TOP TEN perturbations for 39168_at (Homo sapiens)

Organism: Homo sapiens
Gene: 39168_at
Selected probe(set): 203043_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 39168_at (203043_at) across 6674 perturbations tested by GENEVESTIGATOR:

adrenal gland cancer study 4 / normal adrenal cortex tissue

Relative Expression (log2-ratio):-2.6540613
Number of Samples:43 / 4
Experimental adrenal gland cancer study 4
Primary tumor tissue samples of the adrenal cortex from patients with adrenocortical carcinoma (ACC).
Control normal adrenal cortex tissue
Histological normal adrenal gland cortical tissue samples derived after autopsy.

expO kidney cancer study 1 (neoplasm, malignant; primary) / expO kidney cancer study 1 (granular cell carcinoma; primary)

Relative Expression (log2-ratio):2.554922
Number of Samples:2 / 4
Experimental expO kidney cancer study 1 (neoplasm, malignant; primary)
Primary tumor tissue samples obtained from the kidney of patients with malignant neoplasm.
Control expO kidney cancer study 1 (granular cell carcinoma; primary)
Primary tumor tissue samples obtained from the kidney of patients with granular cell carcinoma.

male infertility study 1 (juvenile; Ad-) / normal testicular lobules tissue (mJS10)

Relative Expression (log2-ratio):2.524538
Number of Samples:2 / 8
Experimental male infertility study 1 (juvenile; Ad-)
Human testicular lobules biopsy samples isolated from prepubescent patients with undescended testes. Testes of these children contained very low level of A-dark (Ad-) spermatogonial cells.
Control normal testicular lobules tissue (mJS10)
Biopsies of human testicular lobules isolated from fertile vasectomized adult men with normal spermatogenesis. Histological analysis classified samples as mJS10 (modified Johnsen score 10).

male infertility study 1 (juvenile; Ad+) / normal testicular lobules tissue (mJS10)

Relative Expression (log2-ratio):2.519824
Number of Samples:5 / 8
Experimental male infertility study 1 (juvenile; Ad+)
Human testicular lobules biopsy samples isolated from prepubescent patients with undescended testes. Testes of these children contained typical level of A-dark (Ad+) spermatogonial cells.
Control normal testicular lobules tissue (mJS10)
Biopsies of human testicular lobules isolated from fertile vasectomized adult men with normal spermatogenesis. Histological analysis classified samples as mJS10 (modified Johnsen score 10).

adrenal gland cancer study 2 / normal adrenal cortex tissue

Relative Expression (log2-ratio):-2.2558336
Number of Samples:31 / 10
Experimental adrenal gland cancer study 2
Primary tumor tissue samples of the adrenal cortex from patients with adrenocortical carcinoma.
Control normal adrenal cortex tissue
Unaffected adrenal cortex tissue from control objects.

adrenal gland cancer study 3 / normal adrenal cortex tissue

Relative Expression (log2-ratio):-2.1967316
Number of Samples:2 / 10
Experimental adrenal gland cancer study 3
Relapse tumor sample of the adrenal cortex from patients with recurrent adrenocortical carcinoma.
Control normal adrenal cortex tissue
Unaffected adrenal cortex tissue from control objects.

echinomycin study 1 / deferoxamine study 5

Relative Expression (log2-ratio):-2.17723
Number of Samples:3 / 3
Experimental echinomycin study 1
Echinomycin (100nM; 2h) treated human astroglioma (U251) cells, stimulated with deferoxamine (DFO; 300mM; 16h). ATC code:---
Control deferoxamine study 5
Untreated human astroglioma (U251) cells, stimulated with deferoxamine (DFO; 300mM; 16h). ATC code:

propiconazole study 1 (high) / DMSO treated hepatocyte sample

Relative Expression (log2-ratio):-2.0840292
Number of Samples:4 / 4
Experimental propiconazole study 1 (high)
Primary hepatocytes were exposed to medium containing 100uM propiconazole (high dose) for 72h. ATC code:---
Control DMSO treated hepatocyte sample
Primary hepatocytes cultured for 72h in medium containing DMSO 0.1%.

omeprazole study 6 (600uM) / vehicle (DMSO) treated hepatocyte sample

Relative Expression (log2-ratio):-2.0150661
Number of Samples:2 / 2
Experimental omeprazole study 6 (600uM)
Hepatocytes treated with compound: omeprazole (600uM; CHEMBL1503) for 24 hours. ATC code:
Control vehicle (DMSO) treated hepatocyte sample
Hepatocytes treated with vehicle (DMSO) for 24 hours.

F. tularensis study 1 (novicida) / uninfected peripheral blood monocyte sample

Relative Expression (log2-ratio):-2.0061035
Number of Samples:4 / 6
Experimental F. tularensis study 1 (novicida)
Peripheral blood monocytes infected with the Francisella tularensis subspecies novicida isolate U112 (100 MOI) for 24 hours.
Control uninfected peripheral blood monocyte sample
Peripheral blood monocytes uninfected.