TOP TEN perturbations for 38821_at (Homo sapiens)
Organism: Homo sapiens
Gene: 38821_at
Selected probe(set): 201701_s_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 38821_at (201701_s_at) across 6674 perturbations tested by GENEVESTIGATOR:
echinomycin study 1 / deferoxamine study 5
Relative Expression (log2-ratio):-5.1714478Number of Samples:3 / 3
Experimental | echinomycin study 1 |
Echinomycin (100nM; 2h) treated human astroglioma (U251) cells, stimulated with deferoxamine (DFO; 300mM; 16h). ATC code:--- | |
Control | deferoxamine study 5 |
Untreated human astroglioma (U251) cells, stimulated with deferoxamine (DFO; 300mM; 16h). ATC code: |
R547 study 1 (24h) / vehicle (DMSO) treated DU145 cell sample
Relative Expression (log2-ratio):-2.981453Number of Samples:2 / 4
Experimental | R547 study 1 (24h) |
Human prostate carcinoma metastatic cell line DU145 treated with the CDK inhibitor R547 [4-amino-2-(1-methanesulfonylpiperidin-4-ylamino) pyrimidin-5-yl]-(2, 3-difluoro-6-methoxyphenyl)methanone (Hoffmann-La Roche compound) for 24 hours at a 3xIC90 concentration of 5.1 μmol/L. ATC code:--- | |
Control | vehicle (DMSO) treated DU145 cell sample |
Human prostate carcinoma metastatic cell line DU145 treated with vehicle (DMSO) for 24 hours. |
sarcoidosis study 6 (orbital adipose tissue) / normal orbital adipose tissue
Relative Expression (log2-ratio):-2.6330109Number of Samples:7 / 22
Experimental | sarcoidosis study 6 (orbital adipose tissue) |
Orbital adipose tissue samples obtained from patients who suffered from sarcoidosis. Biopsies were formalin-fixed and paraffin-embedded. | |
Control | normal orbital adipose tissue |
Normal orbital adipose tissue samples. Samples were obtained from subjects with no history of orbital disease at the time of surgery such as fat typically excised and discarded as part of routine blepharoplasty or retrobulbar fat that is snared with the eye during enucleation. Biopsies were formalin-fixed and paraffin-embedded. |
granulomatosis with polyangiitis study 3 (orbital adipose tissue) / normal orbital adipose tissue
Relative Expression (log2-ratio):-2.2799501Number of Samples:9 / 22
Experimental | granulomatosis with polyangiitis study 3 (orbital adipose tissue) |
Orbital adipose tissue samples obtained from patients who suffered from granulomatosis with polyangiitis (GPA). Biopsies were formalin-fixed and paraffin-embedded. | |
Control | normal orbital adipose tissue |
Normal orbital adipose tissue samples. Samples were obtained from subjects with no history of orbital disease at the time of surgery such as fat typically excised and discarded as part of routine blepharoplasty or retrobulbar fat that is snared with the eye during enucleation. Biopsies were formalin-fixed and paraffin-embedded. |
Merkel cell carcinoma study 3 (primary) / normal skin tissue
Relative Expression (log2-ratio):-2.2191286Number of Samples:19 / 64
Experimental | Merkel cell carcinoma study 3 (primary) |
Primary tumor tissue from the skin of patients with Merkel cell carcinoma. | |
Control | normal skin tissue |
Normal skin samples from healthy donors. |
basal cell carcinoma study 2 / normal skin tissue
Relative Expression (log2-ratio):-2.1934938Number of Samples:2 / 64
Experimental | basal cell carcinoma study 2 |
Primary tumor tissue from the skin of patients with basal cell carcinoma (BCC). | |
Control | normal skin tissue |
Normal skin samples from healthy donors. |
Merkel cell carcinoma study 3 (metastatic) / normal skin tissue
Relative Expression (log2-ratio):-2.0948162Number of Samples:11 / 64
Experimental | Merkel cell carcinoma study 3 (metastatic) |
Metastatic tumor tissue from different metastatic sites (skin, lymph node, parotid gland) of patients with Merkel cell carcinoma of the skin. | |
Control | normal skin tissue |
Normal skin samples from healthy donors. |
nonspecific orbital inflammatory disease study 1 (orbital adipose tissue) / normal orbital adipose tissue
Relative Expression (log2-ratio):-2.0752811Number of Samples:31 / 22
Experimental | nonspecific orbital inflammatory disease study 1 (orbital adipose tissue) |
Orbital adipose tissue samples obtained from patients who suffered from nonspecific orbital inflammatory disease (NSOI). Biopsies were formalin-fixed and paraffin-embedded. | |
Control | normal orbital adipose tissue |
Normal orbital adipose tissue samples. Samples were obtained from subjects with no history of orbital disease at the time of surgery such as fat typically excised and discarded as part of routine blepharoplasty or retrobulbar fat that is snared with the eye during enucleation. Biopsies were formalin-fixed and paraffin-embedded. |
breast cancer study 8 (metastatic) / normal breast tissue
Relative Expression (log2-ratio):-2.0146866Number of Samples:2 / 4
Experimental | breast cancer study 8 (metastatic) |
Human metastatic infiltrating ductal carcinoma sample of the breast derived from lymph nodes of a female patient with breast cancer. | |
Control | normal breast tissue |
Normal human breast samples of healthy female individuals. |
DMN study 1 (24h) / vehicle (DMSO) treated HepG2 cell sample
Relative Expression (log2-ratio):-1.9975567Number of Samples:3 / 7
Experimental | DMN study 1 (24h) |
HepG2 cells exposed to 2mM dimethyl nitrosamine (DMN) in DMSO solvent for 24 hours. ATC code:--- | |
Control | vehicle (DMSO) treated HepG2 cell sample |
HepG2 cells exposed to DMSO solvent for 24 hours. |