Organism: Homo sapiens
Gene: 38849_at
Selected probe(set): 212416_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 38849_at (212416_at) across 6674 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):-2.9219856
Number of Samples:2 / 2

Experimental	zalypsis study 2
	OPM1 multiple myeloma cells treated in vitro with zalypsis (5 nM), a novel marine-derived compound with potent antimyeloma activity. Cells were harvested at the beginning of induction of cell death (15-20% cell death as assessed by Annexin V-FITC staining). ATC code:---
Control	untreated OPM1 cell sample
	OPM1 multiple myeloma cells untreated.

Relative Expression (log2-ratio):-2.5316982
Number of Samples:3 / 3

Experimental	oncolytic herpes simplex virus study 2
	Human malignant peripheral nerve sheath tumor (S462) cells infected with G207, an ICP34.5-deleted oncolytic herpes simplex virus (oHSV) for 6 hours.
Control	mock infected peripheral nerve sheath tumor (S462) cell sample
	Human malignant peripheral nerve sheath tumor (S462) cells mock infected for 6 hours.

Relative Expression (log2-ratio):2.2791166
Number of Samples:3 / 3

Experimental	brefeldin A study 1 (0.5ug/ml; HCT 116)
	Human colon carcinoma cell line HCT116 was treated with 0.5 ug/ml brefeldin-A for 24 hours in McCOYs 5A medium supplemented with 10% heat inactivated FBS. ATC code:---
Control	untreated HCT 116 cell sample
	Human colon carcinoma cell line HCT116 was grown in McCOYs 5A medium supplemented with 10% heat inactivated FBS.

Relative Expression (log2-ratio):1.9476538
Number of Samples:2 / 3

Experimental	brefeldin A study 1 (0.5ug/ml; p53HCT116)
	Derived human colon carcinoma cell line p53HCT116 with knockout gene for p53 was treated with 0.5 ug/ml brefeldin-A for 24 hours in McCOYs 5A medium supplemented with 10% heat inactivated FBS. ATC code:---
Control	untreated p53HCT116 cell sample
	Derived human colon carcinoma cell line p53HCT116 with knockout gene for p53 was grown in McCOYs 5A medium supplemented with 10% heat inactivated FBS.

Relative Expression (log2-ratio):-1.9054041
Number of Samples:6 / 6

Experimental	RAF1 depletion study 2
	RNAi-mediated gene knockdown of RAF1 in colorectal cancer cell line SW-620.
Control	mock transfected SW-620 cell sample
	SW-620 colorectal cell line sample transduced with non-targeting pLKO_NonTarget vector.

Relative Expression (log2-ratio):-1.8877068
Number of Samples:42 / 7

Experimental	nonspecific orbital inflammatory disease study 1 (lacrimal gland tissue)
	Lacrimal gland tissue samples obtained from patients who suffered from nonspecific orbital inflammatory disease (NSOI). Biopsies were formalin-fixed and paraffin-embedded.
Control	normal lacrimal gland tissue
	Normal lacrimal gland tissue samples. The control tissue was obtained during surgery on eyes with non-inflamed orbits, such as blepharoplasties and enucleations. Biopsies were formalin-fixed and paraffin-embedded.

Relative Expression (log2-ratio):-1.879282
Number of Samples:3 / 3

Experimental	LPS study 2
	Cultured THP-1 mononuclear cells were treated with lipopolysaccharide (1 microgram/ml) for 4 hours at 37°C. ATC code:---
Control	untreated THP-1 cell sample
	Cultured THP-1 mononuclear cells were cultured in basal growth media at 37°C.

Relative Expression (log2-ratio):-1.8510742
Number of Samples:4 / 6

Experimental	F. tularensis study 1 (tularensis Schu S4)
	Peripheral blood monocytes infected with the Schu S4 isolate of Francisella tularensis (100 MOI) for 24 hours.
Control	uninfected peripheral blood monocyte sample
	Peripheral blood monocytes uninfected.

Relative Expression (log2-ratio):-1.827568
Number of Samples:6 / 6

Experimental	RAF1 depletion study 2
	RNAi-mediated gene knockdown of RAF1 in colorectal cancer cell line SW-620.
Control	control vector transfected SW-620 cell sample
	SW-620 colorectal cell line sample transduced with empty vector pLKO.

Relative Expression (log2-ratio):-1.7966738
Number of Samples:9 / 22

Experimental	granulomatosis with polyangiitis study 3 (orbital adipose tissue)
	Orbital adipose tissue samples obtained from patients who suffered from granulomatosis with polyangiitis (GPA). Biopsies were formalin-fixed and paraffin-embedded.
Control	normal orbital adipose tissue
	Normal orbital adipose tissue samples. Samples were obtained from subjects with no history of orbital disease at the time of surgery such as fat typically excised and discarded as part of routine blepharoplasty or retrobulbar fat that is snared with the eye during enucleation. Biopsies were formalin-fixed and paraffin-embedded.