Organism: Homo sapiens
Gene: 38851_at
Selected probe(set): 207720_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 38851_at (207720_at) across 6674 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):-7.4099293
Number of Samples:11 / 64

Experimental	Merkel cell carcinoma study 3 (metastatic)
	Metastatic tumor tissue from different metastatic sites (skin, lymph node, parotid gland) of patients with Merkel cell carcinoma of the skin.
Control	normal skin tissue
	Normal skin samples from healthy donors.

Relative Expression (log2-ratio):-7.3371572
Number of Samples:3 / 3

Experimental	wound healing study 2 (ex vivo; DMSO)
	Ex vivo skin samples obtained from healthy donors following reduction surgery of abdomen, and incubated in culture medium containing DMSO for 4 days. To make sure that mainly epidermis was present in the samples, as much dermal tissue as possible was removed by dissection. Skin was sliced into 1x10 mm slices and incubated in keratinocyte medium for four days with 1:1000 fold dilution of DMSO. The cultivation was performed in serum-free keratinocyte medium supplemented with transferrin, hEGF (0.15 ng/mL), 0.5 mg/mL hydrocortisone, gentamicin, amphotericin B, and epinephrine but without insulin.
Control	normal skin tissue (ex vivo)
	Normal skin samples obtained from healthy donors following reduction surgery of abdomen. To make sure that mainly epidermis was present in the samples, as much dermal tissue as possible was removed by dissection.

Relative Expression (log2-ratio):-6.9496956
Number of Samples:40 / 2

Experimental	melanoma study 34 (metastatic)
	Metastatic tumor tissue sample obtained from the patients with metastatic malignant melanoma of the skin. Metastatic samples composed of 22 macroscopic lymph node metastases, 16 subcutaneous metastases and 2 solid organ metastases (adrenal and brain).
Control	melanoma study 34 (in situ)
	Tumor tissue from the skin of patients with melanoma in situ.

Relative Expression (log2-ratio):-6.855219
Number of Samples:40 / 4

Experimental	melanoma study 34 (metastatic)
	Metastatic tumor tissue sample obtained from the patients with metastatic malignant melanoma of the skin. Metastatic samples composed of 22 macroscopic lymph node metastases, 16 subcutaneous metastases and 2 solid organ metastases (adrenal and brain).
Control	normal skin tissue
	Normal skin tissue.

Relative Expression (log2-ratio):-6.758912
Number of Samples:6 / 8

Experimental	skin transplantation study 1 (3d)
	Human skin punch biopsy from patients after skin grafting. Sample was taken at the site of re-epithelialization 3 days after surgery.
Control	normal skin tissue (skin grafting)
	Skin biopsy samples from healthy control subjects after breast or abdomen reduction surgery.

Relative Expression (log2-ratio):6.6812267
Number of Samples:4 / 2

Experimental	basal cell carcinoma study 3
	Primary tumor tissue from the eyelid of patients with basal cell carcinoma (BCC).
Control	normal epidermal keratinocytes
	Normal human epidermal keratinocytes (NHEK) (Kurabo Ind., Ltd., Osaka, Japan) cultured in HuMedia-KB2 medium at 37°C in humidified air containing 5% CO2.

Relative Expression (log2-ratio):-6.5843067
Number of Samples:4 / 6

Experimental	split-thickness skin grafting study 2 (NPWT)
	Skin punch biopsy from patients that underwent split-thickness skin grafting. Sample was taken from the wound site 7 days after grafting. Patients received negative-pressure wound therapy (NPWT) immediately after grafting .
Control	normal skin tissue (skin grafting)
	Skin punch biopsy samples from healthy patients before slit-thickness skin grafting.

Relative Expression (log2-ratio):-6.488268
Number of Samples:19 / 64

Experimental	Merkel cell carcinoma study 3 (primary)
	Primary tumor tissue from the skin of patients with Merkel cell carcinoma.
Control	normal skin tissue
	Normal skin samples from healthy donors.

Relative Expression (log2-ratio):5.7502575
Number of Samples:6 / 3

Experimental	engineered skin substitute study 2 (intermediate)
	Human skin substitutes tissue samples collected after 14 and 28 days after transplantation to athymic mice.
Control	engineered skin substitute study 1 (intermediate)
	Human skin substitutes tissue samples collected after 7 days in culture.

Relative Expression (log2-ratio):5.0407457
Number of Samples:3 / 2

Experimental	engineered skin substitute study 1 (late)
	Human skin substitutes tissue samples collected after 14 days in culture.
Control	engineered skin substitute study 1 (early)
	Human skin substitutes tissue samples collected after 3 days in culture.