TOP TEN perturbations for 39190_s_at (Homo sapiens)

Organism: Homo sapiens
Gene: 39190_s_at
Selected probe(set): 226737_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 39190_s_at (226737_at) across 6674 perturbations tested by GENEVESTIGATOR:

breast cancer study 42 (metastase; liver) / breast cancer study 42 (metastase; chest wall)

Relative Expression (log2-ratio):2.0933247
Number of Samples:3 / 2
Experimental breast cancer study 42 (metastase; liver)
Metastatic tumor tissue obtained from the liver of patients with primary breast adenocarcinoma.
Control breast cancer study 42 (metastase; chest wall)
Metastatic tumor tissue obtained from the chest wall of patients with primary breast adenocarcinoma.

breast cancer study 42 (metastase; lymph node) / breast cancer study 42 (metastase; chest wall)

Relative Expression (log2-ratio):1.513627
Number of Samples:7 / 2
Experimental breast cancer study 42 (metastase; lymph node)
Metastatic tumor tissue obtained from the lymph node of patients with primary breast adenocarcinoma.
Control breast cancer study 42 (metastase; chest wall)
Metastatic tumor tissue obtained from the chest wall of patients with primary breast adenocarcinoma.

HCC study 23 (portal vein infiltration) / adjacent liver tissue

Relative Expression (log2-ratio):-1.4462738
Number of Samples:3 / 10
Experimental HCC study 23 (portal vein infiltration)
Tumor liver tissue samples derived from patients with hepatocellular carcinoma (HCC) with portal vein infiltration. Samples were derived by laser capture microdissection (LCM) from patients with HCC from the Chinese National Human Genome Center at Shanghai.
Control adjacent liver tissue
Normal adjacent liver tissue samples derived from patients with hepatocellular carcinoma (HCC). Samples were derived by laser capture microdissection (LCM) from patients with HCC from the Chinese National Human Genome Center at Shanghai.

estradiol study 17 (1nM; ERa) / control virus infected, estradiol treated MDA Mb231 cell sample

Relative Expression (log2-ratio):1.2654095
Number of Samples:6 / 12
Experimental estradiol study 17 (1nM; ERa)
MDA Mb231 cells were infected with a recombinant adenovirus bearing a cDNA for ERalpha in medium without phenol red and containing 10% CD-FBS for 48h. Cells were then treated with 1 nM estradiol-17beta for 6 hours. ATC code:
Control control virus infected, estradiol treated MDA Mb231 cell sample
Empty vector transfected MDA Mb231 cells were treated with 1 nM estradiol-17beta for 6h. Cells were infected with a recombinant adenovirus bearing no cDNA (CMV) in medium without phenol red and treated 24 hours later. ATC code:

hepatoblastoma study 1 (crowded fetal) / hepatoblastoma study 1 (embryonal)

Relative Expression (log2-ratio):1.2297211
Number of Samples:3 / 7
Experimental hepatoblastoma study 1 (crowded fetal)
Liver tumor tissue samples from children with hepatoblastoma (epithelial type (E-HB); crowded fetal subtype). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group.
Control hepatoblastoma study 1 (embryonal)
Liver tumor tissue samples from children with hepatoblastoma (epithelial type (E-HB); embryonal subtype). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group.

retina pigment epithelium study 1 (adult) / retina pigment epithelium study 1 (fetal)

Relative Expression (log2-ratio):1.1880226
Number of Samples:2 / 6
Experimental retina pigment epithelium study 1 (adult)
Postmortem human native retina pigment epithelium samples from adult individuals.
Control retina pigment epithelium study 1 (fetal)
Human native fetal retina pigment epithelium samples obtained at gestation age between week 16-18.

CVID study 1 (anergic B-cell) / rheumatoid arthritis study 18 (anergic B-cell)

Relative Expression (log2-ratio):-1.1671152
Number of Samples:3 / 2
Experimental CVID study 1 (anergic B-cell)
Anergic naive B-cells (CD19+,CD10-, CD21-/lo, CD27-) from patients suffering from Common Variable Immunodeficiency Disease (CVID).
Control rheumatoid arthritis study 18 (anergic B-cell)
Anergic naive B-cells (CD19+,CD10-, CD21-/lo, CD27-) from patients suffering from rheumatoid arthritis (RA) affecting multiple (subj.ID:19) or all (subj.ID:1) joints.

myotonic dystrophy study 4 (skeletal muscle; DM2) / normal skeletal muscle tisuue (fetal)

Relative Expression (log2-ratio):1.1662531
Number of Samples:8 / 3
Experimental myotonic dystrophy study 4 (skeletal muscle; DM2)
Unspecified skeletal muscle biopsies obtained from patients with myotonic dystrophy type 2 (DM2).
Control normal skeletal muscle tisuue (fetal)
Commercially purchased normal fetal skeletal muscle tissue samples.

phenobarbital study 3 (10000uM) / vehicle (medium) treated hepatocyte sample

Relative Expression (log2-ratio):-1.1646118
Number of Samples:2 / 2
Experimental phenobarbital study 3 (10000uM)
Hepatocytes treated with compound: phenobarbital (10000uM; CHEMBL40) for 24 hours. ATC code:
Control vehicle (medium) treated hepatocyte sample
Hepatocytes treated with vehicle (medium) for 24 hours.

myotonic dystrophy study 4 (biceps brachii; DM1) / normal skeletal muscle tisuue (fetal)

Relative Expression (log2-ratio):1.1454697
Number of Samples:3 / 3
Experimental myotonic dystrophy study 4 (biceps brachii; DM1)
Biceps brachii biopsies obtained from patients with myotonic dystrophy type 1 (DM1).
Control normal skeletal muscle tisuue (fetal)
Commercially purchased normal fetal skeletal muscle tissue samples.