatoid arthritis (SoJIA). All patients were free of disease modifying antirheumatic drugs or biologics. Subjects were classified according to ILAR criteria. Patients were enrolled in the study very early in the disease course, hence difference between disease onset and age at sampling is small (<4-8 month). | |
Control | oligoarticular JIA study 2 |
Peripheral blood mononuclear cell (PBMC) samples from children with recent onset of persistent oligoarticular juvenile idiopathic arthritis (JIA). All patients were free of disease modifying antirheumatic drugs or biologics. Subjects were classified according to ILAR criteria. Patients were enrolled in the study very early in the disease course, hence difference between disease onset and age at sampling is small (<4-8 month). |
systemic onset JIA study 5 / normal PBMC sample
Relative Expression (log2-ratio):6.107894Number of Samples:3 / 27
Experimental | systemic onset JIA study 5 |
Peripheral blood mononuclear cell (PBMC) samples from children with recent onset and systemic onset of juvenile rheumatoid arthritis (SoJIA). All patients were free of disease modifying antirheumatic drugs or biologics. Subjects were classified according to ILAR criteria. Patients were enrolled in the study very early in the disease course, hence difference between disease onset and age at sampling is small (<4-8 month). | |
Control | normal PBMC sample |
Peripheral blood mononuclear cell (PBMC) samples from healthy children. |
systemic onset JIA study 4 / normal PBMC sample
Relative Expression (log2-ratio):5.9820156Number of Samples:3 / 27
Experimental | systemic onset JIA study 4 |
Peripheral blood mononuclear cell (PBMC) samples from children with systemic onset of juvenile rheumatoid arthritis (JIA). | |
Control | normal PBMC sample |
Peripheral blood mononuclear cell (PBMC) samples from healthy children. |
systemic onset JIA study 5 / polyarticular JIA study 4 (RF negative)
Relative Expression (log2-ratio):5.9568367Number of Samples:3 / 17
Experimental | systemic onset JIA study 5 |
Peripheral blood mononuclear cell (PBMC) samples from children with recent onset and systemic onset of juvenile rheumatoid arthritis (SoJIA). All patients were free of disease modifying antirheumatic drugs or biologics. Subjects were classified according to ILAR criteria. Patients were enrolled in the study very early in the disease course, hence difference between disease onset and age at sampling is small (<4-8 month). | |
Control | polyarticular JIA study 4 (RF negative) |
Peripheral blood mononuclear cell (PBMC) samples from children with recent onset of polyarticular juvenile idiopathic arthritis, rheumatoid factor negative (polyJIA, RF neg.). All patients were free of disease modifying antirheumatic drugs or biologics. Subjects were classified according to ILAR criteria. Patients were enrolled in the study very early in the disease course, hence difference between disease onset and age at sampling is small (<4-8 month). |
systemic onset JIA study 4 / polyarticular JIA study 6
Relative Expression (log2-ratio):5.7088223Number of Samples:3 / 14
Experimental | systemic onset JIA study 4 |
Peripheral blood mononuclear cell (PBMC) samples from children with systemic onset of juvenile rheumatoid arthritis (JIA). | |
Control | polyarticular JIA study 6 |
Peripheral blood mononuclear cell (PBMC) samples from children with rheumatoid factor negative polyarthritis (RF- polyarthritis/RF- polyarticular JIA). |
B-CLL study 5 / normal bone marrow sample
Relative Expression (log2-ratio):-4.614958Number of Samples:441 / 74
Experimental | B-CLL study 5 |
Bone marrow samples of patients with B-cell chronic lymphocytic leukemia (B-CLL). | |
Control | normal bone marrow sample |
Non-leukemic and healthy bone marrow sample. |
systemic onset JIA study 3 / polyarticular JIA study 3 (RF positive)
Relative Expression (log2-ratio):4.0786858Number of Samples:18 / 15
Experimental | systemic onset JIA study 3 |
Peripheral blood mononuclear cell (PBMC) samples from children with systemic onset of juvenile rheumatoid arthritis (JIA). All patients were free of disease modifying antirheumatic drugs. | |
Control | polyarticular JIA study 3 (RF positive) |
Peripheral blood mononuclear cell (PBMC) samples from children with rheumatoid factor negative (RFpos) polyarticular juvenile rheumatoid arthritis. All patients were free of disease modifying antirheumatic drugs. |
sickle cell disease study 2 (Pax) / normal blood sample
Relative Expression (log2-ratio):4.0749187Number of Samples:5 / 5
Experimental | sickle cell disease study 2 (Pax) |
Whole blood samples of patients with sickle cell disease collected in PAXgene tubes. RNA was extracted using the PAXgene™ Blood RNA System Kit followed by an on-column DNase digestion step. | |
Control | normal blood sample |
Whole blood samples of healthy volunteers collected in PAXgene tubes. RNA was extracted using the PAXgeneTM Blood RNA System Kit followed by an on-column DNase digestion step. |