Organism: Homo sapiens
Gene: 39189_at
Selected probe(set): 228436_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 39189_at (228436_at) across 6674 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):-2.8000002
Number of Samples:3 / 3

Experimental	HIF-1a/HIF-2a depletion study 1 (hypoxia; HK2)
	Proximal tubule epithelial cell line HK-2 with shRNA-mediated stable knock-down of HIF-1a and HIF-2a (Hypoxia-inducible factor 1-alpha and Hypoxia-inducible factor 2-alpha) 24 hours after treatment with hypoxia (20% O2). HK-2 cells were cultured in DMEM/F-12 supplemented with 10% fetal calf serum (FCS), 1% ITS, hydrocortisone, and antibiotics. The cells were incubated at 37 °C.
Control	HIF-1a/HIF-2a depletion study 1 (normoxia; AB81)
	Human podocyte cells AB81 with shRNA-mediated stable knock-down of HIF-1a and HIF-2a (Hypoxia-inducible factor 1-alpha and Hypoxia-inducible factor 2-alpha) 24 hours after treatment with normoxia (20% O2). Conditionally immortalized human podocytes AB81 were cultured under permissive conditions (33 °C) in RPMI-1640 supplemented with 10% FBS, antibiotics, and 1% ITS. Differentiation was induced by thermoshift to 37 °C in 6-well plates.

Relative Expression (log2-ratio):2.4657679
Number of Samples:2 / 2

Experimental	HIV-associated neurocognitive disorder study 7 (normal)
	Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with normal brain pathology. The patients received antiretroviral therapy (ART).
Control	HIV-associated neurocognitive disorder study 6 (normal)
	Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with normal brain pathology. The patients did not receive any antiretroviral therapy (ART).

Relative Expression (log2-ratio):2.299039
Number of Samples:2 / 25

Experimental	colorectal cancer study 43 (metastase; brain)
	Metastatic tumor tissue obtained from the brain of patients with primary colorectal adenocarcinoma.
Control	colorectal cancer study 43 (metastase; liver)
	Metastatic tumor tissue obtained from the liver of patients with primary colon adenocarcinoma.

Relative Expression (log2-ratio):-1.6776218
Number of Samples:15 / 12

Experimental	brain tumor study 1 (pilocytic astrocytoma)
	Primary tumor tissue sample from the brain of patients with pilocytic astrocytoma.
Control	normal brain tissue
	Histologically normal and non-neoplastic tissue sample from different brain anatomical sites of patients with primary brain tumors.

Relative Expression (log2-ratio):-1.6341763
Number of Samples:3 / 3

Experimental	glioma study 17 (glioblastoma; A2B5+)
	Oligodendrocyte progenitor cells (OPC) isolated from high grade glioblastoma (grade IV). OPC were isolated using magnetic-activated cell sorting (MACS) with antibodies against A2B5 antigen. Patients were 66 ± 5 years old males.
Control	non-tumor oligodendrocyte progenitor cell sample (cortex)
	Oligodendrocyte progenitor cells (OPC) isolated from cortical tissue, which was obtained from patients with epilepsy, but without any manifested brain cancer. OPC were isolated using magnetic-activated cell sorting (MACS) with antibodies against A2B5 antigen.

Relative Expression (log2-ratio):-1.6120758
Number of Samples:5 / 7

Experimental	E. coli study 2
	Monocyte-derived macrophage samples derived from healthy control subjects cultured for 4 hours with 2.5 × 105 heat-killed E. coli.
Control	unstimulated, normal monocyte-derived macrophage sample
	Monocyte-derived macrophage samples derived from healthy control subjects cultured for 4 hours unstimulated.

Relative Expression (log2-ratio):1.608737
Number of Samples:11 / 64

Experimental	Merkel cell carcinoma study 3 (metastatic)
	Metastatic tumor tissue from different metastatic sites (skin, lymph node, parotid gland) of patients with Merkel cell carcinoma of the skin.
Control	normal skin tissue
	Normal skin samples from healthy donors.

Relative Expression (log2-ratio):1.5156813
Number of Samples:8 / 10

Experimental	glycogen storage disease type II study 1
	Biceps femoris muscle biopsy sample from patients with infantile onset Morbus Pompe (Pompe disease).
Control	normal biceps tissue
	Biceps femoris biopsy muscle samples from control subjects.

Relative Expression (log2-ratio):-1.5040922
Number of Samples:34 / 12

Experimental	brain tumor study 1 (glioblastoma)
	Primary tumor tissue sample from the brain of patients with glioblastoma multiformae.
Control	normal brain tissue
	Histologically normal and non-neoplastic tissue sample from different brain anatomical sites of patients with primary brain tumors.

Relative Expression (log2-ratio):-1.4601173
Number of Samples:22 / 12

Experimental	brain tumor study 1 (medulloblastoma)
	Primary tumor tissue sample from the brain of patients with medulloblastoma.
Control	normal brain tissue
	Histologically normal and non-neoplastic tissue sample from different brain anatomical sites of patients with primary brain tumors.