TOP TEN perturbations for 38906_at (Homo sapiens)
Organism: Homo sapiens
Gene: 38906_at
Selected probe(set): 206937_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 38906_at (206937_at) across 6674 perturbations tested by GENEVESTIGATOR:
B-CLL study 5 / normal bone marrow sample
Relative Expression (log2-ratio):-4.3788595Number of Samples:441 / 74
Experimental | B-CLL study 5 |
Bone marrow samples of patients with B-cell chronic lymphocytic leukemia (B-CLL). | |
Control | normal bone marrow sample |
Non-leukemic and healthy bone marrow sample. |
AML study 1 (t(15;17)(q22;q11-12)) / normal bone marrow sample
Relative Expression (log2-ratio):-3.467783Number of Samples:36 / 74
Experimental | AML study 1 (t(15;17)(q22;q11-12)) |
Bone marrow samples of patients with acute promyelocytic leukemia [subtype of acute myeloid leukemia (AML)] with genetic aberration (t(15;17)(q22;q11-12)/PML-RARα and variations). | |
Control | normal bone marrow sample |
Non-leukemic and healthy bone marrow sample. |
AML study 1 (t(11q23)) / normal bone marrow sample
Relative Expression (log2-ratio):-3.3570385Number of Samples:38 / 74
Experimental | AML study 1 (t(11q23)) |
Bone marrow samples of patients with acute myeloid leukemia (AML) with genetic aberration (t(11q23)/MLL). | |
Control | normal bone marrow sample |
Non-leukemic and healthy bone marrow sample. |
mature B-ALL study 1 (t(8;14)) / normal bone marrow sample
Relative Expression (log2-ratio):-3.1910105Number of Samples:13 / 74
Experimental | mature B-ALL study 1 (t(8;14)) |
Bone marrow samples of patients with mature B-ALL (t(8;14)). | |
Control | normal bone marrow sample |
Non-leukemic and healthy bone marrow sample. |
AML study 1 (t(8;21)(q22;q22)) / normal bone marrow sample
Relative Expression (log2-ratio):-3.1215506Number of Samples:40 / 74
Experimental | AML study 1 (t(8;21)(q22;q22)) |
Bone marrow samples of patients with acute myeloid leukemia (AML) with genetic aberration (t(8;21)(q22;q22)). | |
Control | normal bone marrow sample |
Non-leukemic and healthy bone marrow sample. |
precursor-B-ALL study 3 (TEL-AML1) / precursor-B-ALL study 3 (MLL-rearranged)
Relative Expression (log2-ratio):3.0206003Number of Samples:15 / 5
Experimental | precursor-B-ALL study 3 (TEL-AML1) |
Peripheral blood and bone marrow samples of pediatric patients with precursor B-ALL [t(12;21)(p13,q22)/TEL-AML1]. Patients were part of the Nordic Society Of Pediatric Hematology And Oncology Group (NOPHO). | |
Control | precursor-B-ALL study 3 (MLL-rearranged) |
Peripheral blood and bone marrow samples of pediatric patients with precursor B-ALL [t(v;11q23)/MLL rearranged]. Patients were part of the Nordic Society Of Pediatric Hematology And Oncology Group (NOPHO). |
precursor-B-ALL study 1 (t(11q23)) / normal bone marrow sample
Relative Expression (log2-ratio):-3.0191107Number of Samples:70 / 74
Experimental | precursor-B-ALL study 1 (t(11q23)) |
Bone marrow samples of patients with precursor B-ALL (t(11q23)/MLL). | |
Control | normal bone marrow sample |
Non-leukemic and healthy bone marrow sample. |
sickle cell disease study 2 (Globin red.) / normal blood sample
Relative Expression (log2-ratio):2.9014797Number of Samples:5 / 5
Experimental | sickle cell disease study 2 (Globin red.) |
Whole blood samples of patients with sickle cell disease collected in PAXgene tubes. RNA was extracted using the PAXgene™ Blood RNA System Kit followed by an on-column DNase digestion. Then globin mRNA was depleted using the GLOBINclear™-Human kit. | |
Control | normal blood sample |
Whole blood samples of healthy volunteers collected in PAXgene tubes. RNA was extracted using the PAXgeneTM Blood RNA System Kit including an on-column DNase digestion. Then globin mRNA was depleted using the GLOBINclearTM-Human kit. |
T-ALL study 1 / normal bone marrow sample
Relative Expression (log2-ratio):-2.856701Number of Samples:174 / 74
Experimental | T-ALL study 1 |
Bone marrow samples of patients with T-ALL. | |
Control | normal bone marrow sample |
Non-leukemic and healthy bone marrow sample. |
AML study 1 (inv(16)/t(16;16)) / normal bone marrow sample
Relative Expression (log2-ratio):-2.8332577Number of Samples:28 / 74
Experimental | AML study 1 (inv(16)/t(16;16)) |
Bone marrow samples of patients with acute myeloid leukemia (AML) with genetic aberration (inv(16)/t(16;16)). | |
Control | normal bone marrow sample |
Non-leukemic and healthy bone marrow sample. |