TOP TEN perturbations for 39268_at (Homo sapiens)
Organism: Homo sapiens
Gene: 39268_at
Selected probe(set): 210263_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 39268_at (210263_at) across 6674 perturbations tested by GENEVESTIGATOR:
medulloblastoma study 2 / non-tumor brain tissue
Relative Expression (log2-ratio):-2.161934Number of Samples:4 / 9
Experimental | medulloblastoma study 2 |
Primary tumor tissue sample from the infratentorial brain of pediatric patients with large-cell anaplastic medulloblastoma. | |
Control | non-tumor brain tissue |
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor. |
brain tumor study 1 (pilocytic astrocytoma) / brain tumor study 1 (ependymoma)
Relative Expression (log2-ratio):2.0590658Number of Samples:15 / 46
Experimental | brain tumor study 1 (pilocytic astrocytoma) |
Primary tumor tissue sample from the brain of patients with pilocytic astrocytoma. | |
Control | brain tumor study 1 (ependymoma) |
Primary tumor tissue sample from the brain of patients with ependymoma. |
brain tumor study 1 (pilocytic astrocytoma) / brain tumor study 1 (medulloblastoma)
Relative Expression (log2-ratio):2.0574207Number of Samples:15 / 22
Experimental | brain tumor study 1 (pilocytic astrocytoma) |
Primary tumor tissue sample from the brain of patients with pilocytic astrocytoma. | |
Control | brain tumor study 1 (medulloblastoma) |
Primary tumor tissue sample from the brain of patients with medulloblastoma. |
atypical teratoid/rhabdoid tumor study 1 / non-tumor brain tissue
Relative Expression (log2-ratio):-1.9261713Number of Samples:20 / 9
Experimental | atypical teratoid/rhabdoid tumor study 1 |
Primary tumor tissue sample from the brain of pediatric patients with atypical teratoid/rhabdoid tumor (AT/RT). | |
Control | non-tumor brain tissue |
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor. |
ovarian tumor study 16 / normal ovarian surface epithelial cell sample
Relative Expression (log2-ratio):1.7738237Number of Samples:3 / 5
Experimental | ovarian tumor study 16 |
Human epithelial tumor cell samples from the ovary of patients with papillary serous carcinoma. Samples were derived by laser capture microdissection (LCM). | |
Control | normal ovarian surface epithelial cell sample |
Human epithelial cell samples from histopathological normal and non-cancerous ovary tissue. |
medulloblastoma study 1 / non-tumor brain tissue
Relative Expression (log2-ratio):-1.7732Number of Samples:17 / 9
Experimental | medulloblastoma study 1 |
Primary tumor tissue sample from the infratentorial brain of pediatric patients with classical medulloblastoma. | |
Control | non-tumor brain tissue |
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor. |
brain tumor study 1 (ependymoma) / normal brain tissue
Relative Expression (log2-ratio):-1.698926Number of Samples:46 / 12
Experimental | brain tumor study 1 (ependymoma) |
Primary tumor tissue sample from the brain of patients with ependymoma. | |
Control | normal brain tissue |
Histologically normal and non-neoplastic tissue sample from different brain anatomical sites of patients with primary brain tumors. |
brain tumor study 1 (medulloblastoma) / normal brain tissue
Relative Expression (log2-ratio):-1.6972809Number of Samples:22 / 12
Experimental | brain tumor study 1 (medulloblastoma) |
Primary tumor tissue sample from the brain of patients with medulloblastoma. | |
Control | normal brain tissue |
Histologically normal and non-neoplastic tissue sample from different brain anatomical sites of patients with primary brain tumors. |
PMA study 6 (500ng/ml) / vehicle (DME) treated bronchial epithelial cell sample
Relative Expression (log2-ratio):1.4523249Number of Samples:3 / 17
Experimental | PMA study 6 (500ng/ml) |
Bronchial epithelial cells (NHBE) treated with tetradecanoylphorbol acetate (500ng/ml; vendor: Sigma / catalog number: P1585 / catalog name: Phorbol 12-myristate 13-acetate [16561-29-8]) for 6 hours. For treatment primary cells were seeded at a density of 50'000 cells/well in pre-coated rat tail collagen type I 96-well plates for 24 hours followed by 4 hours starvation. NHBE cells were isolated from different Caucasian, healthy and non-smoker donors from the airway located above the bifurcation of the lungs (tracheal/bronchial). ATC code:--- | |
Control | vehicle (DME) treated bronchial epithelial cell sample |
Bronchial epithelial cells (NHBE) treated with vehicle (DME) for 6 hours. For treatment primary cells were seeded at a density of 50'000 cells/well in pre-coated rat tail collagen type I 96-well plates for 24 hours followed by 4 hours starvation. NHBE cells were isolated from different Caucasian, healthy and non-smoker donors from the airway located above the bifurcation of the lungs (tracheal/bronchial). |
glioma study 17 (astrocytoma; A2B5+) / non-tumor oligodendrocyte progenitor cell sample (cortex)
Relative Expression (log2-ratio):-1.4488335Number of Samples:3 / 3
Experimental | glioma study 17 (astrocytoma; A2B5+) |
Oligodendrocyte progenitor cells (OPC) isolated from low grade astrocytoma (grade II). OPC were isolated using magnetic-activated cell sorting (MACS) with antibodies against A2B5 antigen. Patients were 36 ± 7 years old. | |
Control | non-tumor oligodendrocyte progenitor cell sample (cortex) |
Oligodendrocyte progenitor cells (OPC) isolated from cortical tissue, which was obtained from patients with epilepsy, but without any manifested brain cancer. OPC were isolated using magnetic-activated cell sorting (MACS) with antibodies against A2B5 antigen. |