TOP TEN perturbations for 38719_at (Homo sapiens)
Organism: Homo sapiens
Gene: 38719_at
Selected probe(set): 202395_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 38719_at (202395_at) across 6674 perturbations tested by GENEVESTIGATOR:
HIV-associated neurocognitive disorder study 7 (normal) / HIV-associated neurocognitive disorder study 6 (normal)
Relative Expression (log2-ratio):3.2045527Number of Samples:2 / 2
Experimental | HIV-associated neurocognitive disorder study 7 (normal) |
Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with normal brain pathology. The patients received antiretroviral therapy (ART). | |
Control | HIV-associated neurocognitive disorder study 6 (normal) |
Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with normal brain pathology. The patients did not receive any antiretroviral therapy (ART). |
atypical teratoid/rhabdoid tumor study 1 / non-tumor brain tissue
Relative Expression (log2-ratio):-2.7583008Number of Samples:20 / 9
Experimental | atypical teratoid/rhabdoid tumor study 1 |
Primary tumor tissue sample from the brain of pediatric patients with atypical teratoid/rhabdoid tumor (AT/RT). | |
Control | non-tumor brain tissue |
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor. |
brain tumor study 1 (ependymoma) / normal brain tissue
Relative Expression (log2-ratio):-2.754466Number of Samples:46 / 12
Experimental | brain tumor study 1 (ependymoma) |
Primary tumor tissue sample from the brain of patients with ependymoma. | |
Control | normal brain tissue |
Histologically normal and non-neoplastic tissue sample from different brain anatomical sites of patients with primary brain tumors. |
glioma study 5 / non-tumor brain tissue
Relative Expression (log2-ratio):-2.6860018Number of Samples:12 / 9
Experimental | glioma study 5 |
Primary tumor tissue sample from the supratentorial brain of pediatric patients with glioblastoma multiformae. | |
Control | non-tumor brain tissue |
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor. |
F. tularensis study 1 (novicida) / uninfected peripheral blood monocyte sample
Relative Expression (log2-ratio):-2.618083Number of Samples:4 / 6
Experimental | F. tularensis study 1 (novicida) |
Peripheral blood monocytes infected with the Francisella tularensis subspecies novicida isolate U112 (100 MOI) for 24 hours. | |
Control | uninfected peripheral blood monocyte sample |
Peripheral blood monocytes uninfected. |
Alzheimer's disease study 8 / normal pyramidal neuron (middle temporal gyrus)
Relative Expression (log2-ratio):-2.528448Number of Samples:15 / 12
Experimental | Alzheimer's disease study 8 |
Cortical layer III pyramidal neurons of the middle temporal gyrus of clinically and neuropathologically classified late-onset Alzheimer´s disease afflicted individuals. Subjects in this group had a Braak stage of V or VI with a CERAD score of moderate or frequent. | |
Control | normal pyramidal neuron (middle temporal gyrus) |
Cortical layer III pyramidal neurons of the middle temporal gyrus of clinically classified as neurologically normal individuals. Subjects in this group had a Braak stage ranging from I to II with a infrequent Consortium to Establish a Registry for Alzheimer's Disease (CERAD) neuritic plaque density. |
zalypsis study 2 / untreated OPM1 cell sample
Relative Expression (log2-ratio):-2.4806614Number of Samples:2 / 2
Experimental | zalypsis study 2 |
OPM1 multiple myeloma cells treated in vitro with zalypsis (5 nM), a novel marine-derived compound with potent antimyeloma activity. Cells were harvested at the beginning of induction of cell death (15-20% cell death as assessed by Annexin V-FITC staining). ATC code:--- | |
Control | untreated OPM1 cell sample |
OPM1 multiple myeloma cells untreated. |
HIV-associated neurocognitive disorder study 7 (normal) / normal genu sample
Relative Expression (log2-ratio):2.3174849Number of Samples:2 / 8
Experimental | HIV-associated neurocognitive disorder study 7 (normal) |
Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with normal brain pathology. The patients received antiretroviral therapy (ART). | |
Control | normal genu sample |
Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from healthy subjects. |
medulloblastoma study 2 / non-tumor brain tissue
Relative Expression (log2-ratio):-2.3136463Number of Samples:4 / 9
Experimental | medulloblastoma study 2 |
Primary tumor tissue sample from the infratentorial brain of pediatric patients with large-cell anaplastic medulloblastoma. | |
Control | non-tumor brain tissue |
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor. |
Parkinson's disease study 6 / normal pars reticulata tissue
Relative Expression (log2-ratio):-2.2698288Number of Samples:3 / 4
Experimental | Parkinson's disease study 6 |
Pars reticulata tissue from patients with Parkinson's disease. | |
Control | normal pars reticulata tissue |
Normal pars reticulata tissue. |