TOP TEN perturbations for 39168_at (Homo sapiens)
Organism: Homo sapiens
Gene: 39168_at
Selected probe(set): 203043_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 39168_at (203043_at) across 6674 perturbations tested by GENEVESTIGATOR:
adrenal gland cancer study 4 / normal adrenal cortex tissue
Relative Expression (log2-ratio):-2.6540613Number of Samples:43 / 4
Experimental | adrenal gland cancer study 4 |
Primary tumor tissue samples of the adrenal cortex from patients with adrenocortical carcinoma (ACC). | |
Control | normal adrenal cortex tissue |
Histological normal adrenal gland cortical tissue samples derived after autopsy. |
expO kidney cancer study 1 (neoplasm, malignant; primary) / expO kidney cancer study 1 (granular cell carcinoma; primary)
Relative Expression (log2-ratio):2.554922Number of Samples:2 / 4
Experimental | expO kidney cancer study 1 (neoplasm, malignant; primary) |
Primary tumor tissue samples obtained from the kidney of patients with malignant neoplasm. | |
Control | expO kidney cancer study 1 (granular cell carcinoma; primary) |
Primary tumor tissue samples obtained from the kidney of patients with granular cell carcinoma. |
male infertility study 1 (juvenile; Ad-) / normal testicular lobules tissue (mJS10)
Relative Expression (log2-ratio):2.524538Number of Samples:2 / 8
Experimental | male infertility study 1 (juvenile; Ad-) |
Human testicular lobules biopsy samples isolated from prepubescent patients with undescended testes. Testes of these children contained very low level of A-dark (Ad-) spermatogonial cells. | |
Control | normal testicular lobules tissue (mJS10) |
Biopsies of human testicular lobules isolated from fertile vasectomized adult men with normal spermatogenesis. Histological analysis classified samples as mJS10 (modified Johnsen score 10). |
male infertility study 1 (juvenile; Ad+) / normal testicular lobules tissue (mJS10)
Relative Expression (log2-ratio):2.519824Number of Samples:5 / 8
Experimental | male infertility study 1 (juvenile; Ad+) |
Human testicular lobules biopsy samples isolated from prepubescent patients with undescended testes. Testes of these children contained typical level of A-dark (Ad+) spermatogonial cells. | |
Control | normal testicular lobules tissue (mJS10) |
Biopsies of human testicular lobules isolated from fertile vasectomized adult men with normal spermatogenesis. Histological analysis classified samples as mJS10 (modified Johnsen score 10). |
adrenal gland cancer study 2 / normal adrenal cortex tissue
Relative Expression (log2-ratio):-2.2558336Number of Samples:31 / 10
Experimental | adrenal gland cancer study 2 |
Primary tumor tissue samples of the adrenal cortex from patients with adrenocortical carcinoma. | |
Control | normal adrenal cortex tissue |
Unaffected adrenal cortex tissue from control objects. |
adrenal gland cancer study 3 / normal adrenal cortex tissue
Relative Expression (log2-ratio):-2.1967316Number of Samples:2 / 10
Experimental | adrenal gland cancer study 3 |
Relapse tumor sample of the adrenal cortex from patients with recurrent adrenocortical carcinoma. | |
Control | normal adrenal cortex tissue |
Unaffected adrenal cortex tissue from control objects. |
echinomycin study 1 / deferoxamine study 5
Relative Expression (log2-ratio):-2.17723Number of Samples:3 / 3
Experimental | echinomycin study 1 |
Echinomycin (100nM; 2h) treated human astroglioma (U251) cells, stimulated with deferoxamine (DFO; 300mM; 16h). ATC code:--- | |
Control | deferoxamine study 5 |
Untreated human astroglioma (U251) cells, stimulated with deferoxamine (DFO; 300mM; 16h). ATC code: |
propiconazole study 1 (high) / DMSO treated hepatocyte sample
Relative Expression (log2-ratio):-2.0840292Number of Samples:4 / 4
Experimental | propiconazole study 1 (high) |
Primary hepatocytes were exposed to medium containing 100uM propiconazole (high dose) for 72h. ATC code:--- | |
Control | DMSO treated hepatocyte sample |
Primary hepatocytes cultured for 72h in medium containing DMSO 0.1%. |
omeprazole study 6 (600uM) / vehicle (DMSO) treated hepatocyte sample
Relative Expression (log2-ratio):-2.0150661Number of Samples:2 / 2
Experimental | omeprazole study 6 (600uM) |
Hepatocytes treated with compound: omeprazole (600uM; CHEMBL1503) for 24 hours. ATC code: | |
Control | vehicle (DMSO) treated hepatocyte sample |
Hepatocytes treated with vehicle (DMSO) for 24 hours. |
F. tularensis study 1 (novicida) / uninfected peripheral blood monocyte sample
Relative Expression (log2-ratio):-2.0061035Number of Samples:4 / 6
Experimental | F. tularensis study 1 (novicida) |
Peripheral blood monocytes infected with the Francisella tularensis subspecies novicida isolate U112 (100 MOI) for 24 hours. | |
Control | uninfected peripheral blood monocyte sample |
Peripheral blood monocytes uninfected. |