Organism: Homo sapiens
Gene: 39249_at
Selected probe(set): 39248_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 39249_at (39248_at) across 6674 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):-10.190409
Number of Samples:2 / 10

Experimental	Langerhans cell histiocytosis study 2 (multisystem)
	Langerhans cell histiocytes (LCH, CD207+) samples isolated from LCH lesions of patients with multifocal, multisystem (disseminated) disease. Both patients received chemotherapy. Sites of LCH lesions: subj.ID:1 (skin, lungs, multiple skull, mastoid, gingiva), subj.ID:13 (mandible, skull, vertebrae, recurrent orbit, liver, spleen, pituitary gland).
Control	normal epidermal Langerhans cell sample
	Normal epidermal Langerhans cells (CD207+) were isolated from skin of children donors (age < 18 years). The Langerhans cells were isolated from presumably healthy tissue.

Relative Expression (log2-ratio):7.5559845
Number of Samples:2 / 2

Experimental	ovarian tumor study 30 (PDX; transitional cell carcinoma, NOS; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary transitional cell carcinoma, NOS of the ovary (subcutaneously implanted).
Control	ovarian tumor study 30 (PDX; clear cell adenocarcinoma, NOS; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary clear cell adenocarcinoma, NOS of the ovary (subcutaneously implanted).

Relative Expression (log2-ratio):-6.8587313
Number of Samples:40 / 2

Experimental	melanoma study 34 (metastatic)
	Metastatic tumor tissue sample obtained from the patients with metastatic malignant melanoma of the skin. Metastatic samples composed of 22 macroscopic lymph node metastases, 16 subcutaneous metastases and 2 solid organ metastases (adrenal and brain).
Control	melanoma study 34 (in situ)
	Tumor tissue from the skin of patients with melanoma in situ.

Relative Expression (log2-ratio):-6.4268103
Number of Samples:40 / 4

Experimental	melanoma study 34 (metastatic)
	Metastatic tumor tissue sample obtained from the patients with metastatic malignant melanoma of the skin. Metastatic samples composed of 22 macroscopic lymph node metastases, 16 subcutaneous metastases and 2 solid organ metastases (adrenal and brain).
Control	normal skin tissue
	Normal skin tissue.

Relative Expression (log2-ratio):-6.295781
Number of Samples:8 / 10

Experimental	Langerhans cell histiocytosis study 2 (unifocal)
	Langerhans cell histiocytes (LCH, CD207+) samples isolated from LCH lesions of patients with unifocal, single system disease (bone lesion).
Control	normal epidermal Langerhans cell sample
	Normal epidermal Langerhans cells (CD207+) were isolated from skin of children donors (age < 18 years). The Langerhans cells were isolated from presumably healthy tissue.

Relative Expression (log2-ratio):6.2406397
Number of Samples:6 / 12

Experimental	IL-4; GM-CSF study 1 (late)
	Monocytes, cultured with vehicle (DMSO/ethanol) and 500 U/ml IL-4 and 800 U/ml GM-CSF for 5 days. Cytokine treatment was repeated at day 3.
Control	untreated monocyte sample
	Freshly isolated human monocytes from healthy donors.

Relative Expression (log2-ratio):5.942173
Number of Samples:2 / 12

Experimental	PMA study 7 (12h)
	HepG2 cells exposed to 500nM phorbol-12-myristat-13-acetate [(PMA ortetradecanoyl phorbol acetate (TPA)] in DMSO solvent for 12 hours. ATC code:---
Control	vehicle (DMSO) treated HepG2 cell sample
	HepG2 cells exposed to DMSO solvent for 12 hours.

Relative Expression (log2-ratio):5.940277
Number of Samples:2 / 3

Experimental	stem cell differentiation study 41 (hES-T3 EB)
	Sample of embryonic bodies (EB) differentiated from human embryonic stem cells T3 with female karyotype.
Control	undifferentiated hES-T3 cell sample
	Undifferentiated human embryonic stem cells T3.

Relative Expression (log2-ratio):5.918132
Number of Samples:3 / 7

Experimental	diazinon study 1 (24h)
	HepG2 cells exposed to 250μM diazinon in DMSO solvent for 24 hours. ATCvet code:
Control	vehicle (DMSO) treated HepG2 cell sample
	HepG2 cells exposed to DMSO solvent for 24 hours.

Relative Expression (log2-ratio):-5.7396507
Number of Samples:4 / 4

Experimental	OPM-1
	Human primary cancer cell line derived from the peripheral blood of a patient with multiple myeloma. Dexamethasone-resistant. Synonyms:OPM1 Cellosaurus code:
Control	MM1.S
	Human primary cancer cell line derived from the peripheral blood of a patient with multiple myeloma. Dexamethasone-sensitive. Parental cell line:: MM.1 Synonyms:MM.1S; MM1-S; MM-1S; MM1S Cellosaurus code: