TOP TEN perturbations for 39025_at (Homo sapiens)

Organism: Homo sapiens
Gene: 39025_at
Selected probe(set): 201812_s_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 39025_at (201812_s_at) across 6674 perturbations tested by GENEVESTIGATOR:

glioma study 16 (LN-229) / normal astrocyte sample

Relative Expression (log2-ratio):2.970604
Number of Samples:2 / 3
Experimental glioma study 16 (LN-229)
Human glioma cell line LN229 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37°C and 5% CO2.
Control normal astrocyte sample
Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations.

kidney transplantation study 16 (2 week) / normal natural killer cell (CD56+) sample

Relative Expression (log2-ratio):-2.7910357
Number of Samples:3 / 3
Experimental kidney transplantation study 16 (2 week)
CD56+ natural killer cell samples derived from kidney transplant patients 2 weeks post-transplantation. Samples were collected 2 week after transplantation and administration of immunosuppressive therapy (day 1-4: methylprednisolone (60 mg); 3 doses: rabbit polyclonal anti-thymocyte globulin (ThymoglobulinH; 6 mg/kg); mycophenolate mofetil (CellCeptH); and tacrolimus (PrografH).
Control normal natural killer cell (CD56+) sample
CD56+ natural killer cell samples derived from healthy control subjects.

glioma study 16 (BS-149) / normal astrocyte sample

Relative Expression (log2-ratio):2.7002983
Number of Samples:2 / 3
Experimental glioma study 16 (BS-149)
Human glioma cell line BS149 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37°C and 5% CO2.
Control normal astrocyte sample
Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations.

glioma study 16 (LN-18) / normal astrocyte sample

Relative Expression (log2-ratio):2.4153252
Number of Samples:2 / 3
Experimental glioma study 16 (LN-18)
Human glioma cell line LN018 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37C and 5% CO2.
Control normal astrocyte sample
Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations.

interferon-alpha-kinoid study 1 (30ug; 112d) / untreated whole blood sample

Relative Expression (log2-ratio):2.077321
Number of Samples:3 / 43
Experimental interferon-alpha-kinoid study 1 (30ug; 112d)
Whole blood samples of patients with systemic lupus erythematosus after treatment with interferon-alpha-kinoid (INF-K; inactivated IFNa coupled keyhole limpet hemocyanin as carrier). Patients had 3 doses of 30ug INK-K at day 0, 7 and 58. Sample was taken 112 days after the first application of TNF-K. ATC code:---
Control untreated whole blood sample
Whole blood samples from healthy volunteers.

interferon-alpha-kinoid study 2 (120ug; 168d) / untreated whole blood sample

Relative Expression (log2-ratio):1.9996367
Number of Samples:2 / 43
Experimental interferon-alpha-kinoid study 2 (120ug; 168d)
Whole blood samples of patients with systemic lupus erythematosus after treatment with interferon-alpha-kinoid (INF-K; inactivated IFNa coupled keyhole limpet hemocyanin as carrier). Patients had 4 doses of 120ug INK-K at day 0, 7, 58 and 84. Sample was taken 168 days after the first application of TNF-K. ATC code:---
Control untreated whole blood sample
Whole blood samples from healthy volunteers.

glioma study 16 (LN-215) / normal astrocyte sample

Relative Expression (log2-ratio):1.8964615
Number of Samples:2 / 3
Experimental glioma study 16 (LN-215)
Human glioma cell line LN215 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37°C and 5% CO2.
Control normal astrocyte sample
Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations.

hypoxia study 7 (high altitude) / hypoxia study 7 (sea level)

Relative Expression (log2-ratio):1.886692
Number of Samples:96 / 98
Experimental hypoxia study 7 (high altitude)
Human peripheral monunuclear blood cells taken from the blood of healthy volunteers after acute elevation to high altitude at the South Pole McMurdo station on the third day.
Control hypoxia study 7 (sea level)
Human peripheral monunuclear blood cells taken from the blood of healthy volunteers at sea level at the South Pole McMurdo station on the third day.

Dengue fever study 5 (late) / Dengue fever study 1 (convalescent)

Relative Expression (log2-ratio):-1.7726879
Number of Samples:5 / 11
Experimental Dengue fever study 5 (late)
Peripheral blood mononuclear cell (PBMC) samples derived from the blood of Venezuelan individuals 5 days after the onset of Dengue fever.
Control Dengue fever study 1 (convalescent)
Peripheral blood mononuclear cell (PBMC) samples derived from the blood of Venezuelan individuals 28 days after the onset of Dengue fever.

granulomatosis with polyangiitis study 3 (orbital adipose tissue) / normal orbital adipose tissue

Relative Expression (log2-ratio):-1.6310759
Number of Samples:9 / 22
Experimental granulomatosis with polyangiitis study 3 (orbital adipose tissue)
Orbital adipose tissue samples obtained from patients who suffered from granulomatosis with polyangiitis (GPA). Biopsies were formalin-fixed and paraffin-embedded.
Control normal orbital adipose tissue
Normal orbital adipose tissue samples. Samples were obtained from subjects with no history of orbital disease at the time of surgery such as fat typically excised and discarded as part of routine blepharoplasty or retrobulbar fat that is snared with the eye during enucleation. Biopsies were formalin-fixed and paraffin-embedded.