Organism: Homo sapiens
Gene: 38890_at
Selected probe(set): 206350_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 38890_at (206350_at) across 6674 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):-6.5256853
Number of Samples:8 / 12

Experimental	hepatocyte (ESC)
	Hepatocyte-like cells differentiated from embryonic stem cells (ESC)
Control	HepaRG
	Immortalized cancer cell line derived from female patient with hepatocellular carcinoma. Cells can be induced to differentiate into hepatocyte-like cells by exposure to DMSO. Synonyms:Hepa-RG Cellosaurus code:

Relative Expression (log2-ratio):-6.2904797
Number of Samples:9 / 12

Experimental	Hep-G2
	Human primary cancer cell line derived from the liver of a patient with hepatocellular carcinoma. Synonyms:HEP-G2; Hep G2; HEP G2; HepG2; HEPG2 Cellosaurus code:
Control	HepaRG
	Immortalized cancer cell line derived from female patient with hepatocellular carcinoma. Cells can be induced to differentiate into hepatocyte-like cells by exposure to DMSO. Synonyms:Hepa-RG Cellosaurus code:

Relative Expression (log2-ratio):-4.7727375
Number of Samples:5 / 5

Experimental	hepatoblastoma study 1 (NOS)
	Liver tumor tissue samples from children with hepatoblastoma (NOS). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group.
Control	normal liver tissue
	Normal liver tissue samples.

Relative Expression (log2-ratio):-4.3786926
Number of Samples:12 / 5

Experimental	hepatoblastoma study 1 (epithelial mixed)
	Liver tumor tissue samples from children with hepatoblastoma (epithelial type (E-HB); epithelial mixed subtype). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group.
Control	normal liver tissue
	Normal liver tissue samples.

Relative Expression (log2-ratio):-4.0704412
Number of Samples:3 / 12

Experimental	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone study 1 (7500 uM; HepaRG)
	HepaRG cells exposed to 7500 uM 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (dissolved in 0.5% v/v DMSO) for 72 hours. Cells were cultivated in DMSO-containing medium between days 13 - 19 to allow them to differentiate into hepatocyte-like cells and become fully functional. Chemical was added at day 19 of cultivation. Cells were treated with the IC10 determined by a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide test (number of replicates, n = 3). ATC code:---
Control	vehicle (DMSO) treated HepaRG cell sample
	HepaRG cells treated with vehicle (DMSO 0.5% v/v) for 72 hours. Firstly, cells were cultivated in DMSO-containing medium between days 13 - 19 to allow them to differentiate into hepatocyte-like cells and become fully functional. Then the vehicle was added.

Relative Expression (log2-ratio):-3.9494314
Number of Samples:7 / 5

Experimental	hepatoblastoma study 1 (embryonal)
	Liver tumor tissue samples from children with hepatoblastoma (epithelial type (E-HB); embryonal subtype). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group.
Control	normal liver tissue
	Normal liver tissue samples.

Relative Expression (log2-ratio):3.6079063
Number of Samples:3 / 12

Experimental	hepatoblastoma study 1 (crowded fetal)
	Liver tumor tissue samples from children with hepatoblastoma (epithelial type (E-HB); crowded fetal subtype). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group.
Control	hepatoblastoma study 1 (epithelial mixed)
	Liver tumor tissue samples from children with hepatoblastoma (epithelial type (E-HB); epithelial mixed subtype). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group.

Relative Expression (log2-ratio):-3.4618092
Number of Samples:7 / 3

Experimental	breast cancer study 42 (metastase; lymph node)
	Metastatic tumor tissue obtained from the lymph node of patients with primary breast adenocarcinoma.
Control	breast cancer study 42 (metastase; liver)
	Metastatic tumor tissue obtained from the liver of patients with primary breast adenocarcinoma.

Relative Expression (log2-ratio):-3.3914871
Number of Samples:2 / 10

Experimental	HCC study 9 (HBV; HCV)
	Liver tissue biopsy sample from patients with Hepatitis B and C infection related hepatocellular carcinoma (HCC) after resection.
Control	normal liver tissue
	Normal, non-tumor liver tissue.

Relative Expression (log2-ratio):-3.3141537
Number of Samples:13 / 5

Experimental	hepatoblastoma study 1 (mixed embryonal and fetal)
	Liver tumor tissue samples from children with hepatoblastoma (epithelial type (E-HB); mixed embryonal and fetal subtype). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group.
Control	normal liver tissue
	Normal liver tissue samples.