TOP TEN perturbations for 38995_at (Homo sapiens)
Organism: Homo sapiens
Gene: 38995_at
Selected probe(set): 204482_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 38995_at (204482_at) across 6674 perturbations tested by GENEVESTIGATOR:
rapidly progressive glomerulonephritis; ANCA-associated vasculitis study 5 (tubulointerstitium) / focal segmental glomerulosclerosis study 9 (glomerulus)
Relative Expression (log2-ratio):-4.6597996Number of Samples:21 / 10
Experimental | rapidly progressive glomerulonephritis; ANCA-associated vasculitis study 5 (tubulointerstitium) |
Tubulointerstitium tissue sample obtained by microdissection from kidney biopsy, from patients suffering from rapidly progressive glomerulonephritis and antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. Donors were positive for ANCA-antibody. Biopsy samples were obtained from the European Renal cDNA Bank-Kroener-Fresenius biopsy bank. All biopsies were stratified by a reference pathologist. | |
Control | focal segmental glomerulosclerosis study 9 (glomerulus) |
Glomeruli tissue sample obtained by microdissection from kidney biopsy, from patients suffering from focal segmental glomerulosclerosis. Biopsy samples were obtained from the European Renal cDNA Bank-Kroener-Fresenius biopsy bank. All biopsies were stratified by a reference pathologist. |
glioma study 17 (glioblastoma; A2B5+) / non-tumor oligodendrocyte progenitor cell sample (cortex)
Relative Expression (log2-ratio):-3.236064Number of Samples:3 / 3
Experimental | glioma study 17 (glioblastoma; A2B5+) |
Oligodendrocyte progenitor cells (OPC) isolated from high grade glioblastoma (grade IV). OPC were isolated using magnetic-activated cell sorting (MACS) with antibodies against A2B5 antigen. Patients were 66 ± 5 years old males. | |
Control | non-tumor oligodendrocyte progenitor cell sample (cortex) |
Oligodendrocyte progenitor cells (OPC) isolated from cortical tissue, which was obtained from patients with epilepsy, but without any manifested brain cancer. OPC were isolated using magnetic-activated cell sorting (MACS) with antibodies against A2B5 antigen. |
breast cancer study 10 (stroma) / noncancerous breast stroma tissue
Relative Expression (log2-ratio):-3.201375Number of Samples:6 / 6
Experimental | breast cancer study 10 (stroma) |
Cancerous breast stroma tissue from female patients associated to primary breast infiltrative ductal carcinoma with stromal invasion. | |
Control | noncancerous breast stroma tissue |
Noncancerous (normal) tissue cell samples after laser-microdissection from female patients with primary breast infiltrative ductal carcinoma with stromal invasion. |
colorectal cancer study 43 (metastase; brain) / colorectal cancer study 43 (metastase; liver)
Relative Expression (log2-ratio):2.9746294Number of Samples:2 / 25
Experimental | colorectal cancer study 43 (metastase; brain) |
Metastatic tumor tissue obtained from the brain of patients with primary colorectal adenocarcinoma. | |
Control | colorectal cancer study 43 (metastase; liver) |
Metastatic tumor tissue obtained from the liver of patients with primary colon adenocarcinoma. |
breast cancer study 8 (primary) / normal breast tissue
Relative Expression (log2-ratio):-2.9271784Number of Samples:13 / 4
Experimental | breast cancer study 8 (primary) |
Human primary infiltrating ductal carcinoma sample of a female patient with breast cancer. | |
Control | normal breast tissue |
Normal human breast samples of healthy female individuals. |
lung adenocarcinoma study 3 (negative) / normal lung tissue
Relative Expression (log2-ratio):-2.9241467Number of Samples:9 / 3
Experimental | lung adenocarcinoma study 3 (negative) |
Primary lung adenocarcinoma samples, with bone marrow negative for early disseminated tumor cells (DTCs). The presence of DTCs can predict the subsequent occurrence of overt metastasis and survival in lung cancer. | |
Control | normal lung tissue |
Normal lung tissue. |
caffeine study 2 (7500uM) / vehicle (medium) treated hepatocyte sample
Relative Expression (log2-ratio):2.8861933Number of Samples:2 / 2
Experimental | caffeine study 2 (7500uM) |
Hepatocytes treated with compound: caffeine (7500uM; CHEMBL113) for 24 hours. ATC code: | |
Control | vehicle (medium) treated hepatocyte sample |
Hepatocytes treated with vehicle (medium) for 24 hours. |
lung adenocarcinoma study 3 (positive) / normal lung tissue
Relative Expression (log2-ratio):-2.8476944Number of Samples:7 / 3
Experimental | lung adenocarcinoma study 3 (positive) |
Primary lung adenocarcinoma samples, with bone marrow positive for early disseminated tumor cells (DTCs). The presence of DTCs can predict the subsequent occurrence of overt metastasis and survival in lung cancer. | |
Control | normal lung tissue |
Normal lung tissue. |
glioma study 17 (astrocytoma; A2B5+) / non-tumor oligodendrocyte progenitor cell sample (cortex)
Relative Expression (log2-ratio):-2.8014832Number of Samples:3 / 3
Experimental | glioma study 17 (astrocytoma; A2B5+) |
Oligodendrocyte progenitor cells (OPC) isolated from low grade astrocytoma (grade II). OPC were isolated using magnetic-activated cell sorting (MACS) with antibodies against A2B5 antigen. Patients were 36 ± 7 years old. | |
Control | non-tumor oligodendrocyte progenitor cell sample (cortex) |
Oligodendrocyte progenitor cells (OPC) isolated from cortical tissue, which was obtained from patients with epilepsy, but without any manifested brain cancer. OPC were isolated using magnetic-activated cell sorting (MACS) with antibodies against A2B5 antigen. |
lung adenocarcinoma study 6 (EGFR mut) / adjacent lung tissue
Relative Expression (log2-ratio):-2.679144Number of Samples:24 / 20
Experimental | lung adenocarcinoma study 6 (EGFR mut) |
Primary tumor sample from patients with stage II adenocarcinoma carrying an EGFR mutation. | |
Control | adjacent lung tissue |
Adjacent and histologically normal, non-tumorous lung tissue samples from patients with lung adenocarcinoma. |