Organism: Homo sapiens
Gene: 38889_at
Selected probe(set): 204893_s_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 38889_at (204893_s_at) across 6674 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):-1.8557949
Number of Samples:2 / 10

Experimental	Langerhans cell histiocytosis study 2 (multisystem)
	Langerhans cell histiocytes (LCH, CD207+) samples isolated from LCH lesions of patients with multifocal, multisystem (disseminated) disease. Both patients received chemotherapy. Sites of LCH lesions: subj.ID:1 (skin, lungs, multiple skull, mastoid, gingiva), subj.ID:13 (mandible, skull, vertebrae, recurrent orbit, liver, spleen, pituitary gland).
Control	normal epidermal Langerhans cell sample
	Normal epidermal Langerhans cells (CD207+) were isolated from skin of children donors (age < 18 years). The Langerhans cells were isolated from presumably healthy tissue.

Relative Expression (log2-ratio):-1.5994358
Number of Samples:8 / 10

Experimental	Langerhans cell histiocytosis study 2 (unifocal)
	Langerhans cell histiocytes (LCH, CD207+) samples isolated from LCH lesions of patients with unifocal, single system disease (bone lesion).
Control	normal epidermal Langerhans cell sample
	Normal epidermal Langerhans cells (CD207+) were isolated from skin of children donors (age < 18 years). The Langerhans cells were isolated from presumably healthy tissue.

Relative Expression (log2-ratio):-1.5542183
Number of Samples:3 / 3

Experimental	formaldehyde study 3 (4500ug/ml)
	Bronchial epithelial cells (NHBE) treated with 4500 ug/ml formaldehyde (within range of concentrations reported to induce toxicity in lung epithelial cells and other cell types) for 24 hours. NHBE cells were derived from a 60 year old male non-smoker. ATC code:---
Control	vehicle (EtOH) treated bronchial epithelial cell sample
	Bronchial epithelial cells (NHBE) treated with vehicle (ethanol) at a final concentration of 2% v/v (concentration that ensures >80% cell viability after 24 hours of exposure) for 24 hours. NHBE cells were derived from a 60 year old male non-smoker.

Relative Expression (log2-ratio):1.5323467
Number of Samples:2 / 2

Experimental	HIV-associated neurocognitive disorder study 7 (normal)
	Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with normal brain pathology. The patients received antiretroviral therapy (ART).
Control	HIV-associated neurocognitive disorder study 6 (normal)
	Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with normal brain pathology. The patients did not receive any antiretroviral therapy (ART).

Relative Expression (log2-ratio):1.5074701
Number of Samples:20 / 20

Experimental	IgA nephropathy study 8
	Hand-microdissected glomerular tissue samples derived from kidney biopsies of patients with IgA nephropathy (IgAN). Whole-core patient biopsies were obtained as part of routine renal biopsy procedures.
Control	control glomerulus tissue
	Hand-microdissected glomerular tissue samples derived from kidney biopsies of healthy living kidney transplant donors. The biopsies were taken after reperfusion in the kidney transplant recipient.

Relative Expression (log2-ratio):1.4529839
Number of Samples:4 / 3

Experimental	lung cancer study 1 (PDX; pseudosarcomatous carcinoma; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary pseudosarcomatous carcinoma of the lung (subcutaneously implanted).
Control	lung cancer study 1 (PDX; basaloid carcinoma; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary basaloid carcinoma of the lung (subcutaneously implanted).

Relative Expression (log2-ratio):1.3697739
Number of Samples:4 / 22

Experimental	lung cancer study 1 (PDX; pseudosarcomatous carcinoma; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary pseudosarcomatous carcinoma of the lung (subcutaneously implanted).
Control	lung cancer study 1 (PDX; adenocarcinoma, NOS; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary adenocarcinoma, NOS of the lung (subcutaneously implanted).

Relative Expression (log2-ratio):1.3603935
Number of Samples:4 / 4

Experimental	lung cancer study 1 (PDX; pseudosarcomatous carcinoma; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary pseudosarcomatous carcinoma of the lung (subcutaneously implanted).
Control	lung cancer study 1 (PDX; large cell carcinoma, NOS; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary large cell carcinoma, NOS of the lung (subcutaneously implanted).

Relative Expression (log2-ratio):-1.334938
Number of Samples:4 / 8

Experimental	cutaneous T-cell lymphoma study 1 (tumor phase)
	Lesional skin biopsies from patients with cutaneous T-cell lymphoma in the tumor phase (extranodal).
Control	normal skin tissue
	Skin biopsies from healthy individuals.

Relative Expression (log2-ratio):1.2866116
Number of Samples:3 / 3

Experimental	hair follicle growth study 1 (P5)
	Dermal papilla cells isolated from occipital scalp hair follicles obtained and cultured subsequent in two dimensional culture. Samples were taken at passage 5.
Control	hair follicle growth study 1 (P0)
	Dermal papilla cells isolated from occipital scalp hair follicles obtained and cultured subsequent in two dimensional culture. Samples were taken directly after cell explant outgrowth.