TOP TEN perturbations for 38746_at (Homo sapiens)
Organism: Homo sapiens
Gene: 38746_at
Selected probe(set): 204990_s_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 38746_at (204990_s_at) across 6674 perturbations tested by GENEVESTIGATOR:
expO skin cancer study 1 (squamous cell carcinoma, NOS; metastatic) / expO skin cancer study 1 (malignant melanoma, NOS; metastatic)
Relative Expression (log2-ratio):4.719407Number of Samples:2 / 9
Experimental | expO skin cancer study 1 (squamous cell carcinoma, NOS; metastatic) |
Metastatic tumor tissue samples obtained from patients with primary squamous cell carcinoma (NOS) of the skin. | |
Control | expO skin cancer study 1 (malignant melanoma, NOS; metastatic) |
Metastatic tumor tissue samples obtained from patients with primary malignant melanoma (NOS) of the skin. |
brain tumor study 1 (medulloblastoma) / brain tumor study 1 (ependymoma)
Relative Expression (log2-ratio):-3.6809006Number of Samples:22 / 46
Experimental | brain tumor study 1 (medulloblastoma) |
Primary tumor tissue sample from the brain of patients with medulloblastoma. | |
Control | brain tumor study 1 (ependymoma) |
Primary tumor tissue sample from the brain of patients with ependymoma. |
TNF-ɑ; TGF-ß2 study 1 (intermediate) / untreated ARPE-19 cell sample
Relative Expression (log2-ratio):-3.5466986Number of Samples:6 / 3
Experimental | TNF-ɑ; TGF-ß2 study 1 (intermediate) |
ARPE-19 retina pigment epithelial cell samples treated with TNF-ɑ (10 ng/ml) and TGF-ß2 (5 ng/ml). Samples were taken 16 and 24 hours after treatment. | |
Control | untreated ARPE-19 cell sample |
Untreated ARPE-19 retina pigment epithelial cell samples harvested before adding TNF-ɑ (10 ng/ml) and TGF-ß2 (5 ng/ml). |
ovarian tumor study 11 (low grade) / normal ovarian surface epithelial cell sample
Relative Expression (log2-ratio):3.456606Number of Samples:11 / 6
Experimental | ovarian tumor study 11 (low grade) |
Human microdissected tumor cells from the ovary of patients with low grade serous carcinoma. | |
Control | normal ovarian surface epithelial cell sample |
Human microdissected ovarian surface epithelial cell sample from the ovary of healthy individuals. |
collecting duct carcinoma study 1 / normal kidney tissue (fetal)
Relative Expression (log2-ratio):3.3483772Number of Samples:2 / 2
Experimental | collecting duct carcinoma study 1 |
Tumor tissue samples from the kidney of patients with collecting duct carcinoma (CDC). | |
Control | normal kidney tissue (fetal) |
Normal fetal kidney tissue samples. |
TNF-ɑ; TGF-ß2 study 1 (late) / untreated ARPE-19 cell sample
Relative Expression (log2-ratio):-3.272954Number of Samples:6 / 3
Experimental | TNF-ɑ; TGF-ß2 study 1 (late) |
ARPE-19 retina pigment epithelial cell samples treated with TNF-ɑ (10 ng/ml) and TGF-ß2 (5 ng/ml). Samples were taken 42 and 60 hours after treatment. | |
Control | untreated ARPE-19 cell sample |
Untreated ARPE-19 retina pigment epithelial cell samples harvested before adding TNF-ɑ (10 ng/ml) and TGF-ß2 (5 ng/ml). |
Merkel cell carcinoma study 3 (primary) / skin squamous cell carcinoma study 6
Relative Expression (log2-ratio):-3.243453Number of Samples:19 / 4
Experimental | Merkel cell carcinoma study 3 (primary) |
Primary tumor tissue from the skin of patients with Merkel cell carcinoma. | |
Control | skin squamous cell carcinoma study 6 |
Primary tumor tissue from the skin of patients with squamous cell carcinoma (SCC). |
melanoma study 34 (metastatic) / normal skin tissue
Relative Expression (log2-ratio):-3.0870485Number of Samples:40 / 4
Experimental | melanoma study 34 (metastatic) |
Metastatic tumor tissue sample obtained from the patients with metastatic malignant melanoma of the skin. Metastatic samples composed of 22 macroscopic lymph node metastases, 16 subcutaneous metastases and 2 solid organ metastases (adrenal and brain). | |
Control | normal skin tissue |
Normal skin tissue. |
lung cancer study 1 (PDX; squamous cell carcinoma, NOS; primary) / lung cancer study 1 (PDX; large cell carcinoma, NOS; primary)
Relative Expression (log2-ratio):3.069337Number of Samples:43 / 4
Experimental | lung cancer study 1 (PDX; squamous cell carcinoma, NOS; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary squamous cell carcinoma, NOS of the lung (subcutaneously implanted). | |
Control | lung cancer study 1 (PDX; large cell carcinoma, NOS; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary large cell carcinoma, NOS of the lung (subcutaneously implanted). |
ovarian tumor study 30 (PDX; carcinoma, NOS; metastatic) / ovarian tumor study 30 (PDX; adenocarcinoma, NOS; primary)
Relative Expression (log2-ratio):-3.0471992Number of Samples:2 / 2
Experimental | ovarian tumor study 30 (PDX; carcinoma, NOS; metastatic) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from a metastasis of patients with primary carcinoma, NOS of the ovary (subcutaneously implanted). Metastatic site of patient tumor sample is not reported. | |
Control | ovarian tumor study 30 (PDX; adenocarcinoma, NOS; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary adenocarcinoma, NOS of the ovary (subcutaneously implanted). |